Despite recent advances, the pathogenesis and therapy of various forms of chronic inflammatory diseases of the gastrointestinal tract remains problematical. Especially threatening is the possible complication of the development of a malignant growth, but the role of the chronic inflammatory process in this is not known. Three examples are: H. pylori-induced gastritis is associated with gastric lymphomas and carcinomas; there is an increased incidence of intestinal T-cell lymphomas in tropical sprue; and chronic inflammatory bowel diseases, particularly ulcerative colitis, are associated with an increased incidence of carcinoma. In this book, the Proceedings of Falk Symposium No. 81, held in Berlin, November 3-5, 1994, an extensive exchange of information and opinions between international experts yields a state-of-the-art consensus on practical procedures in diagnostics, prophylaxis and therapy.

Inhalt: -Klinik, Genetik und Immunologie der leukozyt{ren Adh{sions- proteindefizienzen T. Uhlig und B.H. Behloradsky -Herkunft numerischer und struktureller Aberrationen des X-Chromosoms I. Lorda-Sanchez und A.A. Schinzel -Die chronische hepatische Porphyrie (Porphyria cutanea tarda) E. K-stler und M.O. Doss -Die Legionelleninfektion G. Ruckdeschel und W. Ehret -Das Wiedemann-Beckwith-Syndrom J. Kunze

Inhalt: -Hereditare Pankreatitis H. Tomsik, R. Grun und E. Wagner -Der Gastrointestinaltrakt als Metastasensitz maligner epithelialer Tumoren S. Madeya und G. Borsch -Infektionen durch Streptokokken der Gruppe B bei Neuge- borenen und Kindern R. Roos, S. Buhler, H. Kraeft und W. Handrick -Das Ch diak-Higashi-Syndrom B.H. Belohradsky und B. Laminger -Impfungen bei sekundaren Immundefekten - Indikationen, Impferfolge und Komplikationen B.H. Belohradsky und L. Nissl