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Chemical Genomics and Proteomics (Paperback, 2nd edition): Ferenc Darvas, Andras Guttman, Gyoergy Dorman Chemical Genomics and Proteomics (Paperback, 2nd edition)
Ferenc Darvas, Andras Guttman, Gyoergy Dorman
R2,367 Discovery Miles 23 670 Ships in 12 - 19 working days

Since the publication of the pioneering first edition of Chemical Genomics and Proteomics more than seven years ago, the area of chemical genomics has rapidly expanded and diversified to numerous novel methods and subdisciplines, such as chemical glycomics and lipidomics. This second edition has been updated to uniquely reflect this interdisciplinary feature as well as the remarkable developments that have occurred. The new edition also covers innovative applications from cell biology to drug discovery to, more recently, clinical diagnostics and medical practice, which utilize the concepts of chemical genomics. The text provides an overview of the strategies and methodologies of chemical genomics, focusing on emerging technologies and recent applications in the areas of combination chemical genetics, toxicogenomics, drug chemical genomics and proteomics, and orthogonal chemical genetics. It describes the development and application of novel analytical methods used in lipodomics, such as steroidomics. The book also discusses biomarker discovery applications of microarray technologies using DNA, RNA, and protein and glycan arrays. Chapters cover further applications of biomolecular biomarkers for disease diagnosis, in small molecule drug R&D, and during therapeutic use of medicines. These include prognostic, disease specific, response (surrogate), and toxicity biomarkers. In addition, the text explores the principles of contemporary systems biology and genomics in experimental medicine-a new paradigm that demonstrates a network-oriented view and advanced statistical and informatics data management, opening the way toward personalized medicine. Finally, various in silico chemogenomics approaches are addressed for predicting binding of drug candidates to undesirable targets, which would help in designing better clinical candidates with fewer side effects. This new edition benefits a broad range of readers from industrial and academic researchers in drug discovery, medicinal chemistry, and molecular and cell biology to physicians in clinical diagnostics and students in related fields of study.

Flow Chemistry - Applications (Paperback, 2. rev. and exten. edition): Ferenc Darvas, Gyoergy Dorman, Volker Hessel, Steven V.... Flow Chemistry - Applications (Paperback, 2. rev. and exten. edition)
Ferenc Darvas, Gyoergy Dorman, Volker Hessel, Steven V. Ley; Contributions by Jesus Alcazar, …
R2,286 R1,825 Discovery Miles 18 250 Save R461 (20%) Ships in 10 - 15 working days

The fully up-dated edition of the two-volume work covers both the theoretical foundation as well as the practical aspects. A strong insight in driving a chemical reaction is crucial for a deeper understanding of new potential technologies. New procedures for warranty of safety and green principles are discussed. Vol. 1: Fundamentals.

Flow Chemistry - Fundamentals (Paperback, 2. rev. and exten. edition): Ferenc Darvas, Gyoergy Dorman, Volker Hessel, Steven V.... Flow Chemistry - Fundamentals (Paperback, 2. rev. and exten. edition)
Ferenc Darvas, Gyoergy Dorman, Volker Hessel, Steven V. Ley; Contributions by Andrea Adamo, …
R2,309 R1,848 Discovery Miles 18 480 Save R461 (20%) Ships in 10 - 15 working days

The fully up-dated edition of the two-volume work covers both the theoretical foundation as well as the practical aspects. Presenting the complete insight into driving a chemical reaction provides a deep understanding for new potential technologies. Updated overview on devices and new key concepts of experimental procedures. Vol. 2: Applications.

Chemical Genomics and Proteomics (Hardcover, 2nd edition): Ferenc Darvas, Andras Guttman, Gyoergy Dorman Chemical Genomics and Proteomics (Hardcover, 2nd edition)
Ferenc Darvas, Andras Guttman, Gyoergy Dorman
R5,823 Discovery Miles 58 230 Ships in 12 - 19 working days

Since the publication of the pioneering first edition of Chemical Genomics and Proteomics more than seven years ago, the area of chemical genomics has rapidly expanded and diversified to numerous novel methods and subdisciplines, such as chemical glycomics and lipidomics. This second edition has been updated to uniquely reflect this interdisciplinary feature as well as the remarkable developments that have occurred. The new edition also covers innovative applications from cell biology to drug discovery to, more recently, clinical diagnostics and medical practice, which utilize the concepts of chemical genomics. The text provides an overview of the strategies and methodologies of chemical genomics, focusing on emerging technologies and recent applications in the areas of combination chemical genetics, toxicogenomics, drug chemical genomics and proteomics, and orthogonal chemical genetics. It describes the development and application of novel analytical methods used in lipodomics, such as steroidomics. The book also discusses biomarker discovery applications of microarray technologies using DNA, RNA, and protein and glycan arrays. Chapters cover further applications of biomolecular biomarkers for disease diagnosis, in small molecule drug R&D, and during therapeutic use of medicines. These include prognostic, disease specific, response (surrogate), and toxicity biomarkers. In addition, the text explores the principles of contemporary systems biology and genomics in experimental medicine-a new paradigm that demonstrates a network-oriented view and advanced statistical and informatics data management, opening the way toward personalized medicine. Finally, various in silico chemogenomics approaches are addressed for predicting binding of drug candidates to undesirable targets, which would help in designing better clinical candidates with fewer side effects. This new edition benefits a broad range of readers from industrial and academic researchers in drug discovery, medicinal chemistry, and molecular and cell biology to physicians in clinical diagnostics and students in related fields of study.

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