This volume provides broad coverage of computational and mathematical techniques and concepts related to the field of comparative genomics. The topics covered in the chapters range from those concerned with general techniques and concepts that apply to all organisms to others that are more specialized, covering specific biological systems such as viruses, Drosophila, and Homo sapiens. Written in the highly successful Methods in Molecular Biology series format, by authors who are active researchers in the field, many chapters include step-by-step procedures, which illustrate practical applications of the techniques described. Cutting-edge and thorough, Comparative Genomics: Methods and Protocols should be useful to students and researchers in the continually growing and exciting field of comparative genomics.

This work is for scholars, researchers and students in history and philosophy of science focusing on Logical Empiricism and analytic philosophy (of science). It provides historical and systematic research and deals with the influence and impact of the Vienna Circle/Logical Empiricism on today's philosophy of science. It also explores the intellectual context of this scientific philosophy and focuses on main figures and peripheral adherents.

The articles in this volume deal with the main inferential methods that can be applied to different kinds of experimental evidence. These contributions - accompanied with critical comments - by renowned scholars in the field of philosophy of science aim at removing the traditional opposition between inductivists and deductivists. They explore the different methods of explanation and justification in the sciences in different contexts and with different objectives.
The volume contains contributions on methods of the sciences, especially on induction, deduction, abduction, laws, probability and explanation, ranging from logic, mathematics, natural to the social sciences. They present a highly topical pluralist re-evaluation of methodological and foundational procedures and reasoning, e.g. focusing in Bayesianism and Artificial Intelligence.
They document the second international conference in Vienna on "Induction and Deduction in the Sciences" as part of the Scientific Network on "Historical and Contemporary Perspectives of Philosophy of Science in Europe," funded by the European Science Foundation (ESF).

The present Volume 4 of the Vienna Circle Yearbook is dedicated to Otto Neurath, one of the leading figures of the Vienna Circle and one of last polymaths representative of the vanished culture from which the Circle emerged. Situating Neurath's work between the topoi of Encyclopedism - as a theoretical, scientific tool of the unfinished' project of (post-) enlightenment - and Utopianism - as the resolve to work for the systematic improvement of society and science - this volume presents the most recent research as well as critical and updated surveys and assessments of Neurath's many-faceted and impressive life work. The contributions range from history and philosophy of science, epistemology, sociology and economics to pictorial statistics (ISOTYPE) and museology. Special attention is given to Neurath's methodological holism and epistemological naturalism, as well as to the interrelations of the different disciplines in Neurath's conception of the Unity of Science. Most contributors agree that the historical and systematic reconstruction of Neurath's conception of science leads to issues of crucial relevance to the ongoing task of sharpening the instrument that is science for its responsible application in the natural and social world. The volume also includes Neurath's previously unpublished full manuscript on visual education, a report on archival holdings concerning Neurath's work and a review section focusing on recent publications on Neurath and Logical Empiricism. An overview of the activities of the Institute Vienna Circle 1996/97 concludes the volume. Audience: Philosophers in general, philosophers of science and historians of science, and sociologists. The book will alsointerest scholars specialized in adult education, museology and economics.

Constructibility and complexity play central roles in recent research in computer science, mathematics and physics. For example, scientists are investigating the complexity of computer programs, constructive proofs in mathematics and the randomness of physical processes. But there are different approaches to the explication of these concepts. This volume presents important research on the state of this discussion, especially as it refers to quantum mechanics. This foundational debate' in computer science, mathematics and physics was already fully developed in 1930 in the Vienna Circle. A special section is devoted to its real founder Hans Hahn, referring to his contribution to the history and philosophy of science. The documentation section presents articles on the early Philipp Frank and on the Vienna Circle in exile. Reviews cover important recent literature on logical empiricism and related topics.

This volume includes recent contributions to the philosophy of science from a historical point of view and of the highest topicality: the range of the topics covers all fields in the philosophy of the science provided by authors from around the world focusing on ancient, modern and contemporary periods in the development of the science philosophy. This proceedings is for the scientific community and students at graduate level as well as postdocs in this interdisciplinary field of research.

The articles in this volume deal with the main inferential methods that can be applied to different kinds of experimental evidence. These contributions - accompanied with critical comments - by renowned scholars in the field of philosophy of science aim at removing the traditional opposition between inductivists and deductivists. They explore the different methods of explanation and justification in the sciences in different contexts and with different objectives.
The volume contains contributions on methods of the sciences, especially on induction, deduction, abduction, laws, probability and explanation, ranging from logic, mathematics, natural to the social sciences. They present a highly topical pluralist re-evaluation of methodological and foundational procedures and reasoning, e.g. focusing in Bayesianism and Artificial Intelligence.
They document the second international conference in Vienna on "Induction and Deduction in the Sciences" as part of the Scientific Network on "Historical and Contemporary Perspectives of Philosophy of Science in Europe," funded by the European Science Foundation (ESF).

