DNA Modification Detection Methods (Paperback, 1st ed. 2022)

Understanding the functional roles of DNA modifications relies on the accurate detection, quantification, and mapping of DNA modifications. Methods for deciphering DNA modifications have substantially improved over the last several years, which greatly revolutionize the field of DNA modifications. In addition to DNA cytosine methylation (5-methylcytosine, 5mC), the best-characterized epigenetic modification, many new modifications have been discovered to present in DNA in recent years. This book provides a comprehensive overview of available techniques and methods together with detailed step-by-step protocols for experimental procedures required to successfully perform analysis on various types of DNA modifications, including 5mC, 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), 5-carboxycytosine (5caC), 5-hydroxymethyluracil (5hmU), 5-formyluracil (5fU), N6-methyladenine (6mA), -D-glucosyl-5-hydroxymethyluracil (base J) and 8-oxo-7,8-dihydroguanine (OG). This laboratory manual is a valuable source for biochemists and molecular biologists from different fields who wish to investigate DNA modifications.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Series:	Springer Protocols Handbooks
Release date:	July 2022
First published:	2022
Editors:	Bi-Feng Yuan
Dimensions:	254 x 178mm (L x W)
Format:	Paperback
Pages:	194
Edition:	1st ed. 2022
ISBN-13:	978-1-07-161231-6
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Science & Mathematics > Biology, life sciences > General Books > Medicine > Nursing & ancillary services > Biomedical engineering > General Promotions
LSN:	1-07-161231-X
Barcode:	9781071612316

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