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G. F. FUEGER Among the many processes in Physiology few appear mo e
inviting to be studied by tracers and external imaging than the
variety of the routes of migratory (blood) cells in health and
disease. Much emphasis has been placed lately on the methods of
labelling of the white blood cells. It is obviously quite important
and necessary to refine the methods of leucocytic labelling,
particularly to search for ways to label selectively a specific
group of white blood cells, but there is also the need to review
and keep abreast with the developing knowledge of the white blood
cells themselves, especially their behaviour under pathological
conditions, as seen by histology and scintigraphy, their biological
properties, their immunological characteristics and the mechanisms
of the control of leucocytic functions. Similarly, it appears
desirable to analyze animal models of inflammation as well as to
review the dosimetry and the biodistribution of labelled white
blood cells in humans. This book is the result of a cooperative
effort to review certain highlights of the physiology of
leucocytes, labelled and unlabelled, as a corollary to the effort
concerning the labelling of white blood cells. In preparing this
book we aim for a better understanding and definition of the goals
to be achieved by the successful labelling of the migratory cells
of the body. XI CONTRIBUTORS Becker, H. Medizinische
Universitaetsklinik der Uni versitaet Graz, Graz,
Landeskrankenhaus, haus, Austria Bjurman, B. Department of
Radiation Physics, General Hospital, Malmoe, Sweden Chiles, C."
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