The present Volume 4 of the Vienna Circle Yearbook is dedicated to Otto Neurath, one of the leading figures of the Vienna Circle and one of last polymaths representative of the vanished culture from which the Circle emerged. Situating Neurath's work between the topoi of Encyclopedism - as a theoretical, scientific tool of the unfinished' project of (post-) enlightenment - and Utopianism - as the resolve to work for the systematic improvement of society and science - this volume presents the most recent research as well as critical and updated surveys and assessments of Neurath's many-faceted and impressive life work. The contributions range from history and philosophy of science, epistemology, sociology and economics to pictorial statistics (ISOTYPE) and museology. Special attention is given to Neurath's methodological holism and epistemological naturalism, as well as to the interrelations of the different disciplines in Neurath's conception of the Unity of Science. Most contributors agree that the historical and systematic reconstruction of Neurath's conception of science leads to issues of crucial relevance to the ongoing task of sharpening the instrument that is science for its responsible application in the natural and social world. The volume also includes Neurath's previously unpublished full manuscript on visual education, a report on archival holdings concerning Neurath's work and a review section focusing on recent publications on Neurath and Logical Empiricism. An overview of the activities of the Institute Vienna Circle 1996/97 concludes the volume. Audience: Philosophers in general, philosophers of science and historians of science, and sociologists. The book will also interest scholars specialized in adult education, museology and economics.

Scientific Philosophy: Origins and Development is the first Yearbook of the Vienna Circle Institute, which was founded in October 1991. The book contains original contributions to an international symposium which was the first public event to be organised by the Institute: `Vienna--Berlin--Prague: The Rise of Scientific Philosophy: The Centenaries of Rudolf Carnap, Hans Reichenbach and Edgar Zilsel.' The first section of the book - `Scientific Philosophy - Origins and Developments' reveals the extent of scientific communication in the inter-War years between these great metropolitan centres, as well as presenting systematic investigations into the relevance of the heritage of the Vienna Circle to contemporary research and philosophy. This section offers a new paradigm for scientific philosophy, one which contrasts with the historiographical received view of logical empiricism. Support for this re-evaluation is offered in the second section, which contains, for the first time in English translation, Gustav Bergmann's recollections of the Vienna Circle, and an historical study of political economist Wilhelm Neurath, Otto Neurath's father. The third section gives a report on current computer-based research which documents the relevance of Otto Neurath's `Vienna method of pictorial statistics', or `Isotypes'. A review section describes new publications on Neurath and the Vienna Circle, as well anthologies relevant to Viennese philosophy and its history, setting them in their wider cultural and political perspective. Finally, a description is given of the Vienna Circle Institute and its activities since its foundation, as well as of its plans for the future.

This work is for scholars, researchers and students in history and philosophy of science focusing on Logical Empiricism and analytic philosophy (of science). It provides historical and systematic research and deals with the influence and impact of the Vienna Circle/Logical Empiricism on today's philosophy of science. It also explores the intellectual context of this scientific philosophy and focuses on main figures and peripheral adherents.

Constructibility and complexity play central roles in recent research in computer science, mathematics and physics. For example, scientists are investigating the complexity of computer programs, constructive proofs in mathematics and the randomness of physical processes. But there are different approaches to the explication of these concepts. This volume presents important research on the state of this discussion, especially as it refers to quantum mechanics. This foundational debate' in computer science, mathematics and physics was already fully developed in 1930 in the Vienna Circle. A special section is devoted to its real founder Hans Hahn, referring to his contribution to the history and philosophy of science. The documentation section presents articles on the early Philipp Frank and on the Vienna Circle in exile. Reviews cover important recent literature on logical empiricism and related topics.

This volume includes recent contributions to the philosophy of science from a historical point of view and of the highest topicality: the range of the topics covers all fields in the philosophy of the science provided by authors from around the world focusing on ancient, modern and contemporary periods in the development of the science philosophy. This proceedings is for the scientific community and students at graduate level as well as postdocs in this interdisciplinary field of research.

Eigenvectors of graph Laplacians have not, to date, been the subject of expository articles and thus they may seem a surprising topic for a book. The authors propose two motivations for this new LNM volume: (1) There are fascinating subtle differences between the properties of solutions of Schrodinger equations on manifolds on the one hand, and their discrete analogs on graphs. (2) Geometric properties of (cost) functions defined on the vertex sets of graphs are of practical interest for heuristic optimization algorithms. The observation that the cost functions of quite a few of the well-studied combinatorial optimization problems are eigenvectors of associated graph Laplacians has prompted the investigation of such eigenvectors.

The volume investigates the structure of eigenvectors and looks at the number of their sign graphs ( nodal domains ), Perron components, graphs with extremal properties with respect to eigenvectors. The Rayleigh quotient and rearrangement of graphs form the main methodology."

Readers will find here a fascinating text that is the thoroughly refereed post-proceedings of the 9th Workshop on the Foundations of Genetic Algorithms, FOGA 2007, held in Mexico City in January 2007. The 11 revised full papers presented were carefully reviewed and selected during two rounds of reviewing and improvement from 22 submissions. The papers address all current topics in the field of theoretical evolutionary computation and also depict the continuing growth in interactions with other fields such as mathematics, physics, and biology

This book constitutes the refereed proceedings of the Brazilian Symposium on Bioinformatics, BSB 2021, held in November 2021. Due to COVID-19 pandemic the conference was held virtually The 10 revised full papers and 5 short papers were carefully reviewed and selected from 28 submissions. The papers address a broad range of current topics in computational biology and bioinformatics.