Somatic genome manipulation is required when a sexual crossing approach cannot be used in breeding or genetic treatment of an individual organism. Examples can include gene- or cell-therapy of a person to correct disease, genetic improvement of vegetatively propagated plants, and genetic replacement of cytoplasm without significantly modifying the nuclear genome. The advantage of somatic genome manipulation is maintenance of the general genotype while correcting one or more traits. Somatic genome manipulation is also an option for genetic improvement of sexually propagated plants in polyploidy breeding or in overcoming issues of sexual incompatibility. Recent novel technologies in somatic genome manipulation are developing quickly but much of this literature is fragmented and difficult or inconvenient to access. This book represents the first attempt to assemble updated reviews, detailed protocols, and their applications in all fields in which somatic genome manipulation has thrived. This is a truely one-of-a-kind work that brings together the most important and relevant advances in somatic genome manipulation in plants, algae, microorganisms, humans and animals, and demonstrates where the science interacts and where it diverges. The chapters are written by experts on the topic with ready-to-use protocols that were originally developed or adapted from the literature in their laboratories. We expect that this book will be useful for students, researchers, and teachers in both plant and animal research as a resource for the latest information on somatic genome manipulation and for its useful laboratory methods.

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An intensive global search is on for the "rule of law," the holy grail of good governance, which has led to a dramatic increase in judicial reform activities in developing countries. Very little attention, however, has been paid to the widening gap between theory and practice, or to the ongoing disconnect between stated project goals and actual funded activities.
"Beyond Common Knowledge" examines the standard methods of legal and judicial reform. Taking stock of international experience in legal and judicial reform in Latin America, Europe, India, and China, this volume answers key questions in the judicial reform debate: What are the common assumptions about the role of the courts in improving economic growth and democratic politics? Do we expect too much from the formal legal system? Is investing in judicial reform projects a good strategy for getting at the problems of governance that beset many developing countries? If not, what are we missing?

Somatic genome manipulation is required when a sexual crossing approach cannot be used in breeding or genetic treatment of an individual organism. Examples can include gene- or cell-therapy of a person to correct disease, genetic improvement of vegetatively propagated plants, and genetic replacement of cytoplasm without significantly modifying the nuclear genome. The advantage of somatic genome manipulation is maintenance of the general genotype while correcting one or more traits. Somatic genome manipulation is also an option for genetic improvement of sexually propagated plants in polyploidy breeding or in overcoming issues of sexual incompatibility. Recent novel technologies in somatic genome manipulation are developing quickly but much of this literature is fragmented and difficult or inconvenient to access. This book represents the first attempt to assemble updated reviews, detailed protocols, and their applications in all fields in which somatic genome manipulation has thrived. This is a truely one-of-a-kind work that brings together the most important and relevant advances in somatic genome manipulation in plants, algae, microorganisms, humans and animals, and demonstrates where the science interacts and where it diverges. The chapters are written by experts on the topic with ready-to-use protocols that were originally developed or adapted from the literature in their laboratories. We expect that this book will be useful for students, researchers, and teachers in both plant and animal research as a resource for the latest information on somatic genome manipulation and for its useful laboratory methods.

"When I find a short seller, I want to tear his heart out and eat it before his eyes while he's still alive." That's Dick Fuld, the high-commanding former CEO of the now-defunct Lehman Brothers (founded in 1850)... Before the Great Recession, Fuld's chief risk officer at Lehman Brothers issued a warning about the "sense of complacency" regarding risk. Two months later, the bull-in-the-china-shop Fuld gored his own risk officer. Fuld sacked her because he was unable or unwilling to address THE EXECUTIVE'S PARADOX. In fact, Fuld failed to stretch when he was pulled by two distinct paradoxes - one leadership and one strategic... Instead of managing the tension between his commanding leadership style (take-charge drill sergeant) AND his empowering style (take-care servant leader), Fuld's drill sergeant always won the tug-of-war. In addition, Fuld also failed to manage a strategic paradox - the one most responsible for the Great Recession: increasing profits AND mitigating risk... --- Unfortunately, Fuld is not the great exception of what happens when leaders mismanage THE EXECUTIVE'S PARADOX, he is the great example. Fuld has a lot of company. Consider... 1... Toyota, long the high-flyer in the auto industry, crashed and lost $2.5 billion more than General Motors during the Great Recession. Toyota leaders over-focused on growth instead of managing the tension between growth AND quality. 2... Boeing's innovative 787 aircraft, the Dreamliner, was more than three years late and billions of dollars over budget because executives mismanaged the stability AND change paradox. 3... High-tech guru Geoffrey Moore points out that many former technology giants, such as Digital Equipment Corporation, Silicon Graphics, and Wang, lost their way because they failed to stretch when pulled by today's realities AND tomorrow's dreams. --- These anecdotes are the tip of the iceberg. There is a mass of evidence below the surface demonstrating that leaders who fail to manage THE EXECUTIVE'S PARADOX fail to lead. One study of 1,000 organizations over a 20-year period discovered that 45 out of every 100 executives suffered sinking profits because they mismanaged their paradoxes... If you ever feel like you're paddling down a raging river with crowds of demanding stakeholders on opposite riverbanks, all shouting at you to paddle to their side at the same time, this book is for you. --- THE EXECUTIVE'S PARADOX teaches you how to avoid picking sides when you're pulled by opposing leadership and strategic demands. You learn stretch, not snap, as you develop new, business-boosting skills, such as how to::: A --- Expand your long-term, strategic thinking AND deliver short-term, bottom-line results. B --- Gain buy-in to any change AND build a platform of stability. C --- Demand accountability for results AND increase employee engagement. D --- Innovate by exploring the future AND optimize by exploiting the present. --- DAVID JENSEN knows your leadership challenges because he faced them when he was an executive. He understands that you have many options to deal with your challenges because he's studied them as a researcher. Dave delivers proven tools that get results because he's tested what works with over 10,000 leaders. Isn't it time to put his decades of leadership experience to work for you? - When you purchase THE EXECUTIVE'S PARADOX, you also are also buying access to the 360 assessment - THE EXPANSIVE LEADERSHIP MODEL tm (XLM) at no extra charge. Your book gives you the website, where you can complete the assessment FREE. After you complete the assessment, you can download XLM 25-page report for free too. Your report provides your scores (and other raters' scores, if you choose to invite them to rate you) on each 16 core competencies described in the book. - Thus, you get the book and the XLM 360 leadership assessment all for one low price. Isn't time to turbo charge your leadership skills now?