We have known for over a thousand years that the brain underlies behavioral expression, but effective scientific study of the brain is only very recent. Two things converge in this book: a great respect for neuroscience and its many variations, and a sense of investigation and inquiry demythologized. Think of it as foraging for coherence.

Naturalism and Pragmatism offers reflections on the pragmatic tradition from a fresh perspective: that of a working neuroscientist. Though naturalism and evolution are not the only topics of discussions, they are important themes of the book. Both pragmatism and modern behavioral science grew up in the wake of Darwin's theory of evolution. Indeed it is impossible to imagine either without evolutionary theory and the more general nineteenth-century trend of naturalism from which modern evolutionary theory emerged. And yet, for a variety of reasons, these common origins have not ensured a close affinity between pragmatic philosophy and the behavioral sciences. Among the wide diversity of scientific theories of human cognition and its evolutionary origins, only a few are congenial to pragmatism in its original or classical' form, which embraces the full range of human experience

Since 2005 a dozen states and more than 15 specialties have reported a physician shortage or anticipate one in the next few years. This anticipated shortage and a worsening of physician distribution are compounded by a projected increased demand for women's healthcare services.

Women's healthcare is particularly vulnerable, because the obstetrician-gynecologist workforce is aging and is among the least satisfied medical specialists. Furthermore, fellowship training in women's healthcare in internal medicine and in maternal child health in family and community medicine involves only a small portion of general internists and family physicians.

In response to this challenge, the Association of American Medical Colleges called for an expansion of medical schools and graduate medical education enrollments. As we cope with significant and rapid changes in organizations and reimbursement, academic departments of obstetrics and gynecology, family and community medicine, and internal medicine have opportunities to create a unified women's health curriculum for undergraduate students, share preventive health and well-woman expertise in training programs, provide improved continuity of care, instill concepts of lifelong learning to our graduates, and better develop our research programs.

This volume's chapters focus on strategic planning on behalf of academic faculty who will train the anticipated additional load of students, residents, and fellows in women's healthcare.
-changing demographics of faculty
-expanding roles of clinician educators
-physician investigators and their future
-the hidden value of part-time faculty
-faculty salaries
-required skillsets of academic leaders
-the meaning of tenure and faculty satisfaction and retention.

Recommendations presented here from authors with distinguished leadership skills indicate a consensus, but not unanimity. In furthering these goals, we summarize in the final chapter our collective expertise and offer ways to implement recommendations to better prepare for tomorrow's needs in academic women's healthcare.

In "Effort: A Behavioral Neuroscience Perspective on the Will," author Jay Schulkin presents a two-fold thesis: there is no absolute separation of the cognitive and non-cognitive brain, and there are diverse cognitive systems, many of which are embodied in motor systems that underlie self-regulation. Central to this thesis is that dopamine is the one neurotransmitter that underlies the diverse senses of effort, and is apparent in most everyday activity, whether solving a problem in our head or moving about.
As scientific literature abounds with studies of decision-making and effort, this book emphasizes the importance of demythologizing our understanding of cognitive systems in order to link motivation, behavioral inhibition, self-regulation, and will.
"Effort" will benefit researchers and students in neuroscience, behavioral neuroscience, cognitive psychology, clinical psychology, social psychology, as well as anyone with interest in this topic.

By integrating sociological, psychological, and biological perspectives, this book aims to demystify and destigmatize a challenging and taboo topic – suicide. It weaves current theories and statistics on suicide into a larger message of how suicide can affect almost anyone, and how urgent prevention needs are. Written in an accessible manner, it assumes no pre-existing knowledge of suicide. The broad nontechnical overview will appeal to general readers and a wide range of disciplines, including politics and policy, biology, psychology, sociology, and psychiatry. It concludes on a positive note, focused on recovery, resilience, and hope. It considers not only how these factors may play a role in suicide prevention, but how, despite persistent suicide rates, we can proceed optimistically and take concrete action to support loved ones or promote suicide prevention efforts.

Preoperative Events switches the focus from post-operative rehabilitation to preoperative experiences and personal histories to lessen the consequences of brain damage. These papers document the relationship between preoperative experience and postoperative performance and discuss a variety of protective preoperative experiences that can ameliorate the deleterious effects of brain damage.

By integrating sociological, psychological, and biological perspectives, this book aims to demystify and destigmatize a challenging and taboo topic – suicide. It weaves current theories and statistics on suicide into a larger message of how suicide can affect almost anyone, and how urgent prevention needs are. Written in an accessible manner, it assumes no pre-existing knowledge of suicide. The broad nontechnical overview will appeal to general readers and a wide range of disciplines, including politics and policy, biology, psychology, sociology, and psychiatry. It concludes on a positive note, focused on recovery, resilience, and hope. It considers not only how these factors may play a role in suicide prevention, but how, despite persistent suicide rates, we can proceed optimistically and take concrete action to support loved ones or promote suicide prevention efforts.

