Biology and Engineering of Stem Cell Niches covers a wide spectrum of research and current knowledge on embryonic and adult stem cell niches, focusing on the understanding of stem cell niche molecules and signaling mechanisms, including cell-cell/cell-matrix interactions. The book comprehensively reviews factors regulating stem cell behavior and the corresponding approaches for understanding the subsequent effect of providing the proper matrix molecules, mechanical cues, and/or chemical cues. It encompasses a variety of tools and techniques for developing biomaterials-based methods to model synthetic stem cell niches in vivo, or to enhance and direct stem cell fate in vitro. A final section of the book discusses stem cell niche bioengineering strategies and current advances in each tissue type.

"Micro- and Nanoengineering of the Cell Surface"explores the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes. The book is accessible for readers across industry, academia, and in clinical settings in multiple disciplines, including materials science, engineering, chemistry, biology, and medicine. Written by leaders in the field, it covers numerous cell surface engineering methods along with their current and potential applications in cell therapy, tissue engineering, biosensing, and diagnosis.

The interface of chemistry, materials science, and biology presents many opportunities for developing innovative tools to diagnose and treat various diseases. However, cell surface engineering using chemistry and materials science approaches is a new and diverse field. This book provides a full coverage of the subject, introducing the fundamentals of cell membrane biology before exploring the key application areas.
Demystifies the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypesProvides a toolkit of micro- and nanoengineering approaches to the manipulation of the cell surfaceUnlocks the potential of cell surface manipulation for a range of new applications in the fields of in vitro research, cell therapy, tissue engineering, biosensing, and diagnostics"

Despite the enthusiasm surrounding the Colour Revolutions and the Arab Spring, the world's share of democracies has stagnated over the past 15 years. The steady rise of China, Russia, and Iran has also led to warnings of a resurgence of "authoritarian great powers", especially in light of the financial crisis centred in the USA and Western Europe. On the positive side, however, democracy remains remarkably popular as an ideal. In the Global barometer's most recent survey, two out of three respondents say democracy is their most favoured political system, including a majority in 49 of the 55 countries. Yet there is evidence, much expanded upon in this edited collection, that commitments to liberal democracy in practice are not as strong. Nominally pro-democratic citizens frequently favour limitations on electoral accountability and individual rights in the service of improved governance or economic growth. Further, there are rising concerns that many citizens, especially across the developing world, are turning away from democracy out of frustration with democratic performance. In contrast to many transitional regimes, the more established democracies appear to be losing support among their highly educated citizens. The contributions in this edited collection compare how democracy is understood and experienced in transitioning regimes and established democracies. This book was published as a special issue of the Journal of Elections, Public Opinion and Parties.

Despite the enthusiasm surrounding the Colour Revolutions and the Arab Spring, the world's share of democracies has stagnated over the past 15 years. The steady rise of China, Russia, and Iran has also led to warnings of a resurgence of "authoritarian great powers", especially in light of the financial crisis centred in the USA and Western Europe. On the positive side, however, democracy remains remarkably popular as an ideal. In the Global barometer's most recent survey, two out of three respondents say democracy is their most favoured political system, including a majority in 49 of the 55 countries. Yet there is evidence, much expanded upon in this edited collection, that commitments to liberal democracy in practice are not as strong. Nominally pro-democratic citizens frequently favour limitations on electoral accountability and individual rights in the service of improved governance or economic growth. Further, there are rising concerns that many citizens, especially across the developing world, are turning away from democracy out of frustration with democratic performance. In contrast to many transitional regimes, the more established democracies appear to be losing support among their highly educated citizens. The contributions in this edited collection compare how democracy is understood and experienced in transitioning regimes and established democracies. This book was published as a special issue of the Journal of Elections, Public Opinion and Parties.