This is the first text to examine the use of statistical methods in forensic science and bayesian statistics in combination.

The book is split into two parts: Part One concentrates on the philosophies of statistical inference. Chapter One examines the differences between the frequentist, the likelihood and the Bayesian perspectives, before Chapter Two explores the Bayesian decision-theoretic perspective further, and looks at the benefits it carries.

Part Two then introduces the reader to the practical aspects involved: the application, interpretation, summary and presentation of data analyses are all examined from a Bayesian decision-theoretic perspective. A wide range of statistical methods, essential in the analysis of forensic scientific data is explored. These include the comparison of allele proportions in populations, the comparison of means, the choice of sampling size, and the discrimination of items of evidence of unknown origin into predefined populations.

Throughout this practical appraisal there are a wide variety of examples taken from the routine work of forensic scientists. These applications are demonstrated in the ever-more popular R language. The reader is taken through these applied examples in a step-by-step approach, discussing the methods at each stage.

Genetically determined myelinopathies are a large group of neurological diseases that present a challenge to the clinician, the biologist and the geneticist. During the last decade, the development of tools for exploring the nervous system and the human genome has had a tremendous impact on the understanding of these diseases. Thus, the advances in neuroimaging techniques and molecular genetic research are continuously influencing disease classification, diagnostic protocols, and management of patients. These topics are the focus of the present publication. The aim is to provide a comprehensive review of the most important issues regarding genetic myelin disorders.

"This book should have a place on the bookshelf of every forensic scientist who cares about the science of evidence interpretation" Dr. Ian Evett, Principal Forensic Services Ltd, London, UK Continuing developments in science and technology mean that the amounts of information forensic scientists are able to provide for criminal investigations is ever increasing. The commensurate increase in complexity creates difficulties for scientists and lawyers with regard to evaluation and interpretation, notably with respect to issues of inference and decision. Probability theory, implemented through graphical methods, and specifically Bayesian networks, provides powerful methods to deal with this complexity. Extensions of these methods to elements of decision theory provide further support and assistance to the judicial system. Bayesian Networks for Probabilistic Inference and Decision Analysis in Forensic Science provides a unique and comprehensive introduction to the use of Bayesian decision networks for the evaluation and interpretation of scientific findings in forensic science, and for the support of decision-makers in their scientific and legal tasks. Includes self-contained introductions to probability and decision theory. Develops the characteristics of Bayesian networks, object-oriented Bayesian networks and their extension to decision models. Features implementation of the methodology with reference to commercial and academically available software. Presents standard networks and their extensions that can be easily implemented and that can assist in the reader s own analysis of real cases. Provides a technique for structuring problems and organizing data based on methods and principles of scientific reasoning. Contains a method for the construction of coherent and defensible arguments for the analysis and evaluation of scientific findings and for decisions based on them. Is written in a lucid style, suitable for forensic scientists and lawyers with minimal mathematical background. Includes a foreword by Ian Evett. The clear and accessible style of this second edition makes this book ideal for all forensic scientists, applied statisticians and graduate students wishing to evaluate forensic findings from the perspective of probability and decision analysis. It will also appeal to lawyers and other scientists and professionals interested in the evaluation and interpretation of forensic findings, including decision making based on scientific information.