In this international bestseller, father and advocate for Autism awareness Arthur Fleischmann blends his daughter Carly's own words with his story of getting to know his remarkable daughter--after years of believing that she was unable to understand or communicate with him.
At the age of two, Carly Fleischmann was diagnosed with severe autism and an oral motor condition that prevented her from speaking. Doctors predicted that she would never intellectually develop beyond the abilities of a small child. Carly remained largely unreachable through the years. Then, at the age of ten, she had a breakthrough.
While working with her devoted therapists, Carly reached over to their laptop and typed "HELP TEETH HURT," much to everyone's astonishment. Although Carly still struggles with all the symptoms of autism, she now has regular, witty, and profound conversations on the computer with her family and her many thousands of supporters online.
One of the first books to explore firsthand the challenges of living with autism, "Carly's Voice "brings readers inside a once-secret world in the company of an inspiring young woman who has found her voice and her mission

Notes Become Music: A Guidebook from the Viennese Piano Tradition addresses the many unwritten nuances of dynamics, articulation and agogics as an expression of fundamental principles of a common European musical language. It treats the score as an incomplete musical shorthand that outlines the compositional and interpretive imperatives implicit within it, drawing on historical records from the eighteenth and nineteenth centuries and detailed comparisons of works to underline the author's presentation of Viennese tradition. This book is not primarily concerned with questions of style or interpretation. Rather, it explains the many facets of musical notation that were taken for granted by composers who assumed a knowledge of the piano tradition of their day. Notes Become Music informs not only those students in countries where the central European music tradition is still unfamiliar, but also a younger generation of Europeans who have grown up without a living connection to their musical past.

This is the first book to present field studies on the application of subject-oriented business process management (S-BPM). Each case presents a specific story and focuses on an essential modeling or implementation issue, and most end with implications or suggestions for further studies. Significant variables and success factors are identified that were discovered during the respective study and lead to suggesting S-BPM novelties. For each case, the authors explain step-by-step how the story develops, and provide readers guidance by detailing the respective rationale. The studies covered are clustered according to three main S-BPM themes: Part I “Business Operation Support” documents approaches to the practical development of S-BPM solutions in various application domains and organizational settings, while Part II “Consultancy and Education Support” highlights cases that can help to train readers in S-BPM modeling and knowledge acquisition for S-BPM lifecycle iterations. It also refers to architecting S-BPM solutions for application cases based on hands-on experience. Part III “Technical Execution Support” focuses on concepts for utilizing specific theories and technologies to execute S-BPM models. It also addresses how to create reference models for certain settings in the field. Lastly, the appendix covers all relevant aspects needed to grasp S-BPM modeling and apply it based on fundamental examples. Its format reconciles semantic precision with syntactic rigor.>Addressing the needs of developers, educators and practitioners, this book will help companies to learn from the experiences of first-time users and to develop systems that fit their business processes, explaining the latest key methodological and technological S-BPM developments in the fields of training, research and application.

S-BPM stands for “subject-oriented business process management” and focuses on subjects that represent the entities (people, programs etc.) that are actively engaged in processes. S-BPM has become one of the most widely discussed approaches for process professionals. Its potential particularly lies in the integration of advanced information technology with organizational and managerial methods to foster and leverage business innovation, operational excellence and intra- and inter-organizational collaboration. Thus S-BPM can also be understood as a stakeholder-oriented and social business process management methodology. In this book, the authors show how S-BPM and its tools can be used in order to solve communication and synchronization problems involving humans and/or machines in an organization. All the activities needed in order to implement a business process are shown step by step; it starts by analyzing the problem, continues with modeling and validating the corresponding process, and finishes off by embedding the process into the organization. The final result is a workflow that executes the process without the need for any programming. To this end, in the first step a very simple process is implemented, which is subsequently extended and improved in “adaption projects,” because additional problems have to be solved. This approach reflects the organizational reality, in which processes must always be changed and adapted to new requirements. This is a hands-on book, written by professionals for professionals, with a clear and concise style, a wealth of illustrations (as the title suggests), and focusing on an ongoing example with a real industrial background. Readers who want to execute all the steps by themselves can simply download the S-BPM tool suite from the www.i2pm.net website.

