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Omnibus 37 (Afrikaans, Paperback): Ena Murray Omnibus 37 (Afrikaans, Paperback)
Ena Murray
R703 Discovery Miles 7 030 Ships in 10 - 15 working days

Met die oorspronklike publikasie van die drie romans oor die wel en wee van vier geslagte Meissners het Ena Murray opnuut haar status as koningin van die Afrikaanse liefdesverhaal gestand gedoen. Die drieluik bestaan uit: Die Meissner-kliniek, waar ons die die stigter van die eksklusiewe privaat kliniek en sy gedugte span dokters ontmoet. Die vrede word in 'n oogwink omvergewerp wanneer 'n nuwe trolliejoggie daar begin werk ... Dokter Julene, waar Julene die veilige hawe van die Meissner-kliniek verlaat om by haar biologiese pa in Switserland aan te sluit ... en dan onverwags in Istanboel beland. En Die ongebore uur, waar Inge Buchner, die agterkleindogter van dr. Albert Meissner, alles in haar vermoe doen om te probeer verseker dat iemand met die van Meissner weer aan die hoof van die kliniek sal staan.

Die rooi rok (Afrikaans, Hardcover, 2nd ed): Dux van der Walt, Ena van der Walt Die rooi rok (Afrikaans, Hardcover, 2nd ed)
Dux van der Walt, Ena van der Walt; Illustrated by Anneliese Voigt-Peters
R153 Discovery Miles 1 530 Ships in 4 - 8 working days

Ouma het vir Doortjie n pragtige rooi rok vir Krismis gemaak. Sy is so opgewonde dat sy besluit om die rok sommer al n dag vroeer aan te trek om water by die windpomp te gaan haal en haar skilpad te voer. Maar toe die rok erg verniel, moet Doortjie dringend planne beraam sodat Ouma nie agterkom sy het dit skelm gedra nie.

Die Tienduisend Dinge (Afrikaans, Paperback): Maria Dermout Die Tienduisend Dinge (Afrikaans, Paperback)
Maria Dermout; Translated by Ena Jansen
R282 Discovery Miles 2 820 Ships in 4 - 8 working days

De tienduizend dingen (1955) is Maria Dermot se beroemdste boek en is in vyftien tale vertaal. Dit is die sintuiglike en kaleidoskopiese verhaal van Felicia, “mevrou van Kleyntjies”, wat woon op 'n onskynlik paradyslike Molukse eiland, in 'n huis aan die binnebaai.

Die titel is ontleen aan 'n uitspraak van Ts'n Shn: “Wanneer die 'tienduisend dinge' in hulle eenheid gesien is, keer ons terug na die begin en bly waar ons altyd was.” Hieruit blyk Dermot se Boeddhistiese ingesteldheid: 'n sprankelende viering van die natuur en die lewe, en tegelyk 'n gelatenheid oor die verbygaan van tyd.

Die opvallendste tema in Dermot se werk is verlies: verdriet oor die dood en die afwesigheid van geliefdes, oor geweld en wreedheid, en oor eensaamheid. Verdriet word getemper deur 'n omvattende liefde vir 'dinge': plante, skulpe, korale, golfies wat breek. n deur berusting en aanvaarding van jou lot.

Ons Japie - Die Boereoorlogdagboek van Anna Barry (Afrikaans, Paperback): Anna Barry Ons Japie - Die Boereoorlogdagboek van Anna Barry (Afrikaans, Paperback)
Anna Barry; Compiled by Ena Jansen
R239 Discovery Miles 2 390 Ships in 4 - 8 working days

