This book presents a major research program investigating signal transduction processes utilizing small molecule compound probes. The program was launched by the National Natural Science Foundation of China during the 11th Five-Year Plan period, which was started in October 2008 and concluded at the end of 2016. It first summarizes the overall scientific objectives and the current situation of signal transduction research in China and the international frontier. Based on the new method and technologies achieved in small molecule compound probes, this book illustrates key molecular events in signal transduction processes in living systems and reveals the regulation of signal transduction. This helps to explore new ideas and strategies for the diagnosis and prevention of serious diseases. In addition, via interdisciplinary cooperation of biology and chemistry, this book solves some key scientific problems in biology and promotes recent developments in these fields. These areas include the generation of small molecule compound probes for studying signal transduction and development of detecting methods for gathering information of biomacromolecule activities. Given its scope, the book is of interest to researchers who work in organic chemistry, natural product chemistry, medicinal chemistry, analytical chemistry and physical chemistry. It also promotes the multidisciplinary collaboration among chemistry, medicine, materials science and biology

This book provides systematic descriptions of design methods, typical techniques, and validation methods for lunar soft landers, covering their environmental design, system design, sub-system design, assembly, testing and ground test validation based on the Chang'e-3 mission. Offering readers a comprehensive, systematic and in-depth introduction to the technologies used in China's lunar soft landers, it presents detailed information on the design process for Chang'e-3, including methods and techniques that will be invaluable in future extraterrestrial soft lander design. As such, the book offers a unique reference guide for all researchers and professionals working on deep-space missions around the globe.

This book focuses on the design, development, management, governance and application of evolving software processes that are aligned with changing business objectives, such as expansion to new domains or shifting to global production. In the context of an evolving business world, it examines the complete software process lifecycle, from the initial definition of a product to its systematic improvement. In doing so, it addresses difficult problems, such as how to implement processes in highly regulated domains or where to find a suitable notation system for documenting processes, and provides essential insights and tips to help readers manage process evolutions. And last but not least, it provides a wealth of examples and cases on how to deal with software evolution in practice. Reflecting these topics, the book is divided into three parts. Part 1 focuses on software business transformation and addresses the questions of which process(es) to use and adapt, and how to organize process improvement programs. Subsequently, Part 2 mainly addresses process modeling. Lastly, Part 3 collects concrete approaches, experiences, and recommendations that can help to improve software processes, with a particular focus on specific lifecycle phases. This book is aimed at anyone interested in understanding and optimizing software development tasks at their organization. While the experiences and ideas presented will be useful for both those readers who are unfamiliar with software process improvement and want to get an overview of the different aspects of the topic, and for those who are experts with many years of experience, it particularly targets the needs of researchers and Ph.D. students in the area of software and systems engineering or information systems who study advanced topics concerning the organization and management of (software development) projects and process improvements projects.

This book provides systematic descriptions of design methods, typical techniques, and validation methods for lunar soft landers, covering their environmental design, system design, sub-system design, assembly, testing and ground test validation based on the Chang'e-3 mission. Offering readers a comprehensive, systematic and in-depth introduction to the technologies used in China's lunar soft landers, it presents detailed information on the design process for Chang'e-3, including methods and techniques that will be invaluable in future extraterrestrial soft lander design. As such, the book offers a unique reference guide for all researchers and professionals working on deep-space missions around the globe.

This book focuses on the design, development, management, governance and application of evolving software processes that are aligned with changing business objectives, such as expansion to new domains or shifting to global production. In the context of an evolving business world, it examines the complete software process lifecycle, from the initial definition of a product to its systematic improvement. In doing so, it addresses difficult problems, such as how to implement processes in highly regulated domains or where to find a suitable notation system for documenting processes, and provides essential insights and tips to help readers manage process evolutions. And last but not least, it provides a wealth of examples and cases on how to deal with software evolution in practice. Reflecting these topics, the book is divided into three parts. Part 1 focuses on software business transformation and addresses the questions of which process(es) to use and adapt, and how to organize process improvement programs. Subsequently, Part 2 mainly addresses process modeling. Lastly, Part 3 collects concrete approaches, experiences, and recommendations that can help to improve software processes, with a particular focus on specific lifecycle phases. This book is aimed at anyone interested in understanding and optimizing software development tasks at their organization. While the experiences and ideas presented will be useful for both those readers who are unfamiliar with software process improvement and want to get an overview of the different aspects of the topic, and for those who are experts with many years of experience, it particularly targets the needs of researchers and Ph.D. students in the area of software and systems engineering or information systems who study advanced topics concerning the organization and management of (software development) projects and process improvements projects.

This book constitutes the proceedings of the 7th International Conference on Intelligence Science and Big Data Engineering, IScIDE 2017, held in Dalian, China, in September 2017.The 48 full papers and 14 short papers presented in this volume were carefully reviewed and selected from 121 submissions. They deal with statistics and learning; deep neural networks; faces and people; objects; classification and clustering; imaging; biomedical signal processing; and recommendation.