Activities performed in organizations are coordinated via communication between the people involved. The sentences used to communicate are naturally structured by subject, verb, and object. The subject describes the actor, the verb the action and the object what is affected by the action. Subject-oriented Business Process Management (S-BPM) as presented in this book is based on this simple structure which enables process-oriented thinking and process modeling. S-BPM puts the subject of a process at the center of attention and thus deals with business processes and their organizational environment from a new perspective, meeting organizational requirements in a much better way than traditional approaches. Subjects represent agents of an action in a process, which can be either technical or human (e.g. a thread in an IT system or a clerk). A process structures the actions of each subject and coordinates the required communication among the subjects. S-BPM provides a coherent procedural framework to model and analyze business processes: its focus is the cooperation of all stakeholders involved in the strategic, tactical, and operational issues, sharing their knowledge in a networked structure. The authors illustrate how each modeling activity through the whole development lifecycle can be supported through the use of appropriate software tools. The presentation style focuses on professionals in industry, and on students specializing in process management or organizational modeling. Each chapter begins with a summary of key findings and is full of examples, hints, and possible pitfalls. An interpreter model, a toolbox, and a glossary summarizing the main terms complete the book. The web site www.i2pm.net provides additional software tools and further material.

F. Schweda and A. Kurtz: Regulation of Renin Release by Local and Systemic Factors M. Krauss and V. Haucke: Shaping Membranes for Endocytosis B.M. Jockusch and P.L. Graumann: The Long Journey: Actin on the Road to Pro- and Eukaryotic Cells B. Colsoul, R. Vennekens and B. Nilius: Transient Receptor Potential (TRP) Cation Channels in Pancreatic ss cells

Activities performed in organizations are coordinated via communication

between the people involved. The sentences used to communicate are naturally structured by subject, verb, and object. The subject describes the actor, the verb the action and the object what is affected by the action. Subject-oriented Business Process Management (S-BPM) as presented in this book is based on this simple structure which enables process-oriented thinking and process modeling.

S-BPM puts the subject of a process at the center of attention and thus

deals with business processes and their organizational environment from a new perspective, meeting organizational requirements in a much better way than traditional approaches. Subjects represent agents of an action in a process, which can be either technical or human (e.g. a thread in an IT system or a clerk). A process structures the actions of each subject and coordinates the required communication among the subjects. S-BPM provides a coherent procedural framework to model and analyze business processes: its focus is the cooperation of all stakeholders involved in the strategic, tactical, and operational issues, sharing their knowledge in a networked structure.

The authors illustrate how each modeling activity through the whole development lifecycle can be supported through the use of appropriate software tools. The presentation style focuses on professionals in industry, and on students specializing in process management or organizational modeling. Each chapter begins with a summary of key findings and is full of examples, hints, and possible pitfalls. An interpreter model, a toolbox, and a glossary summarizing the main terms complete the book. The web site www.i2pm.net provides additional software tools and further material."

The purpose of this book is to make the reader famliar with software engineering for distributed systems. Software engineering is a valuable discipline in the develop ment of software. The reader has surely heard of software systems completed months or years later than scheduled with huge cost overruns, systems which on completion did not provide the performance promised, and systems so catastrophic that they had to be abandoned without ever doing any useful work. Software engi neering is the discipline of creating and maintaining software; when used in con junction with more general methods for effective management its use does reduce the incidence of horrors mentioned above. The book gives a good impression of software engineering particularly for dis tributed systems. It emphasises the relationship between software life cycles, meth ods, tools and project management, and how these constitute the framework of an open software engineering environment, especially in the development of distrib uted software systems. There is no closed software engineering environment which can encompass the full range of software missions, just as no single flight plan, airplane or pilot can perform all aviation missions. There are some common activities in software engi neering which must be addressed independent of the applied life cycle or methodol ogy. Different life cycles, methods, related tools and project management ap proaches should fit in such a software engineering framework."

F. Schweda and A. Kurtz: Regulation of Renin Release by Local and Systemic Factors M. Krauss and V. Haucke: Shaping Membranes for Endocytosis B.M. Jockusch and P.L. Graumann: The Long Journey: Actin on the Road to Pro- and Eukaryotic Cells B. Colsoul, R. Vennekens and B. Nilius: Transient Receptor Potential (TRP) Cation Channels in Pancreatic ss cells

Reverse logistics concerns the integration of used and obsolete products back into the supply chain as valuable resources. Economic, marketing, and legislative drivers increasingly are leading companies to take back and recover their products after use. The arising product flows pose novel challenges for supply chain management.

