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This book explores the latest data dealing with mechanosensitive
channels research results. It was compiled by a group of
internationally recognized scientists leading in the field of
mechanosensitive ion channels or mechanically gated channels and
signaling cascades research. Key problems of cell mechanobiology
are also discussed. As a whole, the volume dwells on the major
issues of mechanical stress influencing the ion channels and
intracellular signaling pathways.
This book presents the latest findings in mechanosensitive ion
channel research compiled by a number of internationally recognized
experts in the field of mechanosensitivity, specializing in
mechanosensitive or mechanically gated ion channels and the
underlying mechanosensitive signaling cascades. The book provides a
comprehensive description of mechanotransduction, which is defined
as the biochemical response of cells to mechanical stimulation, and
provides the reader with the latest vision of signaling cascades.
Descriptions of the most widely used experimental models, the
methods of choice and references to experimental protocols, the
latest experimental findings and current vision, and potential
problems in data interpretation, will be of considerable use to all
those interested in this field of research.
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