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Compendium Of In Vivo Monitoring In Real-time Molecular Neuroscience - Volume 2: Microdialysis And Sensing Of Neural Tissues... Compendium Of In Vivo Monitoring In Real-time Molecular Neuroscience - Volume 2: Microdialysis And Sensing Of Neural Tissues (Hardcover)
George S. Wilson, Adrian C. Michael
R4,534 Discovery Miles 45 340 Ships in 12 - 17 working days

Volume 1 of this series focused mainly on small molecules which are intrinsically electroactive. Volume 2 continues to provide current approaches to real time measurements of essential species in the central nervous system. It describes microdialysis, a sampling technique, which facilitates the removal of small volumes of solution containing the analyte(s) of interest which can be subsequently separated by chromatography and analyzed by a range of techniques. These include electrochemistry, UV-Vis spectroscopy, fluorescence and mass spectroscopy. This approach affords the opportunity to measure a range of targets in real-time thus providing access to pharmacokinetic/pharmacodynamics measurements affording the possibility of measuring the disappearance of a drug after administration and the subsequent appearance of metabolites. Microdialysis further affords the ability to sample peptides and proteins of neurobiological interest.Consistent with the goals of Volume 1, Volume 2 seeks to provide for scientists in the field of neurobiology a base of bioanalytical techniques that may not be familiar to them. Specific examples are provided and the fundamental basis of the technique is also covered.

Compendium Of In Vivo Monitoring In Real-time Molecular Neuroscience - Volume 1: Fundamentals And Applications (Hardcover):... Compendium Of In Vivo Monitoring In Real-time Molecular Neuroscience - Volume 1: Fundamentals And Applications (Hardcover)
George S. Wilson, Adrian C. Michael
R4,238 Discovery Miles 42 380 Ships in 12 - 17 working days

This new volume documents the transition from the development of electrochemical monitoring of brain function, now more than 40 years old, to fundamental neuroscience. This includes the links of molecular neuroscience to biobehavior, to a molecular understanding of neurologically-linked diseases and to the investigation of neuroactive molecules made possible by new detection methodology. This work should be of interest to a broad audience, especially those who are engaged in neuroscience research, for example in drug discovery, but are not familiar with electrochemical methodology.

Compendium Of In Vivo Monitoring In Real-time Molecular Neuroscience - Volume 3: Probing Brain Function, Disease And Injury... Compendium Of In Vivo Monitoring In Real-time Molecular Neuroscience - Volume 3: Probing Brain Function, Disease And Injury With Enhanced Optical And Electrochemical Sensors (Hardcover)
George S. Wilson, Adrian C. Michael
R4,788 Discovery Miles 47 880 Ships in 10 - 15 working days

This book is the third in a series entitled, Compendium of In-Vivo Monitoring in Real-time Molecular Neuroscience. Its purpose is to provide a cross-section of research addressing monitoring in the rodent, and in some cases, the human brain.Detailed understanding of the neurobiology of the brain is demanding and involves increasingly wider scope of talent ranging from physicists, neurobiologists, chemists, molecular biologists and bioengineers. Coming from varied backgrounds, they do not necessarily understand how to formulate functional issues in a mutually understandable way. This aim of this book is to provide information which can serve as a starting point for understanding such a complex topic.The authors provide 'tutorial' writing for specialists, as well as material understandable to a wide audience including neuroscientists, those interested in drug discovery, and those using such measurements for diagnosis purposes.

Destination Zion (Paperback): George S Wilson Jr Destination Zion (Paperback)
George S Wilson Jr
R491 R415 Discovery Miles 4 150 Save R76 (15%) Ships in 10 - 15 working days
Oration Delivered on the Sixty-Third Anniversary of American Independence... (Paperback): George S. Wilson Oration Delivered on the Sixty-Third Anniversary of American Independence... (Paperback)
George S. Wilson
R362 R295 Discovery Miles 2 950 Save R67 (19%) Ships in 10 - 15 working days
The Army - Its Employment During Time of Peace, and the Necessity for Its Increase (1898) (Paperback): George S. Wilson The Army - Its Employment During Time of Peace, and the Necessity for Its Increase (1898) (Paperback)
George S. Wilson
R530 Discovery Miles 5 300 Ships in 10 - 15 working days

This scarce antiquarian book is a selection from Kessinger Publishing's Legacy Reprint Series. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment to protecting, preserving, and promoting the world's literature. Kessinger Publishing is the place to find hundreds of thousands of rare and hard-to-find books with something of interest for everyone

The Army - Its Employment During Time Of Peace, And The Necessity For Its Increase (1898) (Paperback): George S. Wilson The Army - Its Employment During Time Of Peace, And The Necessity For Its Increase (1898) (Paperback)
George S. Wilson
R530 Discovery Miles 5 300 Ships in 10 - 15 working days
Compendium Of In Vivo Monitoring In Real-time Molecular Neuroscience - Volume 1: Fundamentals And Applications (Hardcover):... Compendium Of In Vivo Monitoring In Real-time Molecular Neuroscience - Volume 1: Fundamentals And Applications (Hardcover)
George S. Wilson, Adrian C. Michael
R10,753 R8,806 Discovery Miles 88 060 Save R1,947 (18%) Out of stock

This new volume documents the transition from the development of electrochemical monitoring of brain function, now more than 40 years old, to fundamental neuroscience. This includes the links of molecular neuroscience to biobehavior, to a molecular understanding of neurologically-linked diseases and to the investigation of neuroactive molecules made possible by new detection methodology. This work should be of interest to a broad audience, especially those who are engaged in neuroscience research, for example in drug discovery, but are not familiar with electrochemical methodology.

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