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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Inducible Enzyme in the Inflammatory Response (Hardcover)
Loot Price: R2,600
Discovery Miles 26 000
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Inducible Enzyme in the Inflammatory Response (Hardcover)
Series: Progress in Inflammation Research
Expected to ship within 12 - 19 working days
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The inducible isoforms of the enzymes cyclooxygenase (COX 2),
nitric oxide synthase (iNOS) and heme oxygenase 1 (HO-1) have
generated great interest as possible therapeutic targets in
inflammation. This book is the first publication to address the
importance of all three enzymes and the consequences of their
interactions to the inflammatory process. The book brings together
overviews by leading researchers in the field of the current status
of knowledge of COX, NOS and HO in inflammation. These overviews
cover a series of new concepts in the mechanism of inflammation.
Topics include inducible enzyme involvement in inflammatory
processes including the role in vascular permeability, leukocycte
migration, granuloma formation, angiogenesis, neuroinflammation and
algesia. New findings from transgenic animal models are reviewed.
Other chapters address the importance of these enzymes in
inflammatory disease states including rheumatoid arthritis,
atherosclerosis and multiple sclerosis. The possibility of
selective inhibitors or inducers of COX, NOS and HO, and their use
in the clinic is discussed. The subject matter of this book is of
interest to rheumatologists, pathologists, pharmacologists,
neuroscientists and anyone with an academic interest in the
mechanisms of inflammation.
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