Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

The latest in the series of literature reviews designed to keep specialists in genetics and related fields abreast of current developments. The five articles cover the lethal osteochondrodysplasias, mutations in type I procollagen genes that cause osteogenesis imperfecta, structural defects in inher

The series comprises critical review articles that keep researchers in different areas of the field informed on the latest research results, ideas, and advances. Contributions to Volume 21 focus on: the clinically diverse diseases classified as peroxisomal disorders; X-linked immunodeficiencies; gen

This book discusses how consultations with young children could signal a change of thinking about how children might influence policy and shape the development of a child-friendly state. While the consultations in this study were germane to political decisions, they took place as multi-modal dialogue with children in their educational settings. Framed by Australia's national early years learning framework which focuses on children's belonging and identity, the consultations saw unique partnerships formed among children, educators, families and policy officers, providing ways in which children's voices may be engaged in educational spaces throughout the world. Using a qualitative case study approach, these consultations were documented through observations, interviews, artefact collection and document analyses, allowing the authors to construct a framework for engaging children as citizens that is transferable to a variety of settings. Chapters provide: * an insight into the various aspects involved in children's consultations from conceptualizing and planning consultations with young children, to implementation and documentation, through to the uptake and consequence of children's messages; * factors that contribute to the effectiveness of consultations, challenges that arise, and areas for improvement when engaging with children's voices; * implications for children's participation as valued citizens and a framework for considering young children's voices in decision-making processes. This book offers fresh ideas for working with young children in the decision making process and will appeal to early childhood researchers, educators, policymakers and practitioners across various sectors, agencies and disciplines.

Structural Modeling and Experimental Techniques presents a current treatment of structural modeling for applications in design, research, education, and product development. Providing numerous case studies throughout, the book emphasizes modeling the behavior of reinforced and prestressed concrete and masonry structures.

Structural Modeling and Experimental Techniques:

o Concentrates on the modeling of the true inelastic behavior of structures
o Provides case histories detailing applications of the modeling techniques to real structures
o Discusses the historical background of model analysis and similitude principles governing the design, testing, and interpretation of models
o Evaluates the limitations and benefits of elastic models
o Analyzes materials for reinforced concrete masonry and steel models
o Assesses the critical nature of scale effects of model testing
o Describes selected laboratory techniques and loading methods
o Contains material on errors as well as the accuracy and reliability of physical modeling
o Examines dynamic similitude and modeling techniques for studying dynamic loading of structures
o Covers actual applications of structural modeling

This book serves students in model analysis and experimental methods, professionals manufacturing and testing structural models, as well as professionals testing large or full-scale structures - since the instrumentation techniques and overall approaches for testing large structures are very similar to those used in small-scale modeling work.

With his unique and powerful voice, Tony Hadley has been a successful music artist for more than forty years, from fronting one of the biggest bands of the 80s, Spandau Ballet, to now enjoying a thriving solo career around the world. Featuring stunning imagery and behind-the-scenes photos from his musical adventures, this beautifully illustrated book also captures other professional highlights, like starring on stage in Chicago and appearing on I'm a Celebrity... Get Me Out of Here!, as well as his charity work, celebrity friends, childhood in north London and special family moments. With snaps from his personal photo albums, this amazing visual journey is accompanied by Tony's heartfelt and insightful anecdotes.

From reviews of previous volumes in the series: 'Extremely valuable...thoroughly recommended.'-Annals of Human Genetics 'The most lucid and stimulating discussions of the topic to be found anywhere.'-American Scientist

The current volume includes chapters on peroxisomal disorders, genetic aspects of cancer, Gaucher disease, and other topics.

During the last few years the science of human genetics has been expanding almost explosively. Original papers dealing with different aspects of the subject are appearing at an increasingly rapid rate in a very wide range of journals, and it becomes more and more difficult for the geneticist and virtually impossible for the non geneticist to keep track of the develop ments. Furthermore, new observations and discoveries relevant to an overall understanding of the subject result from investigations using very diverse techniques and methodologies and originating in a variety of different disciplines. Thus, investigations in such various fields as enzymology, immunology, protein chemistry, cytology, pediatrics, neurology, internal medicine, anthropology, and mathematical and statistical genetics, to name but a few, have each contributed results and ideas of general significance to the study of human genetics. Not surprisingly it is often difficult for workers in one branch of the subject to assess and assimilate findings made in another. This can be a serious limiting factor on the rate of progress. Thus, there appears to be a real need for critical review articles which summarize the positions reached in different areas, and it is hoped that "Advances in Human Genetics" will help to meet this requirement. Each of the contributors has been asked to write an account of the position that has been reached in the investigations of a specific topic in one of the branches of human genetics."

From reviews of previous volumes in the series: 'Extremely valuable...thoroughly recommended.'-Annals of Human Genetics 'The most lucid and stimulating discussions of the topic to be found anywhere.'-American Scientist

Sir Alex Ferguson said that his brief as Manchester United manager was to "knock Liverpool off their f*****g perch". After over 2,000 games and 25 seasons, this year he finally succeeded. Following an endless supply of trophies, none meant more to United's global legion of fans than their 19th league title - simply because it finally put Liverpool in their place. It has taken Sir Alex 25 years to establish United as the leader of the championship pack. When Alan Hansen captained Liverpool to their most recent championship in 1990, the tally read 18-7 in Liverpool's favour and few would have given the Scot a prayer of capturing one championship, never mind 12. In "19", award-winning journalist Harry Harris looks back at all the title winning seasons and analyses each one from the viewpoint of a player who distinguished himself in that title year, building up to the record title and an in-depth analysis of the 2010-11 season and how United finally surpassed Liverpool. The book looks at the record through the eyes of those who took part in each of them, or who observed them from close quarters. "19" features exclusive interviews with Arthur Albiston, Alan Brazil, Steve Bruce, Garth Crooks, Gary Pallister, Paul Parker, Lee Sharpe, Gordon Taylor, Dave Whelan, Ray Wilkins.