Plasma membrane-associated channels known as gap junctions, along with their protein building blocks-connexins-have an important functional role in a range of immunological processes, including heart function, cell growth and specialization, and early development. Spanning basic science and potential clinical applications, Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology assembles and synthesizes four decades of the most important research carried out in this field. The book first provides a historical overview of the discovery of these membrane channels in cells and tissues of the immune system. It describes their general molecular and biological characteristics and examines how they participate in the evolution, organization, function, and regulation of leukocytes, as well as their interaction with other tissues. The next section examines immunologically related disease scenarios where gap junctions and connexins have been shown to play a fundamental role. The contributors explain how gap junctional communication participates in the establishment and maintenance of immunological properties such as antibody and cytokine production, as well as lymphocyte immune surveillance in both physiological and pathological conditions. The book explores the most important technical approaches used and how they have been specially adapted to answer key biological questions particular to the mobile nature of leukocytes. It also describes the most recent understanding of how gap junctions and connexins participate in antigen recognition, cross-presentation, lymphocyte activation, and in the assembly and function of the immunological synapse. Finally, the book focuses on the latest progress made on translating the knowledge gained to specific treatment modalities. Topics in this section include approaches for reducing scarring and cardiac arrhythmia, combating inflammation in the central nervous system, and enhancing epithelial tissue repair. A comprehensive view of achievements in this promising field, the book will inform and update specialists, clinical practitioners, and those studying the potential for commercial applications.

Witty, entertaining, and informative, this book on so-called 'false friends' will be of immediate use to anyone using the French language and needing to understand French society and culture. The individual entries have been carefully designed to carry the basic linguistic information required and then develop into a wider consideration of the social and cultural context within which the specific words and phrases are used in current French. As this title is supposed to be used in conjunction with and not instead of a dictionary, it also offers a brief list of recommended reading ranging from standard dictionaries to introductory works on French society and institutions.

Plasma membrane-associated channels known as gap junctions, along with their protein building blocks connexins have an important functional role in a range of immunological processes, including heart function, cell growth and specialization, and early development. Spanning basic science and potential clinical applications, Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology assembles and synthesizes four decades of the most important research carried out in this field.

The book first provides a historical overview of the discovery of these membrane channels in cells and tissues of the immune system. It describes their general molecular and biological characteristics and examines how they participate in the evolution, organization, function, and regulation of leukocytes, as well as their interaction with other tissues.

The next section examines immunologically related disease scenarios where gap junctions and connexins have been shown to play a fundamental role. The contributors explain how gap junctional communication participates in the establishment and maintenance of immunological properties such as antibody and cytokine production, as well as lymphocyte immune surveillance in both physiological and pathological conditions. The book explores the most important technical approaches used and how they have been specially adapted to answer key biological questions particular to the mobile nature of leukocytes. It also describes the most recent understanding of how gap junctions and connexins participate in antigen recognition, cross-presentation, lymphocyte activation, and in the assembly and function of the immunological synapse.

Finally, the book focuses on the latest progress made on translating the knowledge gained to specific treatment modalities. Topics in this section include approaches for reducing scarring and cardiac arrhythmia, combating inflammation in the central nervous system, and enhancing epithelial tissue repair. A comprehensive view of achievements in this promising field, the book will inform and update specialists, clinical practitioners, and those studying the potential for commercial applications.

One of the traditional powerhouses of Welsh first class rugby, Aberavon RFC has a long, proud and illustrious history, with 50 of its players being capped for Wales, the club winning many league titles and domestic cups, and - with Neath RFC - facing the might of South Africa, Australia and New Zealand. Aberavon RFC is a great rugby club and this is its story. Fully illustrated and packed with photos and club memorabilia, The Wizards is a comprehensive history of the town's premier club, from the days when the men of Aberavon gathered on a farmer's field to challenge rivals from across south Wales, to the formation of the Afan Football Club in 1876 and its development into Aberavon RFC, and from the club finding a home at the Talbot Athletic Ground to the anniversary celebrations of the 2016-17 season. Aberavon RFC's fascinating 140-year story - lovingly written by renowned rugby historians Howard Evans and Phil Atkinson - traces the club's fortunes through its good times, its many challenges and, most importantly, through the personalities who've worn the famous black and red jersey, delighting the home supporters and putting fear into visiting teams. From the days of `One-Arm' Wilkins to `Warhorse' Jones, The Wizards recalls the great names such as Johnny Ring, Ned Jenkins, John Bevan, Clive Shell, Ray Giles, Billy Mainwaring, Max Wiltshire, `Om the Bomb', Allan Martin and Billy James, to current heroes `Buddah', Jamie Davies and Richard Morris, with a special place for the club's greatest supporter, the legendary and much missed Mrs Evelyn Mainwaring.

Sir William Randal Cremer (18 March 1828 - 22 July 1908) usually known by his middle name "Randal", was an English Liberal Member of Parliament, a pacifist, and a leading advocate for international arbitration. He was awarded the Nobel Peace Prize in 1903 for his work with the international arbitration movement.

