The inducible isoforms of the enzymes cyclooxygenase (COX 2), nitric oxide synthase (iNOS) and heme oxygenase 1 (HO-1) have generated great interest as possible therapeutic targets in inflammation. This book is the first publication to address the importance of all three enzymes and the consequences of their interactions to the inflammatory process. The book brings together overviews by leading researchers in the field of the current status of knowledge of COX, NOS and HO in inflammation. These overviews cover a series of new concepts in the mechanism of inflammation. Topics include inducible enzyme involvement in inflammatory processes including the role in vascular permeability, leukocycte migration, granuloma formation, angiogenesis, neuroinflammation and algesia. New findings from transgenic animal models are reviewed. Other chapters address the importance of these enzymes in inflammatory disease states including rheumatoid arthritis, atherosclerosis and multiple sclerosis. The possibility of selective inhibitors or inducers of COX, NOS and HO, and their use in the clinic is discussed. The subject matter of this book is of interest to rheumatologists, pathologists, pharmacologists, neuroscientists and anyone with an academic interest in the mechanisms of inflammation.

Basic income is an innovative, powerful egalitarian response to widening global inequalities and poverty experiences in society, one that runs counter to the neoliberal transformations of modern welfare states, social security, and labor market programs. This book is the first collective volume of its kind to ask whether a basic income offers a viable solution to the income support systems in Australia and New Zealand. Though often neglected in discussions of basic income, both countries are advanced liberal democracies dominated by neoliberal transformations of the welfare state, and therefore have great potential to advance debates on the topic. The contributors' essays and case studies explore the historical basis on which a basic income program might stand in these two countries, the ideological nuances and complexities of implementing such a policy, and ideas for future development that might allow the program to be put into practice regionally and applied internationally.

Basic income is an innovative, powerful egalitarian response to widening global inequalities and poverty experiences in society, one that runs counter to the neoliberal transformations of modern welfare states, social security, and labor market programs. This book is the first collective volume of its kind to ask whether a basic income offers a viable solution to the income support systems in Australia and New Zealand. Though often neglected in discussions of basic income, both countries are advanced liberal democracies dominated by neoliberal transformations of the welfare state, and therefore have great potential to advance debates on the topic. The contributors' essays and case studies explore the historical basis on which a basic income program might stand in these two countries, the ideological nuances and complexities of implementing such a policy, and ideas for future development that might allow the program to be put into practice regionally and applied internationally.

It is now routine to offer men the opportunity to bank sperm prior to medical treatments where there is a high risk of testicular damage. Some men also elect to bank sperm prior to vasectomy or before embarking on a high-risk activity, such as joining the armed services. This book examines the processes involved in banking sperm from sample production and storage, the subsequent treatment of the patient and the maintenance of the samples in storage, to the process of follow-up and the ultimate fate of frozen samples. Sperm Banking: Theory and Practice will be of particular interest to andrologists and embryologists involved in the running and establishment of sperm-banking services. The book will also be useful to medical and nursing professionals and counsellors involved in the diagnosis and treatment of conditions where there is a risk of infertility as a consequence of the treatment, including oncologists, hematologists and urologists.

Photo's by Pam is a small collection of photo's Pamela J Tomlinson took from her home or around her town North East, Maryland in Cecil County, Maryland