Information molecules, such as Cortico-Releasing Factor (CRF), are ancient and widely distributed across diverse organs, playing various regulatory roles. CRF has been associated with a range of human conditions, including fear and anxiety, social contact, and most recently, addiction - in particular the euphoric feelings associated with alcohol consumption. Since its original discovery, research has unearthed that the role of this molecule is much broader than first thought. The scientific community now knows that CRF is a dynamic and diversely widespread peptide hormone that plays many roles and has many functions, in addition to its role as a releasing factor in the brain. This book explores the role of CRF, examining the relationship between location and function. It considers recurrent features that are linked to CRF - movement and change. CRF expression in regions of the brain is tied to paying attention to novel events and invoking movement in response to those events. Indeed, CRF provokes simple organized rhythmic behavior and can be mobilized under diverse conditions, including adversity. Examining the evolutionary origins of CRH, its neural functions, and its role in a variety of human characteristics and social behaviors, this book provides unique insights into CRF, and will be of interest to students and researchers in Neuroscience, Psychology, and Biology.

The brain is a cognitive organ, and regions of the brain that traverse brainstem and cortical sites orchestrate the expression of bodily sensibility: intelligent action. They can appear perfunctory or intimate, calculating a sum or selecting a mate. Schulkin presents neuroscientific research demonstrating that thought is not on one side and bodily sensibility on the other; from a biological point of view, they are integrated. Schulkin further argues that this integration has important implications for judgements about the emotions, art and music, moral sensibilities, attraction and revulsion, and our perpetual inclination to explain ourselves and our surroundings. He begins the book by setting forth a view of the emotions not as a bodily burden to be borne, but rather as a great source of information. He then moves on to other domains, claiming that underlying the experience of aesthetics in at least some instances is the interplay between expectation and disappointment from its infraction, and suggesting that, among other things, repulsion and attraction to the cries and joys of others consitutes moral responsiveness. This book should appeal to researchers in behavioral neuroscience, emotion, and psychophysiology, as well as cognitive and social psychologists and philosophers of mind.

This book explores the cultures of philosophy and the law as they interact with neuroscience and biology, through the perspective of American jurist Oliver Wendell Holmes' Jr., and the pragmatist tradition of John Dewey. Schulkin proposes that human problem solving and the law are tied to a naturalistic, realistic and an anthropological understanding of the human condition. The situated character of legal reasoning, given its complexity, like reasoning in neuroscience, can be notoriously fallible. Legal and scientific reasoning is to be understood within a broader context in order to emphasize both the continuity and the porous relationship between the two. Some facts of neuroscience fit easily into discussions of human experience and the law. However, it is important not to oversell neuroscience: a meeting of law and neuroscience is unlikely to prove persuasive in the courtroom any time soon. Nevertheless, as knowledge of neuroscience becomes more reliable and more easily accepted by both the larger legislative community and in the wider public, through which neuroscience filters into epistemic and judicial reliability, the two will ultimately find themselves in front of a judge. A pragmatist view of neuroscience will aid and underlie these events.

The decision making process that underlies ovarian hormone therapy (HT) is fallible. Thus, the decision for women to go on HT remains controversial. At a time when confusion still permeates the decision making with regard to HT, this book bridges diverse features that surround the decision making concerning HT. The book is written for both specialists and generalists in the field.

Preoperative Events switches the focus from post-operative rehabilitation to preoperative experiences and personal histories to lessen the consequences of brain damage. These papers document the relationship between preoperative experience and postoperative performance and discuss a variety of protective preoperative experiences that can ameliorate the deleterious effects of brain damage.

This Element introduces a biological approach to cognition, which highlights the significance of allostatic regulation and the navigation of challenges and opportunities. It argues that cognition is best understood as a juggling act, which reflects numerous ongoing attempts to minimize disruptions while prioritizing the sources of information that are necessary to satisfy social and biological needs; and it provides a characterization of the architectural constraints, neurotransmitters, and affective states that shape visual perception, as well as the regulatory capacities that sustain flexible patterns of thought and behavior.

Every day thousands of individuals need to make critical decisions about their health based on numerical information, yet recent surveys have found that over half the population of the United States is unable to complete basic math problems. How does this lack of numerical ability (also referred to as low numeracy, quantitative illiteracy or statistical illiteracy) impact healthcare? What can be done to help people with low numeracy skills? Numerical Reasoning in Judgments and Decision Making about Health addresses these questions by examining and explaining the impact of quantitative illiteracy on healthcare and in specific healthcare contexts, and discussing what can be done to reduce these healthcare disparities. This book will be a useful resource for professionals in many health fields including academics, policy makers, physicians and other healthcare providers.

