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A central concept in the evolutionary theory of senescence is the
idea that ageing results from life-history trade-offs. In
particular, the disposable soma theory suggests that longevity is
determined through the setting of longevity assurance mechanisms so
as to provide an optimal compromise between investments in somatic
maintenance (including stress resistance) and in reproduction.
Comparative studies among mammalian species confirm that cells from
long-lived species appear to have a greater intrinsic capacity to
withstand stresses than cells from short-lived species.
Childbearing at older ages has become increasingly common in modern
societies because of demographic changes, medical progress and
personal choice. While the detrimental effects of late reproduction
on infant mortality and genetic diseases have been well documented,
little is known about the possible postponed detrimental effects of
late parenting.
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