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Part of the in-depth and practical Pattern Recognition series,
Practical Surgical Soft Tissue Pathology, 2nd Edition, helps you
arrive at an accurate diagnosis by using a proven pattern-based
approach. Leading diagnosticians guide you through the most common
patterns seen in soft tissue pathology, applying appropriate
immunohistochemistry and molecular testing, avoiding pitfalls, and
making the best diagnosis. High-quality illustrations capture key
morphologic patterns for a full range of common and rare tumor
types, and a "visual index" at the beginning of the book directs
you to the exact location of in-depth diagnostic guidance. A
consistent chapter organization by histologic pattern considers
soft tissue tumors the way you approach them in daily practice,
helping you arrive at a quick and accurate diagnosis. A
user-friendly design color-codes patterns to specific entities, and
key points are summarized in tables and text boxes, so you can
quickly and easily find what you are looking for. Sweeping content
updates keep you at the forefront of recent findings regarding all
major neoplastic and non-neoplastic diseases of the soft tissues.
Improved pattern call-outs are now linked directly within the
chapter, reinforcing the patterns for more efficient and complete
understanding. Expert ConsultT eBook version included with
purchase. This enhanced eBook experience allows you to search all
of the text, figures, and references from the book on a variety of
devices.
Since the publication of the previous edition of Tumors of the
Esophagus and Stomach, great advances in many areas of tumor
biology have led to a better understanding of the pathogenesis,
pathology, and molecular biology of epithelial and stromal
malignancies of the upper gastrointestinal tract. Many of these
advances have led to specific improvements in diagnosis, prognosis,
treatment, and thus, survival in patients affected by these tumors.
This edition of the Fascicle was written to highlight these
advances, and more specifically, to help pathologists diagnose
diseases more accurately and understand how pathology contributes
to clinical treatment in the new age of personalized and targeted
therapy. Notable advances described in this publication include: 1)
expansion of our understanding of the pathologic features and
molecular pathogenesis of carcinomas of the esophagus and stomach,
most of which develop through a chronic
inflammation-metaplasia-dysplasia-carcinoma sequence. Important
refinements in the classification of neoplastic precursor lesions
have been made since the last AFIP series, including the
morphologic and endoscopic subtypes, and this has led to
improvements in surgical treatment with a strong trend toward
minimization in the form of endoscopic mucosal and submucosal
dissections 2) discovery of new diseases, such as gastric
adenocarcinoma and proximal polyposis syndrome (GAPPS), a special
variant of familial adenomatous polyposis, and significant advances
in our knowledge regarding the molecular characterization of
genetic polyposis syndromes 3) great expansion in the
molecular-pathology correlation, morphologic diversity,
classification, and therapeutic options of gastrointestinal stromal
tumors (GISTs) 4) reclassification and refinement of prognostic
factors related to neuroendocrine tumors 5) improvements in the
role of cytology in the diagnosis of tumors of the upper
gastrointestinal tract. This book has been written with the
pathologist in mind first by using tables that illustrate salient
pathologic, molecular, and differential diagnostic features of key
entities that are often difficult to distinguish from each other.
Specific color photographs of classic tumors and morphologic
variants often difficult to recognize are used throughout.
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