This book addresses decision making in reverse logistics. It covers a wide range of aspects, related to distribution, production and inventory management, and supply chain management. For each topic, it highlights key managerial issues in real-life examples and explains which quantitative models are available for addressing them. By treating a broad range of issues in a unified way, the book offers the reader a comprehensive view on the field of reverse logistics.

Reviews of Physiology, Biochemistry and Pharmacology

Volume 160 2008

V. di Marzo: Endocannabinoids: Synthesis and Degradation

R. Rivera and J. Chun: Biological Effects of Lysophospholipids

S. J. O Meara, K. Rodgers, and C. Godson: Lipoxins: Update and Impact of Endogenous Pro-Resolution Lipid Mediators

R.K.P. Benninger, M. Hao, and D. Piston: Multi-photon Excitation Imaging of Dynamic Processes in Living Cells and Tissues

G. Schmitz and M. Grandl: Lipid Homeostasis in Macrophages Implications for Atherosclerosis

The international conference \Operations Research 2008," the annual meeting of the German Operations Research Society (GOR), was held at the University of Augsburg on September 3-5, 2008. About 580 p- ticipants from more than 30 countries presented and listened to nearly 400 talks on a broad range of Operations Research. The general subject \Operations Research and Global Business" str- ses the important role of Operations Research in improving decisions in the increasingly complex business processes in a global environment. The plenary speakers Morris A. Cohen (Wharton School) and Bernd Liepert (Executive Board of KUKA Robotics) addressed this subject. Moreover, one of the founders of Operations Research, Saul Gass (U- versity of Maryland), gave the opening speech on the early history of Operations Research. This volume contains 93 papers presented at the conference, selected by the program committee and the section chairs, forming a representative sample of the various subjects dealt with at Operations Research 2008. The volume follows the structure of the conference, with 12 sections, grouped into six \Fields of Applications" and six \Fields of Methods and Theory." This structure in no way means a separation of theory and application, which would be detrimental in Operations Research, but displays the large spectrum of aspects in the focus of the papers. Of course, most papers present theory, methods and applications together.

How do the bodies we inhabit affect our relationship with art? How does art affect our relationship to our bodies? T Fleischmann uses Felix Gonzáles-Torres’s artworks—piles of candy, stacks of paper, puzzles—as a path through questions of love and loss, violence and rejuvenation, gender and sexuality. From the back porches of Buffalo, to the galleries of New York and L.A., to farmhouses of rural Tennessee, the artworks act as still points, sites for reflection situated in lived experience. Fleischmann combines serious engagement with warmth and clarity of prose, reveling in the experiences and pleasures of art and the body, identity and community.

Reviews of Physiology, Biochemistry and Pharmacology

Volume 160 2008

V. di Marzo: Endocannabinoids: Synthesis and Degradation

R. Rivera and J. Chun: Biological Effects of Lysophospholipids

S. J. O'Meara, K. Rodgers, and C. Godson: Lipoxins: Update and Impact of Endogenous Pro-Resolution Lipid Mediators

R.K.P. Benninger, M. Hao, and D. Piston: Multi-photon Excitation Imaging of Dynamic Processes in Living Cells and Tissues

G. Schmitz and M. Grandl: Lipid Homeostasis in Macrophages - Implications for Atherosclerosis

Contents

Philip C. Sharpe, Rosemary S. Harrison, and David P. Fairlie: Amyloid Peptides and Proteins in Review. - Marilena Kampa, Artemissia-Phoebe Nifli, George Notas, Elias Castanas: Polyphenols and Cancer Cell Growth. - Michal Janitz: Assigning Functions to Genes The Main Challenge of the Post-Genomic Era. - Brigittte M. Jockusch, Kai Murk and Martin Rothkegel: The Profile of Profilins.

