The use of drugs as remedies for various types of diseases has a long tradition; however, it has only been recently recognized that the value of any given compound must be evaluated in light of its benefit to risk ratio. When prescribing drugs, physicians must look at the big picture of the drug's benefits in relation to its side effects and possible toxicity. The aim of this handbook is to compile data from various authors, providing clinicians with data that will optimize their decision making in selecting effective, low-risk drug treatments. It also provides research workers, including physicians, pharmacists, and basic scientists, with a sound basis for increasing knowledge of the risk/benefit ratios of various drugs. Includes detailed assessments of the following types of drugs: Antihypertensive agents Diuretics Anti-diabetic drugs Anticonvulsant drugs Drugs for Parkinson's disease Antihistamines and antiserotonins Cytokines and immunomodulators Non-opioid analgesics and anti-inflammatory agents Antibacterial agents Antiviral agents Drugs used in reproductive endocrinology Systemic drugs for skin diseases Topical liposome drugs Topical glucocorticoids

The use of drugs as remedies for various types of diseases has a long tradition; however, it has only been recently recognized that the value of any given compound must be evaluated in light of its benefit to risk ratio. When prescribing drugs, physicians must look at the big picture of the drug's benefits in relation to its side effects and possible toxicity. The aim of this handbook is to compile data from various authors, providing clinicians with data that will optimize their decision making in selecting effective, low-risk drug treatments. It also provides research workers, including physicians, pharmacists, and basic scientists, with a sound basis for increasing knowledge of the risk/benefit ratios of various drugs. Includes detailed assessments of the following types of drugs: oAntihypertensive agents oDiuretics oAnti-diabetic drugs oAnticonvulsant drugs oDrugs for Parkinson's disease oAntihistamines and antiserotonins oCytokines and immunomodulators oNon-opioid analgesics and anti-inflammatory agents oAntibacterial agents oAntiviral agents oDrugs used in reproductive endocrinology oSystemic drugs for skin diseases oTopical liposome drugs oTopical glucocorticoids

Over the last 35 years, synthetic detergents have become increasingly important as skin cleansing agents. With the vast range of soaps and synthetic cleansers available nowadays, doctors and pharmacists are expectedto advise on how to cleanse normal as well as diseased skins. Sound advice must include knowledge of the nature, composition, and action of the available surfactants and cleanser preparations, the physiology and pathophysiology of the skin surface, the microbial ecology ofthe skin, and the factors that control the skin flora. Much of this knowledge is the result of recent research. Health care professionals must be familiar, not only with the benefits, but also with the possible adverse effects of synthetic detergents on the human skin (roughness, water loss, etc.) and on the environment. This monograph draws upon the expertise of numerous scientists to present a comprehensive view of the subject.

In a multi-disciplinary approach the book deals with liposome dermatics fromthe chemist's, pharmacist's, biologist's as well as clinician's point of view. It features the production of liposomes, appropriate raw materials, encapsulation of active ingredients, possible incorporation into vehicles such as gels, assessment of stability, fate of liposomes and active ingredients exposed to animaland human skin both in vitro and in vivo, activity of topical liposome preparations in normal and inflamed skin in animal and man as well as efficacy in skin diseases in man. Other aspects covered comprise the ecological and juridic area. The scope being theoretical and practical at a time, the book provides a sound basis for future developments to meet the needs of patients suffering from so far recalcitrant skin diseases.

Bei der Behandlung von Hauterkrankungen spielt die oertliche Anwendung von Arzneimitteln eine zentrale Rolle; alternativ kommt aber auch immer haufiger eine innerliche oder systemische Therapie in Betracht. In vielen Fallen gilt es, topische und systemische Therapie miteinander in sinnvoller Weise zu verbinden. Dieses Buch berucksichtigt beide Therapieformen in adaquater Weise und erweist sich aufgrund seiner knappen, pragnanten Darstellung als sehr praxisorientiert. Auch der Allgemeinmediziner, der zunehmend mit dermatologischen Fragestellungen konfrontiert wird, findet in diesem Buch kompaktes Wissen fur die Praxis. Fur Dermatologen, Internisten, Gynakologen, HNO-AErzte, Apotheker

Hautreinigungsmittel sind in zunehmendem Ma e in vielf{lti- ger Form verf}gbar, und der Arzt ist auf sie bei verschiede- nen Therapien angewiesen. Im vorliegenden Band werden alle Wirkungen und Nebenwirkungen abgehandelt.

Das vorliegende Buch enthAlt eine aktuelle Aoebersicht A1/4ber sexuell A1/4bertragbare Erkrankungen (Sexually Transmitted Diseases, STD) und dient vor allem den Belangen der Arztlichen Praxis sowie aller damit befaAten Sparten der Medizin (z.B. Allgemeinmediziner, Dermato-Venerologen, GynAkologen, Urologen, FachArzte fA1/4r Innere Medizin und Kinderheilkunde). Die Darstellung erlaubt in KA1/4rze einen Aoeberblick A1/4ber die A"tiologie, Pathogenese, Diagnostik und Therapie der einschlAgigen Erkrankungen, wobei besonderer Wert auf heutige wichtige Krankheitsbilder, wie z.B. Chlamydien-Infektionen und AIDS, gelegt wurde. FA1/4r den weiter interessierten Leser stehen Literaturangaben zur ausfA1/4hrlichen Information zur VerfA1/4gung.