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This second edition comes at a time of a paradigm shift in
understanding of the molecular pathology and neuroscience of brain
and spinal tumors of childhood and their mechanisms of growth
within the developing brain. Excellent collaborative translational
networks of researchers are starting to drive change in clinical
practise through the need to test many ideas in trials and
scientific initiatives. This text reflects the growing concern to
understand the impact of the tumour and its treatment upon the full
functioning of the child's developing brain and to integrate the
judgments of the risks of acquiring brain damage with the risk of
death and the consequences for the quality of life for those who
survive. Information on the principles of treatment has been
thoroughly updated. A chapter also records the extraordinary work
done by advocates. All medical and allied professionals involved in
any aspect of the clinical care of these patients will find this
book an invaluable resource.
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