|
Showing 1 - 25 of
109 matches in All Departments
The immune systems of human and non-human primates have diverged
over time, such that some species differ considerably in their
susceptibility, symptoms, and survival of particular infectious
diseases. Variation in primate immunity is such that major human
pathogens - such as immunodeficiency viruses, herpesviruses and
malaria-inducing species of"Plasmodium"- elicit striking
differences in immune response between closely related species and
within primate populations. These differences in immunity are the
outcome of complex evolutionary processes that include interactions
between the host, its pathogens and symbiont/commensal organisms.
The success of some pathogens in establishing persistent infections
inhumans and other primateshas been determined not just by the
molecular evolution of the pathogen and its interactions with the
host, but also by the evolution of primate behavior and ecology,
microflora, immune factors and the evolution of other biological
systems.
To explore how interactions between primates and their
pathogenshave shaped their mutual molecular evolution, "Primates,
Pathogens and Evolution"brings together research that
explorescomparativeprimate immune function, the emergence of major
and neglected primatediseases, primate-microorganism molecular
interactions, and related topics. Thisbookwill be of interest to
anyone curious as to why infectious diseases manifest differently
in humans and their closest relatives. It will be of particular
interest to scholars specializing in humanand non-human primate
evolution, epidemiology and immunology, and disease
ecology."Primates, Pathogens and Evolution"offers anoverview and
discussion of current findings on differences in the molecular
mechanics of primate immune response, as well as on
pathogen-mediated primate evolution and human and non-human primate
health."
Erythrocytes of the Rhesus and Cynomolgus Monkeys addresses the
morphologic, quantitative, and generative aspects of the
erythrocytes of the rhesus monkey Macaca mulatta and the cynomolgus
monkey Macaca fascicularis (long-tailed macaque, crab-eating
monkey). These two species are the most commonly selected nonhuman
primates for basic science and clinical medical investigations. The
hemopoietic cells of man and the rhesus monkey display an intimate
homogeneity. Their functional activities are close and at times
identical. The cynomolgus monkey was enlisted in biomedical studies
at a time when rhesus monkeys were not available in sufficient
quantities. It has gained increased use in the Far East and in the
Western world. It is, for example, employed in the current
development of a vaccine against the deadly Ebola virus. The
authors of the book discuss the erythropoietic profiles of normal
and abnormal macaques of both sexes and of all age groups as
investigated with contemporary electronic methodologies. They cover
the role of stress as it is perceived by the monkey and how it
impacts erythrocellular values, and how to train the monkey to be a
cooperative, unperturbed subject for hematologic study. Additional
topics include the role of medication in deriving normal
physiologic erythrocellular data, the development of the precursors
of the erythrocyte (normoblasts), the morphologic analysis of the
megaloblastic series of abnormal erythroid cells, the analysis of
erythropoiesis in bone marrow, the relationship of the simian
immunodeficiency virus and erythropoiesis, erythrocyte life span,
and parasitic invasion of the red cell.
|
|