OBJECTIVE: Analysis of beta blockers in formulated and unformulated samples demand a highly specific and rapid method as many beta blockers have serious stability problems. In the present Study, Analytical methods for the various Beta Blockers viz. Atenolol, Acebutolol, Bisoprolol, Betaxolol, Carvedilol, Nebivolol, Timolol, Sotalol etc. have been presented. A brief discussion on spectrum of activity and action mechanism of beta blocker has also been given. It include detail description of analysis of Beta blockers alone and in combined dosage form. A brief out line on current trend in method development and validation has also discussed in brief