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The 11th international Conference on ADVANCES IN PROSTAGLANDIN AND
LEUKOTRIENE RESEARCH: BASICSCIENCEANDNEWCLlNICALApPLlCA TIONS was
held, as in the past, in Florence, Italy, on June 4-8, 2000. A
selection of lectures presented at the meeting is included in this
volume, which continues the tradition of covering both basic and
clinical aspects of prostaglandin and leukotriene research. At this
meeting particular emphasis was given to the lipid mediator
circuits of lipoxin and leukotrienes and to the expression ofthe
COX2 gene. The plenary lectures by C.N. Serhan (Boston,
Massachusetts, U.S.A.) and H.R. Herschman (Los Angeles, California,
U.S.A.) were devoted to these areas, while S. Narumiya (Kyoto,
Japan) and J.M. Drazen (Boston, Massachusetts, U.S.A.) presented
the latest advances in the fields ofprostanoid receptors and the
genetics of asthma. Specific sessions focused on vascular
physiopathology, cell differentiation and cancer, and the
cardiovascular system. Lipoxygenases were discussed in detail at
the molecular and cellular levels and attention was given to signal
transduction pathways for leukotrienes and prostanoids. K.F. Austen
(Boston, Massachusetts, U.S.A.) and T. Izumi (Tokyo, Japan)
clarified the role and regulation ofLTC synthase ofleukotriene
biosynthesis. Other important sessions 4 described regulation and
control of nitric oxide, cannabimimetic eicosanoids, and the roles
of eicosanoids in neuroscience. Applied clinical sessions devoted
to the respiratory system and inflammation, including
cyclooxygenase pathways, concluded the meeting.
Many new antileukotriene drugs are now marketed as antiasthma drugs
and represent the first new drugs in this field since the 1970s.
This book covers the steps that have led to the discovery and
development of these new drugs and offers detailed descriptions of
their clinical applications. The review chapters on the main
aspects of basic and applied leukotriene research are written by
leading specialists in the field, and the volume takes a new
approach in presenting information of particular interest to both
scientists and clinicians in the fields of asthma, inflammation and
allergic diseases.
Many new antileukotriene drugs are now marketed as antiasthma drugs
and represent the first new drugs in this field since the 1970s.
This book covers the steps that have led to the discovery and
development of these new drugs and offers detailed descriptions of
their clinical applications. The review chapters on the main
aspects of basic and applied leukotriene research are written by
leading specialists in the field, and the volume takes a new
approach in presenting information of particular interest to both
scientists and clinicians in the fields of asthma, inflammation and
allergic diseases.
The 11th international Conference on ADVANCES IN PROSTAGLANDIN AND
LEUKOTRIENE RESEARCH: BASICSCIENCEANDNEWCLlNICALApPLlCA TIONS was
held, as in the past, in Florence, Italy, on June 4-8, 2000. A
selection of lectures presented at the meeting is included in this
volume, which continues the tradition of covering both basic and
clinical aspects of prostaglandin and leukotriene research. At this
meeting particular emphasis was given to the lipid mediator
circuits of lipoxin and leukotrienes and to the expression ofthe
COX2 gene. The plenary lectures by C.N. Serhan (Boston,
Massachusetts, U.S.A.) and H.R. Herschman (Los Angeles, California,
U.S.A.) were devoted to these areas, while S. Narumiya (Kyoto,
Japan) and J.M. Drazen (Boston, Massachusetts, U.S.A.) presented
the latest advances in the fields ofprostanoid receptors and the
genetics of asthma. Specific sessions focused on vascular
physiopathology, cell differentiation and cancer, and the
cardiovascular system. Lipoxygenases were discussed in detail at
the molecular and cellular levels and attention was given to signal
transduction pathways for leukotrienes and prostanoids. K.F. Austen
(Boston, Massachusetts, U.S.A.) and T. Izumi (Tokyo, Japan)
clarified the role and regulation ofLTC synthase ofleukotriene
biosynthesis. Other important sessions 4 described regulation and
control of nitric oxide, cannabimimetic eicosanoids, and the roles
of eicosanoids in neuroscience. Applied clinical sessions devoted
to the respiratory system and inflammation, including
cyclooxygenase pathways, concluded the meeting.
L alimentazione nessuno pu negarlo un argomento che davvero
riguarda chiunque: per questa ragione importante mantenersi
aggiornati sui contributi sempre nuovi che accrescono le conoscenze
in quest ambito. Mangiare non una semplice abitudine, bens l
occasione per costruirsi un proprio programma alimentare mirato,
che uno dei modi pi efficaci per migliorare la qualit della vita,
ridurre il rischio di patologie gravi e favorire un sano processo
di invecchiamento. Questo volume ha l obiettivo di stimolare il
consumatore in questo processo di aggiornamento ricorrendo ad un
approccio multidisciplinare (che raccoglie le competenze del
chimico, del nutrizionista e del farmacologo) e ad un linguaggio
semplice e sintetico, elementi che insieme garantiscono un
informazione esauriente e rigorosa sulle opportunit offerte oggi
dal settore dell alimentazione.
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