Wanneer n mens aan die ervarings van Boerevroue en -kinders tydens die Anglo-Boereoorlog dink, is die outomatiese konnotasie die van konsentrasiekamplyding. n Fassinerende en grotendeels onbekende buitebeentjie in hierdie genre is die dagboek van Anna Barry, waaruit n unieke en veelkantige beeld van die oorlog na vore kom. Aan die een kant van Anna se oorlogservaring staan haar broer Japie n begeesterde jong soldaat wat uiteindelik as krygsgevangene op Ceylon sterf. Hierteenoor le haar geliefde pa Thomas (aanvanklik n gerespekteerde veldkornet) al in 1900 die eed van neutraliteit af, en wag hy die grootste gedeelte van die oorlog in die neutrale Basoetoland uit. Vir die tienderjarige Anna is die oorlog as gevolg hiervan n uiters verwarrende ervaring en haar dagboek bied n sonderlinge blik op die gefragmenteerdheid en buigbaarheid van konsepte soos identiteit, nasie en volk. Die feit dat die dagboek eers in 1960 vir die eerste keer gepubliseer is en daarna grotendeels in die vergetelheid verval het, is verder veelseggend in terme van hoe Anna self verwag het haar ervarings kort na die oorlog ontvang sou word maar ook in terme van hoe blinde lojaliteit aan sekere groepe so dikwels in die geskiedenis van Suid-Afrikaners vereis is. Die dagboekteks, geboekstut deur Ena Jansen se insiggewende en verhelderende voor- en nawoord, bied nie slegs n sonderlinge blik op die Anglo-Boereoorlog nie, maar is verweef met kwessies van taal, politieke mag en sosiale status wat vandag nog net so relevant is soos toe die dagboek geskryf is.

Immigrant - 'n Keuse Uit Die Gedigte Van Elisabeth Eybers (Afrikaans, Paperback): Ena Jansen, Elisabeth Eybers Immigrant - 'n Keuse Uit Die Gedigte Van Elisabeth Eybers (Afrikaans, Paperback)
Ena Jansen, Elisabeth Eybers
R335 R288 Discovery Miles 2 880 Save R47 (14%) Ships in 4 - 8 working days

Eybers se verse was jare laas in druk. Di keuse, uitgesoek deur Ena Jansen, goeie vriendin van haar, wys op Eybers se veelsydigheid as digter. Die bloemlesing behels o.m. die bekende "Maria", "Busrit in die aand", verse oor haar kinders, die emigrasie na Nederland, tot haar latere, aangrypende gedigte oor ouer word. Goeie posie is tydloos, en dit blyk duidelik met di uitgawe van Eybers se bekendste werk.

Sheehy's Emergency Nursing - Principles and Practice (Hardcover, 6th Revised edition): Emergency Nurses Association, Ena Sheehy's Emergency Nursing - Principles and Practice (Hardcover, 6th Revised edition)
Emergency Nurses Association, Ena
R3,868 Discovery Miles 38 680 Ships in 10 - 15 working days

Written by emergency nurses for emergency nurses, this comprehensive, evidence-based resource covers the issues and procedures that are often unique to the emergency department. New developments and changes in clinical practice are incorporated throughout. The user-friendly format features more than 350 high-quality illustrations and 150 tables that highlight essential concepts and offer quick access to vital information. Key coverage includes clinical fundamentals, treatment for trauma and medical-surgical emergencies, the foundations of emergency nursing practice, and special populations. 58 contributors offer valuable insights from a broad range of clinical positions in rural, suburban, and urban areas. High-quality radiographs and other diagnostic images help you learn to identify common conditions - especially head trauma, fractures, and dislocations. Logically organized, chapters are grouped into six sections for quick access to important content: Foundations of Emergency Nursing, Professional Practice, Clinical Foundations of Emergency Nursing, Major Trauma Emergencies, Medical and Surgical Emergencies, and Special Patient Populations. Tables and boxes highlight and summarize critical information for at-a-glance reference. A separate unit on special patient populations covers topics such as child abuse, elder abuse, intimate partner violence, sexual assault, substance abuse and behavioral/pediatric/obstetrical emergencies. Priority nursing diagnoses are highlighted in a quick-reference appendix to help you focus on the most serious problems. Five new chapters bring you the most reliable, up-to-date information on these key topics: Management of the Critical Care Patient in the Emergency Department Family Presence During Resuscitation Forensic Nursing Nuclear, Biological, and Chemical Agents of Mass Destruction Influenza: Seasonal, Avian, and Pandemic Expanded coverage of shock and sepsis provides essential information on pathophysiology and diagnosis, with valuable guidelines for managing these patients. A detailed discussion of various types of triage systems and triage acuity ratings examines valid and reliable methods for differentiating between patients who require immediate treatment and those who can wait. Additional coverage of behavioral health emergencies includes new information on agitation, substance abuse, and suicide prevention.

