Venous Thromboembolism, a critical area for all pulmonary medicine specialists, is completely reviewed and updated in this issue, which starts with an epidemiological overview and then provides an in-depth look at the following topics: use of clinical probability algorithms (Geneva Score, Wells Criteria, and others), imaging techniques, deep vein thrombosis prophylaxis, chronic thromboembolic pulmonary hypertension, inherted hypercoaguable states, venous thromboembolism and pregnancy, interventional therapies (such as fragmentation, IVC filters, and surgical embolectomy), massive pumonary embolism and the role of thrombolysis, and upper extremity DVT.