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The purpose of this easy-to-use handbook is to provide a quick,
accessible reference to nucleobase complexes. It describes these
complexes with reference to methods of preparation, their
characterization, and their toxicity and therapeutic indices. It
lists the modes of coordination together with the relevant spectral
data and major methods of investigation. This concise resource
guide also includes data on the uncomplexed bases, such as
solubility, pk, accepted structures in the solid state and
solutions, and the natural occurrence of the base. Investigators in
the fields of transition metal chemistry, biological inorganic
chemistry and those working in medical laboratories will find this
handbook indispensable.
This handbook describes methods of preparation, characterization,
toxicity, and therapeutic indices of transition metal complexes of
the naturally occurring heterocyclic nucleobases and their
derivatives. Modes of coordination are listed together with the
relevant spectral data and major methods of investigation. Where
appropriate, the spectrum of the sample is included in the
pertinent section on spectroscopy. Data on the uncomplexed bases,
such as solubility, pK, accepted structure(s) in the solid state
and solutions, and the natural occurrence of the base are also
included. Volume II of this work provides the spectroscopic data to
accompany Volume I. Volume II is divided into two sections: Section
1 summarizes the data and Section 2 is comprised of figures. In
Section 1, the complexes are arranged according to the method of
study. In Section 2, figures are listed by base type and follow the
sequence of Volume I, mainly complexes of the pyrimidine bases,
nucleosides and nucleotides, and then purine bases, nucleosides,
and nucleotides.
This handbook describes methods of preparation, characterization,
toxicity, and therapeutic indices of transition metal complexes of
the naturally occurring heterocyclic nucleobases and their
derivatives. Modes of coordination are listed together with the
relevant spectral data and major methods of investigation. Where
appropriate, the spectrum of the sample is included in the
pertinent section on spectroscopy. Data on the uncomplexed bases,
such as solubility, pK, accepted structure(s) in the solid state
and solutions, and the natural occurrence of the base are also
included. Volume II of this work provides the spectroscopic data to
accompany Volume I. Volume II is divided into two sections: Section
1 summarizes the data and Section 2 is comprised of figures. In
Section 1, the complexes are arranged according to the method of
study. In Section 2, figures are listed by base type and follow the
sequence of Volume I, mainly complexes of the pyrimidine bases,
nucleosides and nucleotides, and then purine bases, nucleosides,
and nucleotides.
The purpose of this easy-to-use handbook is to provide a quick,
accessible reference to nucleobase complexes. It describes these
complexes with reference to methods of preparation, their
characterization, and their toxicity and therapeutic indices. It
lists the modes of coordination together with the relevant spectral
data and major methods of investigation. This concise resource
guide also includes data on the uncomplexed bases, such as
solubility, pk, accepted structures in the solid state and
solutions, and the natural occurrence of the base. Investigators in
the fields of transition metal chemistry, biological inorganic
chemistry and those working in medical laboratories will find this
handbook indispensable.
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