This touching autobiography charts the incredible life of a Yorkshire-born lad whose life story could match any Hollywood script.Using his childhood talent of motorcycle racing he becomes a stunt rider performing at many local shows. When World War II breaks out his skill transfers perfectly to the role of despatch rider for the Royal Corps of Signals. This eventful journey takes him all over the world, till he is captured whilst serving in North Africa and transferred to a prisoner of war camp in Italy. Luckily, his farming expertise means he is sent to work on local farmland, which enables his daring escape, aided by the partisans.Despite living such a spectacular life, Nicholson remains a stoical, down-to-earth man and tells his story with an openness and enthusiasm which is heart-warming, and will remind you of the indomitable spirit which makes Britain great.

The receptor-associated JAK protein kinases and their substrates, the STAT transcriptional activators, transmit signals following cytokine and growth factor binding to receptors expressed on the cell surface, to result in specific transcriptional and cellular responses. Over the last two decades, the field has progressed from identification of the individual components through to an understanding of the activation and deactivation mechanisms, and the complex structural detail of the proteins involved. We now know that these pathways are important in many biological processes, including growth and development, hematopoiesis, and the innate and adaptive immune response. JAK-STAT Signalling: Methods and Protocols provides detailed methodologies for examining many aspects of the pathway. Divided into four sections, topics include JAK and STAT specific approaches, the negative regulators of the pathway (SOCS proteins), and the production and crystallization of JAK and STAT proteins, among others. Written in the successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, JAK-STAT Signalling: Methods and Protocols will be of use not only to those working in the area but also to new investigators who are led to delve into the complexities of JAK and STAT responses.

The receptor-associated JAK protein kinases and their substrates, the STAT transcriptional activators, transmit signals following cytokine and growth factor binding to receptors expressed on the cell surface, to result in specific transcriptional and cellular responses. Over the last two decades, the field has progressed from identification of the individual components through to an understanding of the activation and deactivation mechanisms, and the complex structural detail of the proteins involved. We now know that these pathways are important in many biological processes, including growth and development, hematopoiesis, and the innate and adaptive immune response. JAK-STAT Signalling: Methods and Protocols provides detailed methodologies for examining many aspects of the pathway. Divided into four sections, topics include JAK and STAT specific approaches, the negative regulators of the pathway (SOCS proteins), and the production and crystallization of JAK and STAT proteins, among others. Written in the successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, JAK-STAT Signalling: Methods and Protocols will be of use not only to those working in the area but also to new investigators who are led to delve into the complexities of JAK and STAT responses.

A comprehensive review of dryland climates and their relationship to the physical environment, hydrology, and inhabitants. Chapters are divided into five major sections on background meteorology and climatology; the nature of dryland climates in relation to precipitation and hydrology; the climatology and climate dynamics of the major dryland regions on each continent; and life and change in the world's drylands. It includes key topics such as vegetation, geomorphology, desertification, micro-habitats, and adaptation to dryland environments. This interdisciplinary volume provides an extensive review of the primary literature (covering nearly 2000 references) and the conventional and satellite datasets that form key research tools for dryland climatology. Illustrated with over 300 author photographs, it presents a unique view of dryland climates for a broad spectrum of researchers, environmental professionals and advanced students in climatology, meteorology, geography, environment science, earth system science, ecology, hydrology and geomorphology.

Foreword By G. Warfield Hobbs III And Edwin B. Morris, Jr.

Berthold Auerbach (1812-1882) was a German-Jewish poet and author, considered the founder of the German "tendency novel," which uses fiction as a means of influencing the public about social, political, moral, and religious issues. His novel about the Dutch philosopher Baruch de Spinoza (1632-1677), chronicles his development from rabbinical student to one of the great rationalists of 17th-century philosophy.

Foreword By G. Warfield Hobbs III And Edwin B. Morris, Jr.

Was the Beowulf-poet a Christian or was he a noble pagan whose outlook had been only slightly colored by exposure to Christian thinking? This is but one of the fascinating topics discussed in this anthology of criticism on the early medieval masterpiece. The eighteen contribution to the anthology are arranged chronologically according to the date of the criticism's first publication. The outstanding scholars whose critical writing is presented here range from the turn-of-the-century critic F. A. Blackburn through the Englishman J. R. R. Tolkien to such contemporaries as Kemp Malone, Morton Bloomfield, and R. E. Kaske. Nearly every aspect of the Beowulf is discussed and controverted in terms of literary analysis. Old English, Old Norse, Latin, and Old French passages are translated in the accompanying text as an aid to undergraduate students meeting Beowulf for the first time.

Was the Beowulf-poet a Christian or was he a noble pagan whose outlook had been only slightly colored by exposure to Christian thinking? This is but one of the fascinating topics discussed in this anthology of criticism on the early medieval masterpiece. The eighteen contribution to the anthology are arranged chronologically according to the date of the criticism's first publication. The outstanding scholars whose critical writing is presented here range from the turn-of-the-century critic F. A. Blackburn through the Englishman J. R. R. Tolkien to such contemporaries as Kemp Malone, Morton Bloomfield, and R. E. Kaske. Nearly every aspect of the Beowulf is discussed and controverted in terms of literary analysis. Old English, Old Norse, Latin, and Old French passages are translated in the accompanying text as an aid to undergraduate students meeting Beowulf for the first time.

A comprehensive review of dryland climates and their relationship to the physical environment, hydrology, and inhabitants. Chapters are divided into five major sections on background meteorology and climatology; the nature of dryland climates in relation to precipitation and hydrology; the climatology and climate dynamics of the major dryland regions on each continent; and life and change in the world's drylands. It includes key topics such as vegetation, geomorphology, desertification, micro-habitats, and adaptation to dryland environments. This interdisciplinary volume provides an extensive review of the primary literature (covering nearly 2000 references) and the conventional and satellite datasets that form key research tools for dryland climatology. Illustrated with over 300 author photographs, it presents a unique view of dryland climates for a broad spectrum of researchers, environmental professionals and advanced students in climatology, meteorology, geography, environment science, earth system science, ecology, hydrology and geomorphology.