Men Should Weep by Ena Lamont Stewart: School Edition (Paperback): Ena Lamont Stewart, Donna Gray Men Should Weep by Ena Lamont Stewart: School Edition (Paperback)
Ena Lamont Stewart, Donna Gray
R418 Discovery Miles 4 180 Ships in 9 - 15 working days

A Schools Edition of Men Should Weep by Scottish playwright Ena Lamont Stewart, a popular set text for SQA Higher English. Set in the 1930s, Men Should Weep centres on the challenges faced by the Morrison family. This riveting portrayal of life in Glasgow's slums explores themes such as poverty, love and the role of women. This edition includes: - An educational introduction with an overview of the play and playwright - The full playscript - Notes on the text, key quotations and questions to improve students' understanding of the play - Tasks and activities designed to support study/revision and build the skills of analysis and evaluation - Assessment advice for the Critical Reading question paper

The Red Dress (Hardcover, 2nd ed): Dux van der Walt, Ena van der Walt The Red Dress (Hardcover, 2nd ed)
Dux van der Walt, Ena van der Walt; Illustrated by Anneliese Voigt-Peters
R153 Discovery Miles 1 530 Ships in 4 - 8 working days
Sheehy's Manual of Emergency Care (Paperback, 8th edition): Ena Sheehy's Manual of Emergency Care (Paperback, 8th edition)
Ena
R1,818 Discovery Miles 18 180 Ships in 12 - 17 working days

Sheehy's Manual of Emergency Care, 8th Edition offers complete, up-to-date coverage of the essentials emergency nurses need to know. Each condition commonly seen in the emergency setting is thoroughly addressed, from signs and symptoms, to diagnosis, treatment, developmental considerations, patient education, and more. Updated material and easy-to-reference contents make this resource a must-have for current practice. Quick-reference format is ideal for updating emergency nursing knowledge and improving patient care. Detailed discussions for each condition include signs and symptoms, diagnosis/diagnostic testing, treatment/interventions, age/developmental considerations, and patient/family education/discharge instructions. Authorship from the Emergency Nurses Association for more than 30 years ensures this book is a mainstay for best practices in emergency nursing. Content presented in a bulleted format provides quick and easy access to vital information. Practice points highlighted in special boxes offer quick reference to important content. NEW! Restructured table of contents presents anatomically related medical and trauma chapters sequentially for quick reference. NEW! Considerations for critical care in the ED. NEW! Considerations for the transgender patient. NEW! Section on human trafficking in the Interpersonal Violence and Abuse chapter. NEW! Section on violent risk assessment in the Workplace Violence chapter. NEW! Color photos insert visually highlights and clarifies key content. EXPANDED! Substance Abuse and Addiction Emergencies chapter covers methamphetamines, bath salts, marijuana edibles, opioid abuse/prescription drug abuse, heroin/Narcan, and substance abuse disorder. EXPANDED! Chapter on end-of-life includes information on palliative care considerations. UPDATED! Infectious Diseases chapter addresses coronavirus 19 (COVID-19), Ebola, and vector-borne malaria.

