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This book introduces fundamental principles and practical
application of techniques used in the scalable production of
biopharmaceuticals with animal cell cultures. A broad spectrum of
subjects relevant to biologics production and manufacturing are
reviewed, including the generation of robust cell lines, a survey
of functional genomics for a better understanding of cell lines and
processes, as well as advances in regulatory compliant upstream and
downstream development. The book is an essential reference for all
those interested in translational animal cell-based pharmaceutical
biotechnology.
Tissue Engineering, Second Edition, provides a comprehensive volume
that integrates a wide spectrum of methods required to implement
current and future progress in tissue engineering. Leading experts
in various disciplines provide examples of recent advances in
tissue engineering-related methodologies. Authors present
authoritative discussions on topics including in vitro expansion of
tissue cells by conditional proliferation; stem cell engineering
using transducible Cre recombinase; skeletal stem cells for tissue
engineering; synthetic hydrogel matrices for guided bladder tissue
regeneration; artificial skin; artificial pancreas; cardiomyocytes
from human and mouse embryonic stem cells; and biological scaffolds
for heart valve tissue engineering. Tissue Engineering, Second
Edition, supplies an understanding of diverse technologies and
methods used to drive tissue engineering into a clinical reality.
The knowledge contained in this volume represents the impressive
progress made in the decade that tissue engineering has rapidly
evolved.
"Hauser and Wagner have presented the new possibilities of
Mammalian Cell Biology in a very informative and stimulating
manner." Prof. Dr. Hans Fritz, Ludwig-Maximilians-University Munich
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