The world of rugby celebrated the 8th Rugby World Cup in 2015, but a tournament held in 1919, The King's Cup, can rightly claim to be rugby's first competitive 'World Cup'. Meticulously complied by Howard Evans and Phil Atkinson, The King's Cup 1919, is the first book to tell the story of rugby's first 'World Cup' and is essential reading for all rugby enthusiasts and military historians. With over 140 photos and illustrations, and chapters focusing on the competing teams, the players, and every game in the tournament, the authors have provided a comprehensive and attractive record of a long-forgotten but historically important competition that most rugby supporters are completely unaware of. At the outbreak of World War I in 1914, all rugby was suspended by decree of the individual rugby unions, with only inter-military encounters and fundraising games permitted. After the Armistice in November 1918, with the armies of the world's rugby-playing nations still stationed in Britain, and with the public desperate to see competitive rugby played again, an inter-military tournament was organised.King George V was so enthused by the proposed competition that he agreed to have the tournament named after him, and so The King's Cup was born. The King's Cup 1919 Explains the British military's refusal to allow separate teams for England, Wales, Scotland or Ireland by the creation of 'Mother Country' Explains how the Royal Navy were invited to compete but declined Confirmed the status of New Zealand as the dominant rugby-playing nation Saw the first competitive game between New Zealand and South Africa Shows the origins of apartheid South Africa's refusal to accept black players in opposing teams

Title: The London Rambler and Footpath Guide to the surrounding districts ... Reprinted (with additions) by permission from the "Echo.'.Publisher: British Library, Historical Print EditionsThe British Library is the national library of the United Kingdom. It is one of the world's largest research libraries holding over 150 million items in all known languages and formats: books, journals, newspapers, sound recordings, patents, maps, stamps, prints and much more. Its collections include around 14 million books, along with substantial additional collections of manuscripts and historical items dating back as far as 300 BC.The HISTORY OF BRITAIN & IRELAND collection includes books from the British Library digitised by Microsoft. As well as historical works, this collection includes geographies, travelogues, and titles covering periods of competition and cooperation among the people of Great Britain and Ireland. Works also explore the countries' relations with France, Germany, the Low Countries, Denmark, and Scandinavia. ++++The below data was compiled from various identification fields in the bibliographic record of this title. This data is provided as an additional tool in helping to insure edition identification: ++++ British Library Evans, Howard; 1884. 89 p.; 8 . 10350.bbb.28.

This scarce antiquarian book is a selection from Kessinger Publishing's Legacy Reprint Series. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment to protecting, preserving, and promoting the world's literature. Kessinger Publishing is the place to find hundreds of thousands of rare and hard-to-find books with something of interest for everyone!

This scarce antiquarian book is a selection from Kessinger Publishing's Legacy Reprint Series. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment to protecting, preserving, and promoting the world's literature. Kessinger Publishing is the place to find hundreds of thousands of rare and hard-to-find books with something of interest for everyone!

Title: From Serfdom to Manhood: a story of Agricultural life. ... Reprinted from the Labourer's Union Chronicle.Publisher: British Library, Historical Print EditionsThe British Library is the national library of the United Kingdom. It is one of the world's largest research libraries holding over 150 million items in all known languages and formats: books, journals, newspapers, sound recordings, patents, maps, stamps, prints and much more. Its collections include around 14 million books, along with substantial additional collections of manuscripts and historical items dating back as far as 300 BC.The GENERAL HISTORICAL collection includes books from the British Library digitised by Microsoft. This varied collection includes material that gives readers a 19th century view of the world. Topics include health, education, economics, agriculture, environment, technology, culture, politics, labour and industry, mining, penal policy, and social order. ++++The below data was compiled from various identification fields in the bibliographic record of this title. This data is provided as an additional tool in helping to insure edition identification: ++++ British Library Evans, Howard; 1875]. 8 . 12638.bbb.5.

During the six years of a brutal global war - from the battlefields of Europe, to the deserts of North Africa, the jungles of the Asia and even in Prisoner of War camps - rugby union continued to be played wherever and whenever possible by the servicemen of Britain and her Allies from New Zealand, Australia and South Africa, Dedicated to 'all those in rugby who did - and who didn't - make it through those troubled times', War Games is a comprehensive and highly illustrated commemoration, packed with stories and statistics that for the first time chronicles the history of rugby - the men and the matches, from `scratch' to international - during the Second World War. Starting with the short-lived 'infant' season of 1939-40 and ending with the `Victory' series of internationals in 1945-6, and including the hugely successful New Zealand Expeditionary Force (NZEF) 'Kiwi' tour of 1946, War Games details all the major rugby contests and the hundreds of players including: Bleddyn Williams, Prince Alex Obolensky, Bill McLaren, Wilf Wooller, Blair Mayne, Sir Tasker Watkins, Ralph Sampson, Gus Risman, Willie Davies, Les Manfield, Charlie Saxton, Fred Allen and Jim Sherratt. Essential and entertaining reading for followers of rugby and military historians alike, respected rugby authors Howard Evans and Phil Atkinson tell the tale - meticulously and with great affection for the game they love - of those men who played for fun but who, on too many occasions, lost more than a rugby game.