A Close Shave With The Devil - Stories of Dublin (Paperback): Ena May A Close Shave With The Devil - Stories of Dublin (Paperback)
Ena May
R219 Discovery Miles 2 190 Ships in 12 - 17 working days

'The devil was going around again and everyone knew because it was in the papers. An usherette in the Metropole saw him at An Apartment for Peggie, eating oranges in a brown trilby; two women in Clery's Bargain Basement came upon him fingering cups in a highly suspicious manner; and The Evening Mail said pretty draper's assistant, Lily Shine, nineteen, from Cabra West, was dancing with a fellow in a brown suit when she felt something funny, looked down, and fainted.' In these unsettling tales of late 1940s Dublin, young Eily Doolin encounters the gentle foot-fetishist next door, the 'Argentinian tango-dancer' from Ballybough, the Jewish couple who introduce her to the delights of carrot cake and Chopin, the 'simple' boy who carries a secret hatred, and, in the climactic closing story, the devil himself. Along the way there are two murders, a suicide, and more illicit sex than Eily can comprehend. Ena May's post-Emergency Dublin is at once recognizable and utterly unlike all previous literary versions of the city. Her gimlet-eyed narrator inhabits secret childhood places as well as the grown-up kitchens and parlours of 'Blarney Park', twitching the veil between public and private, street and home. Ena May has created a remarkable narrative voice, perfectly pitched between the knowing and the naive, the compassionate and the sarcastic, the intrepid and the bewildered. A Close Shave with the Devil, fables of adults at play in a child's world, is a tour de force of storytelling, and a remarkable debut collection.

Six Feet Below Zero (Paperback): Ena Jones Six Feet Below Zero (Paperback)
Ena Jones
R290 R247 Discovery Miles 2 470 Save R43 (15%) Ships in 10 - 15 working days
Ena Murray Keur 18 (Afrikaans, Paperback): Ena Murray Ena Murray Keur 18 (Afrikaans, Paperback)
Ena Murray
Sold By Readers Warehouse - Fulfilled by Loot
R260 R219 Discovery Miles 2 190 Save R41 (16%) In Stock

In Eiland in die son​ begin Willemien se stryd om oorlewing – saam met ’n geheimsinnige vreemdeling en ’n jaloerse miljoenrsvrou – toe haar vliegtuig in ’n tropiese oerwoud neerstort. Hoe kn sy haarself so totaal vergeet in die arms van ’n vreemdeling? Dt terwyl sy op trou staan met Ian, wat k in die ongeluk was, maar nou nrens te vinde is nie.

Andrea Smit besluit om haar pa op ’n avontuur te vergesel in Seor die seerower – min wetende dat haar pad op ’n tropiese eiland met di van ’n aantreklike Spanjaard sal kruis; en dat sy sodoende in allerhande onmoontlike situasies sal beland . . .

In Sluiers van wierook ontspoor Ida Herbst se planne om deel te wees van ’n soektog na water in Saoedi-Arabi se grootste woestyn. Sy moet haar vriendin Ansie opspoor, en die enigste oplossing is om haarself gewilliglik in prins Ibrahim Hazik se kloue te begewe. Boonop ontketen die geheimsinnige Georg ongekende emosies in haar hart.

Scilly - Through the Eyes of the 'Duchess' of Auriga - Snapshots of a Bygone Scillonian Era (Hardcover): Jeremy... Scilly - Through the Eyes of the 'Duchess' of Auriga - Snapshots of a Bygone Scillonian Era (Hardcover)
Jeremy Reseigh Watts; Photographs by Ena Reseigh
R560 Discovery Miles 5 600 Ships in 12 - 17 working days

An affectionate, light-hearted and nostalgic look back at the Isles of Scilly of the 20th Century through the photographs of Ena Reseigh.

