Since its original publication in Paris in 1959, Naked Lunch has become one of the most important novels of the twentieth century. Exerting its influence on the relationship of art and obscenity, it is one of the books that redefined not just literature but American culture. For the Burroughs enthusiast and the neophyte, this volume--that contains final-draft typescripts, numerous unpublished contemporaneous writings by Burroughs, his own later introductions to the book, and his essay on psychoactive drugs--is a valuable and fresh experience of a novel that has lost none of its relevance or satirical bite.

Lees draws on Burroughs' search for an addiction cure to discover a ground-breaking treatment for shaking palsy, and learns how to use the deductive reasoning of Sherlock Holmes to diagnose patients. Lees follows Burroughs into the rainforest and under the influence of yage (ayahuasca) gains insights that encourage him to pursue new lines of pharmacological research and explore new forms of science.

First Naked Lunch, Burroughs's original manuscript entitled Interzone includes a long and brilliant section known as "WORD". This previously unpublished text is the highlight of Interzone.