Cognitive Adaptation: A Pragmatist Perspective argues that there is a fundamental link between cognitive/neural systems and evolution that underlies human activity. One important result is that the line between nature and culture and scientific and humanistic inquiry is quite permeable - the two are fairly continuous with each other. Two concepts figure importantly in our human ascent: agency and animacy. The first is the recognition of another person as having beliefs, desires, and a sense of experience. The second term is the recognition of an object as alive, a piece of biology. Both reflect a predilection in our cognitive architecture that is fundamental to an evolving, but fragile, sense of humanity. The book further argues for a regulative norm of self-corrective inquiry, an appreciation of the hypothetical nature of all knowledge. Schulkin's perspective is rooted in contemporary behavioral and cognitive neuroscience.

Every day thousands of individuals need to make critical decisions about their health based on numerical information, yet recent surveys have found that over half the population of the United States is unable to complete basic math problems. How does this lack of numerical ability (also referred to as low numeracy, quantitative illiteracy or statistical illiteracy) impact healthcare? What can be done to help people with low numeracy skills? Numerical Reasoning in Judgments and Decision Making about Health addresses these questions by examining and explaining the impact of quantitative illiteracy on healthcare and in specific healthcare contexts, and discussing what can be done to reduce these healthcare disparities. This book will be a useful resource for professionals in many health fields including academics, policy makers, physicians and other healthcare providers.

After drawing its first breath, every newborn mammal turns his or her complete attention to obtaining milk. This primal act was once thought to stem from a basic fact: milk provides the initial source of calories and nutrients for all mammalian young. But it turns out that milk is a much more complicated biochemical cocktail and provides benefits beyond nutrition. In this fascinating book, biologists Michael L. Power and Jay Schulkin reveal this liquid's evolutionary history and show how its ingredients have changed over many millions of years to become a potent elixir. Power and Schulkin walk readers through the early origins of the mammary gland and describe the incredible diversification of milk among the various mammalian lineages. After revealing the roots of lactation, the authors describe the substances that naturally occur in milk and discuss their biological functions. They reveal that mothers pass along numerous biochemical signals to their babies through milk. The authors explain how milk boosts an infant's immune system, affects an infant's metabolism and physiology, and helps inoculate and feed the baby's gut microbiome. Throughout the book, the authors weave in stories from studies of other species, explaining how comparative research sheds light on human lactation. The authors then turn their attention to the fascinating topic of cross-species milk consumption-something only practiced by certain humans who evolved an ability to retain lactase synthesis into adulthood. The first book to discuss milk from a comparative and evolutionary perspective, Power and Schulkin's masterpiece reveals the rich biological story of the common thread that connects all mammals.

Cognitive Adaptation: A Pragmatist Perspective argues that there is a fundamental link between cognitive/neural systems and evolution that underlies human activity. One important result is that the line between nature and culture and scientific and humanistic inquiry is quite permeable - the two are fairly continuous with each other. Two concepts figure importantly in our human ascent: agency and animacy. The first is the recognition of another person as having beliefs, desires, and a sense of experience. The second term is the recognition of an object as alive, a piece of biology. Both reflect a predilection in our cognitive architecture that is fundamental to an evolving, but fragile, sense of humanity. The book further argues for a regulative norm of self-corrective inquiry, an appreciation of the hypothetical nature of all knowledge. Schulkin's perspective is rooted in contemporary behavioral and cognitive neuroscience.

The concept of homeostasis, the maintenance of the internal physiological environment of an organism within tolerable limits, is well established in medicine and physiology. In contrast, allostasis is a relatively new idea of 'viability through change'. With allostatic regulation by cephalic involvement, the body adapts to potentially diverse and dangerous situations through the activation of neural, hormonal, or immunological mechanisms. Allostasis explains how regulatory events maintain organismic viability, or not, in diverse contexts with varying set points of bodily needs and competing motivations. This 2005 book introduces the concept of allostasis and sets it alongside traditional views of homeostasis. It addresses basic regulatory systems and examines the behavior of bodily regulation under duress. The basic concepts of physiological homeostasis are integrated with disorders like depression, stress, anxiety and addiction. It will therefore appeal to graduate students, medical students and researchers working in physiology, epidemiology, endocrinology, neuroendocrinology, neuroscience, and psychology.