Boer En Brit: Afrikaanse En Nederlandse Tekste Uit En Om Die Anglo-Boereoorlog (Afrikaans, Dutch, English, Hardcover): Ena... Boer En Brit: Afrikaanse En Nederlandse Tekste Uit En Om Die Anglo-Boereoorlog (Afrikaans, Dutch, English, Hardcover)
Ena Jansen, Wilfred Jonckheere
R115 Discovery Miles 1 150 Ships in 4 - 8 working days
Men Should Weep (Paperback, New edition): Ena Lamont Stewart Men Should Weep (Paperback, New edition)
Ena Lamont Stewart
R407 Discovery Miles 4 070 Ships in 12 - 17 working days

Written for Glasgow Unity in 1947, this extraordinarily moving play of women surviving in the east end of Glasgow of the 1930s was revived by 7:84 Company to tremendous critical acclaim. It finds in the lives of Maggie, her family and her neighbours not only all the tragedy that appalling housing, massive unemployment and grinding poverty can produce, but alo a rich vein of comedy - the sense of the ridiculous, the need for a good laugh.

Perspectives in Regenerative Medicine (Paperback, Softcover reprint of the original 1st ed. 2014): Ena Ray Banerjee Perspectives in Regenerative Medicine (Paperback, Softcover reprint of the original 1st ed. 2014)
Ena Ray Banerjee
R3,572 Discovery Miles 35 720 Ships in 10 - 15 working days

The information given in this book tries to capture the essence of the sheer dynamicity of the cell along with useful tips on how to address critical rate limiting steps in the process of exploration and investigation of its capacity to regenerate, rebuild and replenish from within. The definitions of stem cells, stemness, and the niche concept continue to undergo revisions. In adult vertebrates, hematopoietic and some non-hematopoietic progenitors are synthesized within specialized niches of bone marrow. They migrate to designated tissues, and are either trans-differentiated or become quiescent and settle down. These form the stem cell niche reservoir in all tissues. Not only the primary hematopoietic tissue but all organs and tissues are also capable of generating progenitors which are either synthesized from these migrants or are direct recruits from other tissues. In the niches, the cells settle down and await their turn to either make more clones like themselves or differentiate and mobilize in an exigency. Thus progenitors are important reserves, to be multiplied and deployed or travel as important message bearing molecules via blood as circulating progenitors which can home to their allocated destinations. Upon reaching, specific integrins and selectins help them “dock” and “port” and they may be reprogrammed to induce further differentiation and help repopulate the denuded tissue. In pulmonary fibrosis and asthma, progenitors from both systemic circulation and local stem cell niches have been found to participate in the myriad ramifications of repair, replacement and regeneration of lost or diseased tissue. Whether they are lung specific or global in origin and role remain to be explored. Research tools, fundamental concepts, techniques, methodologies and standard operating protocols and animal models and human extrapolations, have been discussed in a concise way along with detailed description and discussion on the appropriate rationale to introduce the subject to the casual reader and provide valuable tactical information to the specialist in Regenerative Medicine. I sincerely hope you enjoy the work and appreciate the hard work that has gone into designing and executing elegant experiments by many researchers in the field. The branch is multi-disciplinary and I hope that the readers will not be limited to biologists alone.

Geometry from Dynamics, Classical and Quantum (Paperback, Softcover reprint of the original 1st ed. 2015): José F. Cariñena,... Geometry from Dynamics, Classical and Quantum (Paperback, Softcover reprint of the original 1st ed. 2015)
José F. Cariñena, Alberto Ibort, Giuseppe Marmo, Giuseppe Morandi
R4,373 Discovery Miles 43 730 Ships in 10 - 15 working days

This book describes, by using elementary techniques, how some geometrical structures widely used today in many areas of physics, like symplectic, Poisson, Lagrangian, Hermitian, etc., emerge from dynamics. It is assumed that what can be accessed in actual experiences when studying a given system is just its dynamical behavior that is described by using a family of variables ("observables" of the system). The book departs from the principle that ''dynamics is first'' and then tries to answer in what sense the sole dynamics determines the geometrical structures that have proved so useful to describe the dynamics in so many important instances. In this vein it is shown that most of the geometrical structures that are used in the standard presentations of classical dynamics (Jacobi, Poisson, symplectic, Hamiltonian, Lagrangian) are determined, though in general not uniquely, by the dynamics alone. The same program is accomplished for the geometrical structures relevant to describe quantum dynamics. Finally, it is shown that further properties that allow the explicit description of the dynamics of certain dynamical systems, like integrability and super integrability, are deeply related to the previous development and will be covered in the last part of the book. The mathematical framework used to present the previous program is kept to an elementary level throughout the text, indicating where more advanced notions will be needed to proceed further. A family of relevant examples is discussed at length and the necessary ideas from geometry are elaborated along the text. However no effort is made to present an ''all-inclusive'' introduction to differential geometry as many other books already exist on the market doing exactly that. However, the development of the previous program, considered as the posing and solution of a generalized inverse problem for geometry, leads to new ways of thinking and relating some of the most conspicuous geometrical structures appearing in Mathematical and Theoretical Physics.

