Understanding the functional roles of DNA modifications relies on the accurate detection, quantification, and mapping of DNA modifications. Methods for deciphering DNA modifications have substantially improved over the last several years, which greatly revolutionize the field of DNA modifications. In addition to DNA cytosine methylation (5-methylcytosine, 5mC), the best-characterized epigenetic modification, many new modifications have been discovered to present in DNA in recent years. This book provides a comprehensive overview of available techniques and methods together with detailed step-by-step protocols for experimental procedures required to successfully perform analysis on various types of DNA modifications, including 5mC, 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), 5-carboxycytosine (5caC), 5-hydroxymethyluracil (5hmU), 5-formyluracil (5fU), N6-methyladenine (6mA), -D-glucosyl-5-hydroxymethyluracil (base J) and 8-oxo-7,8-dihydroguanine (OG). This laboratory manual is a valuable source for biochemists and molecular biologists from different fields who wish to investigate DNA modifications.

Understanding the functional roles of DNA modifications relies on the accurate detection, quantification, and mapping of DNA modifications. Methods for deciphering DNA modifications have substantially improved over the last several years, which greatly revolutionize the field of DNA modifications. In addition to DNA cytosine methylation (5-methylcytosine, 5mC), the best-characterized epigenetic modification, many new modifications have been discovered to present in DNA in recent years. This book provides a comprehensive overview of available techniques and methods together with detailed step-by-step protocols for experimental procedures required to successfully perform analysis on various types of DNA modifications, including 5mC, 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), 5-carboxycytosine (5caC), 5-hydroxymethyluracil (5hmU), 5-formyluracil (5fU), N6-methyladenine (6mA), -D-glucosyl-5-hydroxymethyluracil (base J) and 8-oxo-7,8-dihydroguanine (OG). This laboratory manual is a valuable source for biochemists and molecular biologists from different fields who wish to investigate DNA modifications.

Applied Geochemistry: Advances in Mineral Exploration Techniques is a book targeting all levels of exploration geologists, geology students and geoscientists working in the mining industry. This reference book covers mineral exploration techniques from multiple dimensions, including the application of statistics - both principal component analysis and factor analysis - to multifractal modeling. The book explains these approaches step-by-step and gives their limitations. In addition to techniques and applications in mineral exploration, Applied Geochemistry describes mineral deposits and the theories underpinning their formation through worldwide case studies.

The global financial crisis of September 2008 highlighted the importance of financial stability, financial soundness, and currency stability. This dissertation contributes to the literature in these areas with two studies. The first essay examines the financial characteristics of banks that use derivatives and those that do not, as well as the relationship between the use of derivatives and financial characteristics using quarterly data from all domestic banks from March 1998 to March 2009. The second essay estimates the sensitivity of stock returns to market, interest and exchange rate risks of the Chinese and Taiwanese financial institutions, and it also examines the pricing of these risk factors in the framework of Ross' (1976) arbitrage pricing theory. The two-step estimation procedure adopts a seemingly unrelated regression method using daily data for the period from 21 July 2005 to 31 December 2009. Finally, the implications of these findings for regulators, industrialists and academicians are provided in this dissertation.