Even though he's not being honest, a bored shepherd boy thinks it's fun to see the villagers run to help him when he cries, "Wolf " Find out what happens when the villagers no longer believe what he says.

Basic topics and objects High frequency words Simple language patterns GRL: D-E
Familiar topics Frequently used words Repeating patterns GRL: F-G
New ideas Larger vocabulary Variety of language structures GRL: G-H
Challenges in ideas Expanding vocabulary Wide variety of sentences GRL: G-I
More complex ideas Extended vocabulary range Variety of language structures GRL: S-O
Wide range of concepts and ideas Challenging vocabulary Complex language structures GRL: N-P

Basic topics and objects High frequency words Simple language patterns GRL: D-E
Familiar topics Frequently used words Repeating patterns GRL: F-G
New ideas Larger vocabulary Variety of language structures GRL: G-H
Challenges in ideas Expanding vocabulary Wide variety of sentences GRL: G-I
More complex ideas Extended vocabulary range Variety of language structures GRL: S-O
Wide range of concepts and ideas Challenging vocabulary Complex language structures GRL: N-P

Basic topics and objects High frequency words Simple language patterns GRL: D-E
Familiar topics Frequently used words Repeating patterns GRL: F-G
New ideas Larger vocabulary Variety of language structures GRL: G-H
Challenges in ideas Expanding vocabulary Wide variety of sentences GRL: G-I
More complex ideas Extended vocabulary range Variety of language structures GRL: S-O
Wide range of concepts and ideas Challenging vocabulary Complex language structures GRL: N-P

The major histocompatibility complex (MHC) genes are involved in the immune system's response to tumor and infected cells and in generating an immune response. This book brings together basic aspects of the regulation of MHC antigens with important clinical applications (in viral infection, viral oncology, cancer biology and autoimmunity). There is a strong emphasis on situations where MHC expression is modulated (either stimulated or repressed). The book's major themes are: the mechanisms of MHC expression--explored at several levels including the transcription and translation of MHC genes and the insertion of MHC protein molecules into plasma membranes; the effect of cytokines on MHC expression--both in the etiology of certain diseases and in possible immunotherapeutic approaches to disease; and the use of gene therapy to modify MHC expression in cancer cells, and thereby cause tumor rejection. This book will be valuable to researchers and clinicians in molecular biology, immunology, oncology, and virology.

Basic topics and objects High frequency words Simple language patterns GRL: D-E
Familiar topics Frequently used words Repeating patterns GRL: F-G
New ideas Larger vocabulary Variety of language structures GRL: G-H
Challenges in ideas Expanding vocabulary Wide variety of sentences GRL: G-I
More complex ideas Extended vocabulary range Variety of language structures GRL: S-O
Wide range of concepts and ideas Challenging vocabulary Complex language structures GRL: N-P

A satiric re-telling of American history using farm animals together with shorter fables, both original and traditional.