Perspectives in Inflammation Biology (Paperback, Softcover reprint of the original 1st ed. 2014): Ena Ray Banerjee Perspectives in Inflammation Biology (Paperback, Softcover reprint of the original 1st ed. 2014)
Ena Ray Banerjee
R5,069 Discovery Miles 50 690 Ships in 10 - 15 working days

“Perspectives in Inflammation Biology” outlines detailed studies using preclinical murine models in Inflammation. The book is meant for academicians, industry persons, research scholars and students alike. The detailed perspective for a beginner and the exhaustive methodologies and analyses outlined, for the veteran researcher, makes this book a unique link between someone who is thinking of embarking on a study of inflammation and one who is delving deep into this area of specialization. The book deals with asthma and allergy as specific disease areas of inflammation of the lung, aseptic peritonitis as a disease of systemic inflammation and details how each role player in its pathophysiology has a unique niche of activity. Data acquisition, sequentiality and analyses in context demonstrate how each role player is validated systematically to become a target for drug discovery. Methods and models used in the course of my work and their relevance will demonstrate to the researcher how a study can be developed from an idea. Further into a researcher’s ongoing work, this book is meant to stimulate new questions and pave ways for better dissection of a phenomenon. The highlights of this book are the detailed tables tabulating sub species of immune cells, their inflammatory recruitment indices, their translation into tissue-to-tissue traffic of the inflammatory stimulus and the delicate interplay of resident structural cells, cells recruited from circulation, their feedback poiesis in bone marrow, their instruction in the lymphoid organs and tissues as well as the non-cellular mediators synthesized from corresponding genetic instruction. The book shall definitely help students and researchers how a disease can be simplified from its complex ramifications and network of implications and put back into perspective and the whole thing falls into place without an intimate understanding of the mechanism and the compelling circumstances that causes a disease, a drug hunter cannot hope to begin her quest. To find the “Achilles’ heel” and effectively neutralize the enemy!

Treating Child Sexual Abuse in Family, Group and Clinical Settings - Culturally Intelligent Practice for Caribbean and... Treating Child Sexual Abuse in Family, Group and Clinical Settings - Culturally Intelligent Practice for Caribbean and International Contexts (Hardcover, 1st ed. 2016)
Adele D. Jones, Ena Trotman Jemmott, Hazel Da Breo, Priya Maharaj
R1,586 Discovery Miles 15 860 Ships in 10 - 15 working days

Presenting real-life case studies of child sexual abuse in the Caribbean as a basis for discussing interventions and models of practice that are relevant for a wide range of cultural and social settings, this multi-disciplinary text will be of interest to scholars, professionals and practitioners alike. Contributors to this volume demonstrate how sexual abuse is never just a problem of the individual: structures of inequality and the intersection of the factors they give rise to help to explain why some children are more at risk of abuse than others. Furthermore, the sub-systems in which lives are lived can compound risk and vulnerability or alternatively, can be sources of support and change. This book draws on these ideas to discuss practice across a range of service users: children, adolescent girls, teenage mothers, children with learning disabilities, fathers, mothers, women who abuse, juvenile sex offenders and children in residential care. p>