Recently, an interest in our understanding of well-being within the context of competition and cooperation has re-emerged within the biological and neural sciences. Given that we are social animals, our well-being is tightly linked to interactions with others. Pro-social behavior establishes and sustains human contact, contributing to well-being. Adaptation and Well-Being is about the evolution and biological importance of social contact. Social sensibility is an essential feature of our central nervous systems, and what have evolved are elaborate behavioral ways in which to sustain and maintain the physiological and endocrine systems that underlie behavioral adaptations. Writing for his fellow academics, and with chapters on evolutionary aspects, chemical messengers and social neuroendocrinology among others, Jay Schulkin explores this fascinating field of behavioral neuroscience.

This volume examines the role of steroids and peptides in the regulation of pregnancy and pregnancy outcome, and their long-term effects including possible influences on adult-onset diseases. During pregnancy the placenta acts as a central regulator and coordinator of maternal and fetal physiology, and the onset of labor, through its production and regulation of steroids and peptides. Perturbations to this regulatory system can result in poor pregnancy outcome, such as preterm birth and low birth weight. These in turn are linked to diseases in later life. Intriguingly, many of these regulatory actions of steroids and peptides also occur in the brain. The induction and suppression of peptides by steroids appears to be key to regulatory function in both brain and placenta. These interweaving strands, linking basic science with obstetrics, are all reviewed in depth here producing a fascinating account of an important area of materno-fetal medicine.

Since 2005 a dozen states and more than 15 specialties have reported a physician shortage or anticipate one in the next few years. This anticipated shortage and a worsening of physician distribution are compounded by a projected increased demand for women's healthcare services.

Women's healthcare is particularly vulnerable, because the obstetrician-gynecologist workforce is aging and is among the least satisfied medical specialists. Furthermore, fellowship training in women's healthcare in internal medicine and in maternal child health in family and community medicine involves only a small portion of general internists and family physicians.

In response to this challenge, the Association of American Medical Colleges called for an expansion of medical schools and graduate medical education enrollments. As we cope with significant and rapid changes in organizations and reimbursement, academic departments of obstetrics and gynecology, family and community medicine, and internal medicine have opportunities to create a unified women's health curriculum for undergraduate students, share preventive health and well-woman expertise in training programs, provide improved continuity of care, instill concepts of lifelong learning to our graduates, and better develop our research programs.

This volume's chapters focus on strategic planning on behalf of academic faculty who will train the anticipated additional load of students, residents, and fellows in women's healthcare.
-changing demographics of faculty
-expanding roles of clinician educators
-physician investigators and their future
-the hidden value of part-time faculty
-faculty salaries
-required skillsets of academic leaders
-the meaning of tenure and faculty satisfaction and retention.

Recommendations presented here from authors with distinguished leadership skills indicate a consensus, but not unanimity. In furthering these goals, we summarize in the final chapter our collective expertise and offer ways to implement recommendations to better prepare for tomorrow's needs in academic women's healthcare.

The decision making process that underlies ovarian hormone therapy (HT) is fallible. Thus, the decision for women to go on HT remains controversial. At a time when confusion still permeates the decision making with regard to HT, this book bridges diverse features that surround the decision making concerning HT. The book is written for both specialists and generalists in the field.

The hunger for sodium has been used as a model system in which to study how the brain produces motivated behaviour. In this account of the field Jay Schulkin draws together information across a range of disciplines and topics, ranging from the ecology of salt ingestion to the sodium molecule and the action of various hormones. The phenomenon of sodium hunger was discovered by Curt Richter, the great American psychobiologist, over 50 years ago. Its study has been of interest for some time: to naturalists, psychologists, endocrinologists, physiologists and neuroscientists. This book offers a systematic account of the behaviour of the sodium hungry animal, the endocrine and physiological mechanisms that act to maintain sodium balance and then act on the brain to promote the search for and the ingestion of salt. Finally, the book provides a description of a neural network that orchestrates the behaviour of salt seeking and salt ingestion. Graduate students and research workers in psychology, physiology and neuroscience will find valuable information in this review.

This volume examines the role of steroids and peptides in the regulation of pregnancy and pregnancy outcome, and their long-term effects including possible influences on adult-onset diseases. During pregnancy the placenta acts as a central regulator and coordinator of maternal and fetal physiology, and the onset of labor, through its production and regulation of steroids and peptides. Perturbations to this regulatory system can result in poor pregnancy outcome, such as preterm birth and low birth weight. These in turn are linked to diseases in later life. Intriguingly, many of these regulatory actions of steroids and peptides also occur in the brain. The induction and suppression of peptides by steroids appears to be key to regulatory function in both brain and placenta. These various interweaving strands, linking basic science with obstetrics, are all reviewed in depth here producing a fascinating account of an important area of materno-fetal medicine.