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Featuring the work of several world authorities, this volume places
primary emphasis on the mechanism of parasite produced changes in
the immune response (i.e. immunosuppression). The text covers
parasitic diseases on which the World Health Organization has
aggressively promoted research through its Program on Research and
Training In Tropical Diseases. Chapters cover parasitic diseases
such as malaria, American trypanosomiasis (Chagas' disease),
African trypanosomiasis (sleeping sickness), leishmaniasis,
schistosomiasis and onchocerciasis. Also included are discussions
of toxoplasmosis and amebiasis. The material is drawn from the body
of literature that has been rapidly accumulating for the last 15
years. An important feature of this text is that the contributors
first outline existing knowledge about the immunology of each
infection, thereby enabling the reader to more easily appreciate
why and how the immunological alterations that accompany a disease
are important, and then, to review the postulated mechanisms for
such alterations. Consequently, the impact that each parasitic
infection has on the immune system is always described in the
"heart" of each chapter rather than at the beginning.
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