A Companion to Julian of Norwich (Paperback): Liz Herbert McAvoy A Companion to Julian of Norwich (Paperback)
Liz Herbert McAvoy; Contributions by Annie Sutherland, Barry A. Windeatt, Cate Gunn, Denise N. Baker, …
R788 Discovery Miles 7 880 Ships in 12 - 17 working days

One of the most important medieval writers studied in historical and literary context. Julian of Norwich, the fourteenth/early fifteenth-century anchoress and mystic, is one of the most important and best-known figures of the Middle Ages. Her Revelations, intense visions of the divine, have been widely studied and read; the first known writings of an English woman, their influence extends over theology and literature. However, many aspects of both her life and thought remain enigmatic. This exciting new collection offers a comprehensive, accessible coverage of the key aspects of debate surrounding Julian. It places the author within a wide range of contemporary literary, social, historical and religious contexts, and also provides a wealth of new insightsinto manuscript traditions, perspectives on her writing and ways of interpreting it, building on the work of many of the most active and influential researchers within Julian studies, and including the fruits of the most recent,ground-breaking findings. It will therefore be a vital companion for all of Julian's readers in the twenty-first century. Dr Liz Herbert McAvoy is Senior Lecturer in Gender in English and Medieval Studies at Swansea University. Contributors: Denise M. Baker, Alexandra Barratt, Marleen Cre, Elisabeth Dutton,Vincent Gillespie, Cate Gunn, Ena Jenkins, E.A. Jones, Liz Herbert McAvoy, Laura Saetveit Miles, Kim M. Philips, Elizabeth Robertson,Sarah Salih, Annie Sutherland, Diane Watt, Barry Windeatt.

Perspectives in Regenerative Medicine (Hardcover, 2014 ed.): Ena Ray Banerjee Perspectives in Regenerative Medicine (Hardcover, 2014 ed.)
Ena Ray Banerjee
R3,952 Discovery Miles 39 520 Ships in 10 - 15 working days

The information given in this book tries to capture the essence of the sheer dynamicity of the cell along with useful tips on how to address critical rate limiting steps in the process of exploration and investigation of its capacity to regenerate, rebuild and replenish from within. The definitions of stem cells, stemness, and the niche concept continue to undergo revisions. In adult vertebrates, hematopoietic and some non-hematopoietic progenitors are synthesized within specialized niches of bone marrow. They migrate to designated tissues, and are either trans-differentiated or become quiescent and settle down. These form the stem cell niche reservoir in all tissues. Not only the primary hematopoietic tissue but all organs and tissues are also capable of generating progenitors which are either synthesized from these migrants or are direct recruits from other tissues. In the niches, the cells settle down and await their turn to either make more clones like themselves or differentiate and mobilize in an exigency. Thus progenitors are important reserves, to be multiplied and deployed or travel as important message bearing molecules via blood as circulating progenitors which can home to their allocated destinations. Upon reaching, specific integrins and selectins help them "dock" and "port" and they may be reprogrammed to induce further differentiation and help repopulate the denuded tissue. In pulmonary fibrosis and asthma, progenitors from both systemic circulation and local stem cell niches have been found to participate in the myriad ramifications of repair, replacement and regeneration of lost or diseased tissue. Whether they are lung specific or global in origin and role remain to be explored. Research tools, fundamental concepts, techniques, methodologies and standard operating protocols and animal models and human extrapolations, have been discussed in a concise way along with detailed description and discussion on the appropriate rationale to introduce the subject to the casual reader and provide valuable tactical information to the specialist in Regenerative Medicine. I sincerely hope you enjoy the work and appreciate the hard work that has gone into designing and executing elegant experiments by many researchers in the field. The branch is multi-disciplinary and I hope that the readers will not be limited to biologists alone.