Contents

E.I. Christensen and R. Nielsen: Role of Megalin and Cubilin in Renal Physiology and Pathophysiology

G. Zifarelli and M. Pusch: CLC Chloride Channels and Transporters: A Biophysical and Physiological Perspective

S.F.J. van de Graaf, R.J.M. Bindels and J.G.J. Hoenderop: Physiology of Epithelial Ca2 and Mg2+ Transport

The complexity of distribution systems is augmented by various trends: globalization of the manufacturing industry, rising customer demands, and the reverse flows within closed-loop systems. In this light, the need for 'advanced' planning methods that are based on quantitative optimization is constantly increasing. This book takes up the challenges posed by these developments. In doing so, it presents recent results and case studies from a group of researchers that regularly meet at the IWDL (International Workshop on Distribution Logistics). The text covers the design of distribution networks, vehicle routing, warehousing and reverse logistics. It also contains a comprehensive review of more than 60 case studies in reverse logistics.

Reverse logistics concerns the integration of used and obsolete products back into the supply chain as valuable resources. Economic, marketing, and legislative drivers increasingly are leading companies to take back and recover their products after use. The arising product flows pose novel challenges for supply chain management.

This book addresses decision making in reverse logistics. It covers a wide range of aspects, related to distribution, production and inventory management, and supply chain management. For each topic, it highlights key managerial issues in real-life examples and explains which quantitative models are available for addressing them. By treating a broad range of issues in a unified way, the book offers the reader a comprehensive view on the field of reverse logistics.

Economic, marketing, and legislative considerations are increasingly leading companies to take back and recover their products after use. From a logistics perspective, these initiatives give rise to new goods flows from the user back to the producer. The management of these goods flows opposite to the traditional supply chain flows is addressed in the recently emerged field of Reverse Logistics. This monograph considers quantitative models that support decision making in Reverse Logistics. To this end, several recent case studies are reviewed. Moreover, first hand insight from a study on used electronic equipment is reported on. On this basis, logistics issues arising in the management of "reverse" goods flows are identified. Moreover, differences between Reverse Logistics and more traditional logistics contexts are highlighted. Finally, attention is paid to capturing the characteristics of Reverse Logistics in appropriate quantitative models.

This volume contains a selection of papers presented at the Symposium on Operations Research 2000 (OR 2000) held at the Dresden University of Technology, September 9-12, 2000. This international Symposium was organized by the German Operations Research Society GOR in the series of its annual conferences. The Symposium had 354 participants from IS countries around the world. The 210 lectures reflected the broad spectrum of Operations Research and its interdisciplinarity, involving economics, mathematics and computer science. The volume is arranged in 14 Sections, like the conference, and a special section with the papers of the winners of the GOR Diploma Thesis award. The 86 papers have been selected by the chairpersons of the sections and the editors. Compared to previous conferences, the number of sections has been reduced by combining some overlapping sections: The former sections for linear and nonlinear programming are now contained in the 'Continuous Optimization' Section, the graph theory has been included in the 'Discrete and Combinatorial Optimization' Section. The traditional application fields are growing together in the scope of the current 'Supply Chain Management' thinking. This is considered in a corresponding section. Its high number of papers at the conference and in this volume underlines the importance of Operations Research for this modem management concept. For the first time, the conference included a section on 'Didactics of Operations Research', which found a great echo and is represented by four papers in this volume.

Canon Sheehan's writings provide valuable insight into Ireland's difficult process of cultural reconstruction after independence. This astute observer of Irish society was pessimistic about the future of religion. Though himself a man of European culture, he made a case for the isolationism to become reality under the Free State. It is a case which today is easily scorned - but his works allow us to understand why it could command such support, and to appreciate its relative historical justification.

Vom 22.-24. September fand die 11. Jahrestagung der Deutschen Gesellschaft fOr Operations Research in den Raumen der Universitat Frankfurt statt.Mehr als 400 Teilnehmer folgten der Einladung der DGOR und diskutierten die neuesten metho- dischen Entwicklungslinien sowie ihre aktuellen Anwendungserfahrungen auf den unterschiedlichsten Gebieten des Operations Research. Der Charakter der einzelnen DGOR-Tagungen wird sehr stark durch das seit Jahren bewahrte Organisationsprinzip gepragt, Themenschwerpunkte in einzelnen Sektionen zu behandeln, die von Sektionsleitern weitgehend eigenverantwortlich geplant werden. Deren Engagement bestimmt zu einem groBen Teil Inhalt und Umfang der einzelnen Themenschwerpunkte. Ihnen gebOhrt fOr das Gelingen der Tagung herzlichen Dank. Einen Schwerpunkt auf der diesjahrigen DGOR-Tagung bildeten Fragen der Anwendung von Verfahren des Operations Research auf betriebswirtschaftliche Fragestellungen. 11 von 18 Sektionen waren diesem Problemkreis gewidmet. Die traditionellen methodisch orientierten Sektionen "Stetige Optimierung", "Diskrete Optimierung", "Entscheidungstheorie" und "Stochastische Entscheidungspro- zesse" formten den zweiten Schwerpunkt. In den beiden Sektionen "OR in der Datenverarbeitung" und "Angewandte Statistik" erfolgte eine Diskussion von Grenzgebieten, die einen erheblichen EinfluB auf die Formulierung und Losung von Problemen des Operations Research besitzen. Erstmals wurde in diesem Jahr ein Wettbewerb fOr Diplomarbeiten ausgeschrie- ben. Von 15 eingereichten Arbeiten wurden 4 pramiert. Die Preistrager prasentier- ten ihre Ergebnisse in einer eigenen Sektion.

