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Optical Biosensors, 2ed describes the principles of successful
systems, examples of applications, and evaluates the advantages and
deficiencies of each. It also addresses future developments on two
levels: possible improvements in existing systems and emerging
technologies that could provide new capabilities in the future. The
book is formatted for ease of use and is therefore suitable for
scientists and engineers, students and researcher at all levels in
the field.
Biomolecules and cells are critical components of biosensors and biomaterials, but in order to function in an artificial environment, they must be immobilized in a manner that does not affect their interaction with target analytes. Biosensors demonstrate that we can harness the incredible functions of living molecules and cells for our own purposes and are therefore at the forefront of technology. Moreover the applications of immobilized biomolecules and cells are expected to expand far beyond biosensor applications and indeed are already used for pharmaceutical production and testing. Biomaterials will become increasing common as they are being developed into toxic filters, artificial organs, and even silicon chips. This text includes a selection of methods for the immobilization of biomolecules and cells on a variety of surface with different geometries and chemistries so that they retain their function and guidelines on which method to use. Also included are the analytical techniques to measure the functionality of immobilized biomolecules. All the protocols have been tried and validated by the authors. This book is intended for researchers at all levels involved in developing b
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