Immunologic Signatures of Rejection (Paperback, 2011 ed.): Francesco M. Marincola, Ena Wang Immunologic Signatures of Rejection (Paperback, 2011 ed.)
Francesco M. Marincola, Ena Wang
R4,507 Discovery Miles 45 070 Ships in 10 - 15 working days

This book discusses the mechanisms leading to immune-mediated tissue rejection following the hypothesis that independent of the disease process the final effector mechanism is shared by most (but not all) pathologies and it is relatively simple. The book covers evidence gathered to support the thesis by studies performed in humans during rejection or in experimental models and will focus particularly (but not exclusively) on the analysis of the rejected tissue rather than the systemic circulation. Several disease processes are discussed including example of chronic inflammatory process without resolution of the pathologic process and acute one with resolution of the pathologic process (clearance of pathogen, rejection of tumor) or unwanted tissue destruction (allograft rejection, autoimmunity).

Immunologic Signatures of Rejection (Hardcover, 2011 Ed.): Francesco M. Marincola, Ena Wang Immunologic Signatures of Rejection (Hardcover, 2011 Ed.)
Francesco M. Marincola, Ena Wang
R4,572 Discovery Miles 45 720 Ships in 10 - 15 working days

This book discusses the mechanisms leading to immune-mediated tissue rejection following the hypothesis that independent of the disease process the final effector mechanism is shared by most (but not all) pathologies and it is relatively simple. The book covers evidence gathered to support the thesis by studies performed in humans during rejection or in experimental models and will focus particularly (but not exclusively) on the analysis of the rejected tissue rather than the systemic circulation. Several disease processes are discussed including example of chronic inflammatory process without resolution of the pathologic process and acute one with resolution of the pathologic process (clearance of pathogen, rejection of tumor) or unwanted tissue destruction (allograft rejection, autoimmunity).

Writer on the Run - German-Jewish Identity and the Experience of Exile in the Life and Work of Henry William Katz (Hardcover,... Writer on the Run - German-Jewish Identity and the Experience of Exile in the Life and Work of Henry William Katz (Hardcover, Reprint 2014)
Ena Pedersen
R4,266 Discovery Miles 42 660 Ships in 10 - 15 working days

This is the first academic treatment of the life and work of Henry William Katz (1906-1992) who has been forgotten by scholars and critics for fifty years although his first novel won him the Heinrich-Heine-Prize in exile in 1937. From a combined literary, historical, biographical and sociological perspective, Ena Pedersen analyses Katz's depiction on the Eastern European Jews in Galicia, Weimar Germany and in exile, focusing on the problems of anti-Semitism, assimilation, German-Jewish symbiosis, and Jewish identity. The book further provides a first biography of Katz and places him in the context of German exile literature through comparisons with contemporary Jewish and non-Jewish writers in exile.

Like Family - Domestic Workers In South African History And Literature (Paperback): Ena Jansen Like Family - Domestic Workers In South African History And Literature (Paperback)
Ena Jansen 1
R395 R309 Discovery Miles 3 090 Save R86 (22%) Ships in 5 - 10 working days

More than a million black South African women are domestic workers. These nannies, housekeepers and chars continue to occupy a central place in in postapartheid society. But it is an ambivalent position. Precariously situated between urban and rural areas, rich and poor, white and black, these women are at once intimately connected and at a distant remove from the families they serve. ‘Like family’ they may be, but they and their employers know they can never be real family.

Ena Jansen shows that domestic worker relations in South Africa were shaped by the institution of slavery at the Cape. This established social hierarchies and patterns of behaviour and interaction that persist to the present day, and are still evident in the predicament of the black female domestic worker.

To support her argument, Jansen examines the representation of domestic workers in a diverse range of texts in English and Afrikaans. Authors include Andr Brink, JM Coetzee, Imraan Coovadia, Nadine Gordimer, Elsa Joubert, Antjie Krog, Sindiwe Magona, Kopano Matlwa, Es’kia Mphahlele, Sisonke Msimang, Zukiswa Wanner and Zo Wicomb. Later texts by black authors offer wry and subversive insights into the madam/maid nexus, capturing paradoxes relating to shifting power relationships. Like Family is an updated version of the award-winning Soos familie published in 2015 and the highly-acclaimed 2016 Dutch translation, Bijna familie.

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