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Bioreactors: Animal Cell Culture Control for Bioprocess Engineering
presents the design, fabrication, and control of a new type of
bioreactor meant especially for animal cell line culture. The new
bioreactor, called the "see-saw bioreactor," is ideal for the
growth of cells with a sensitive membrane. The see-saw bioreactor
derives its name from its principle of operation in which liquid
columns in either limb of the reactor alternately go up and down.
The working volume of the reactor is small, to within 15 L.
However, it can easily be scaled up for large production in volume
of cell mass in the drug and pharmaceutical industries. The authors
describe the principle of operation of the see-saw bioreactor and
how to automatically control the bioprocess. They discuss different
control strategies as well as the thorough experimental research
they conducted on this prototype bioreactor in which they applied a
time delay control for yield maximization. To give you a complete
understanding of the design and development of the see-saw
bioreactor, the authors cover the mathematical model they use to
describe the kinetics of fermentation, the genetic algorithms used
for deriving the optimal time trajectories of the bioprocess
variables, and the corresponding control inputs for maximizing the
product yield. One chapter is devoted to the application of time
delay control. Following a description of the bioreactor's working
setup in the laboratory, the authors sum up their investigation and
define the future scope of work in terms of design, control, and
software sensors.
Bioreactors: Animal Cell Culture Control for Bioprocess Engineering
presents the design, fabrication, and control of a new type of
bioreactor meant especially for animal cell line culture. The new
bioreactor, called the "see-saw bioreactor," is ideal for the
growth of cells with a sensitive membrane. The see-saw bioreactor
derives its name from its principle of operation in which liquid
columns in either limb of the reactor alternately go up and down.
The working volume of the reactor is small, to within 15 L.
However, it can easily be scaled up for large production in volume
of cell mass in the drug and pharmaceutical industries. The authors
describe the principle of operation of the see-saw bioreactor and
how to automatically control the bioprocess. They discuss different
control strategies as well as the thorough experimental research
they conducted on this prototype bioreactor in which they applied a
time delay control for yield maximization. To give you a complete
understanding of the design and development of the see-saw
bioreactor, the authors cover the mathematical model they use to
describe the kinetics of fermentation, the genetic algorithms used
for deriving the optimal time trajectories of the bioprocess
variables, and the corresponding control inputs for maximizing the
product yield. One chapter is devoted to the application of time
delay control. Following a description of the bioreactor's working
setup in the laboratory, the authors sum up their investigation and
define the future scope of work in terms of design, control, and
software sensors.
This book contains the latest research work presented at the
International Conference on Computing and Communication Systems
(I3CS 2020) held at North-Eastern Hill University (NEHU), Shillong,
India. The book presents original research results, new ideas and
practical development experiences which concentrate on both theory
and practices. It includes papers from all areas of information
technology, computer science, electronics and communication
engineering written by researchers, scientists, engineers and
scholar students and experts from India and abroad.
The volume contains latest research work presented at International
Conference on Computing and Communication Systems (I3CS 2016) held
at North Eastern Hill University (NEHU), Shillong, India. The book
presents original research results, new ideas and practical
development experiences which concentrate on both theory and
practices. It includes papers from all areas of information
technology, computer science, electronics and communication
engineering written by researchers, scientists, engineers and
scholar students and experts from India and abroad.
This book entitled "Statistical Analysis of Educational Scenario in
Tripura: A Case Study" is an essential besides reference for all
enthusiasts in the field of educational statistics. The text has
been organized into five chapters. The first chapter is the
introduction of the research problem. It provides a background of
Tripura - a tiny state of north-east India. Data source and review
of literature is also briefly described here. It contains some
mathematical tools and software techniques. Chapter ends with the
contents of the book. The second chapter contains real life data
analysis by pie-diagram. Method of Correspondence Analysis is also
incorporated in third chapter. Whereas chapter four has binary
logistic regression analysis for the same set of real life data by
SPSS. The last chapter i.e., chapter five contain conclusion and
future scope of study. Adequate care has been taken to review the
chapters thoroughly and several interesting observations have been
made through the application of various statistical methods on this
book. It is hoped that this book will open possibilities of new
directions of study.
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