Reminiscent of Edmund White's Nocturne for the King of Naples Fleischmann has had notable essays in Best American Essays 2009 and 2010 Author is a nonfiction editor for DIAGRAM and deeply plugged into the lyric essay world Appeals to the same audience as Maggie Nelson's celebrated Bluets and features a very enthusiastic blurb from her (there's already bookseller excitement about this) Fleischmann may be picked up for a column on Bookslut, which is an ideal venue for bringing broader attention to his facility for the kind of smart, plainspoken criticism in Syzygy The book represents Sarabande's ongoing commitment to developing a creative nonfiction list of depth, innovation, and energy not found anywhere else

Die Jahrestagung 1979 der Deutschen Gesellschaft fur Operations Research fand vom 19. bis 21. September 1979 in Regensburg statt. Die von annahernd 400 Teilnehmern besuchte Tagung bot in 125 Vortragen nicht nur einen Oberblick uber neueste Forschungsergebnisse auf den meisten methodischen Gebieten des Opera- tions Research, sondern auch einen intensiven Einblick in die vielfaltigen Anwendungsbereiche. Ebenso wie auf der Jahrestagung 1978 in Berlin wurde auch dieses Mal das Programm in Sektionen aufgeteilt. Diese Einteilung in Sektionen bot besonders gute Moglichkeiten einer vertiefenden Fachdiskussion und eines intensiven Erfahrungs- austausches mit angesehenen Fachvertretern und Experten. Den fur die wissen- schaftliche Betreuung der Sektionen verantwortlichen Sektionsleitern war es insbe- sondere zu verdanken, dass die Tagung ein so fundiertes und breites Programm bieten konnte und dass zu den Fachbeitragen der meisten Sektionen ein einfuhrendes Ubersichtsreferat gehalten wurde. Die Proceedings sollen einen Oberblick uber das wissenschaftliche Programm der Tagung geben. Wegen des begrenzten Raumes konnten nicht alle Vortrage in die Proceedings aufgenommen werden und bei einigen Vortragen erfolgte eine Beschrankung auf eine Zusammenfassung des Inhalts. Die meisten Fachbeitrage konnen dem interessierten Leser jedoch in ausfuhrlicher Fassung zuganglich gemacht werden. Den Referenten, den Sitzungsleitern und den Sektionsleitern ist fur ihren Anteil an der Gestaltung des Tagungsprogramms und der Proceedings zu danken. Besonderer Dank gebuhrt Herrn Prof. Dr. H. Steckhan und seinen Mitarbeitern, die in der Universitat und in der Stadt Regensburg einen ausgezeichneten Rahmen fur die Tagung geschaffen haben.

Notes Become Music: A Guidebook from the Viennese Piano Tradition addresses the many unwritten nuances of dynamics, articulation and agogics as an expression of fundamental principles of a common European musical language. It treats the score as an incomplete musical shorthand that outlines the compositional and interpretive imperatives implicit within it, drawing on historical records from the eighteenth and nineteenth centuries and detailed comparisons of works to underline the author's presentation of Viennese tradition. This book is not primarily concerned with questions of style or interpretation. Rather, it explains the many facets of musical notation that were taken for granted by composers who assumed a knowledge of the piano tradition of their day. Notes Become Music informs not only those students in countries where the central European music tradition is still unfamiliar, but also a younger generation of Europeans who have grown up without a living connection to their musical past.