The human pathogens Neisseria meningitidis and Neisseria gonorrhoeae are exquisitely adapted to life within the human mucosa, their only natural niche. N. meningitidis is the causative agent of rapidly transmissible meningitis and septic shock. Vaccines developed to control this pathogen can be rendered ineffective by the pathogen's ability to undergo antigenic variation. In contrast, there are no current vaccination prospects for N. gonorrhoeae, the causative agent of sexually transmitted gonorrhoea. Historically, infections caused by N. gonorrhoeae were treated with antibiotics. However, the recent advent of new strains with resistance to all known antibiotics is causing such treatment regimes to fail, necessitating the need for new and more effective control strategies. In this book, leading Neisseria authorities review the most important research on pathogenic Neisseria to provide a timely overview of the field. The topics covered include: the link between pathogenesis and important metabolic pathways * vaccine development * antibiotic resistance * transcriptomics of regulatory networks * regulatory small RNAs * interactions with neutrophils * advances in humanized mouse models. An essential guide for research scientists, advanced students, clinicians, and other professionals working with Neisseria, the book is a recommended text for all microbiology libraries.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

An all-new edition of the candid insiders' guide to the US Foreign Service as an institution, a profession, and a career Career Diplomacy takes readers inside the world of American diplomats in the US Foreign Service. Members of the Foreign Service represent the country abroad, protect and support American citizens overseas, manage government programs and facilities, and move foreign policy from the abstract to the actual. In this new and thoroughly revised edition, Foreign Service veterans Harry W. Kopp and John K. Naland lay out what to expect in a Foreign Service career, from the entrance exam through midcareer and into the senior service-how to get in, get around, and get ahead. Part one begins with the history and structure of the US Foreign Service in the Department of State and other agencies. Part two looks at a number of professional challenges, including how to be a diplomat in a war zone and how to respond when what the government demands conflicts with what the Constitution requires or one's conscience compels. In part three, the authors explore the trajectory of a Foreign Service career through their own experiences and through interviews with more than a hundred current and former members. Part four brings the discussion up to the present and looks to the future, describing a Service emerging from the Trump years determined to improve diversity in its workforce, protect a high standard of nonpolitical public service, and reward performance with responsibility. This best-selling guide demystifies the US Foreign Service for those interested in working within or alongside the institution. Kopp and Naland offer readers a candid look at the profession, with its dangers, rewards, challenges, frustrations, and excitement.

Peatlands form important landscape elements in many parts of the world and play significant roles for biodiversity and global carbon balance. This new edition has been fully revised and updated, documenting the latest advances in areas such as microbial processes and relations between biological processes and hydrology. As well as thoroughly referencing the latest research, the authors expose a rich older literature where an immense repository of natural history has accumulated. The Biology of Peatlands starts with an overview of the main peatland types (marsh, swamp, fen, and bog), before examining the entire range of biota present (microbes, invertebrates, plants, and vertebrates), together with their specific adaptations to peatland habitats. Detailed coverage is devoted to the genus Sphagnum, the most important functional plant group in northern peatlands, although tropical and southern hemisphere peatlands are also covered. Throughout the book the interactions between organisms and environmental conditions (especially wetness, availability of oxygen, and pH) are emphasized, with chapters on the physical and chemical characteristics of peat, the role of peat as an archive of past vegetation and climate, and peatland succession and development. Several other key factors and processes are then examined, including hydrology and nutrient cycling. The fascinating peatland landforms in different parts of the world are described, together with theories on how they have developed. Human interactions with peatlands are considered in terms of management, conservation, and restoration. A final chapter, new to this edition, focuses on the role of peatlands as sources or sinks for the greenhouse gases carbon dioxide and methane, and the influences of climate change on peatlands. This timely and accessible text is suitable for students and researchers of peatland ecology, as well as providing an authoritative overview for professional ecologists and conservation biologists.