The QNP series of international conferences on Quarks and Nuclear Physics is by now a well established and highly respected forum where the most recent developments in the field are discussed and communicated. QNP 2006 is the forth edition of this biennial meeting. Selected and refereed original contributions of QNP 2006 have been published in The European Physical Journal A - Hadrons and Nuclei (EPJ A), while the present proceedings book, in addition to reprinting the articles published in EPJ A, further includes all other contributions selected and accepted by the organizing committee for publication and archiving.