The human pathogens Neisseria meningitidis and Neisseria gonorrhoeae are exquisitely adapted to life within the human mucosa, their only natural niche. N. meningitidis is the causative agent of rapidly transmissible meningitis and septic shock. Vaccines developed to control this pathogen can be rendered ineffective by the pathogen's ability to undergo antigenic variation. In contrast, there are no current vaccination prospects for N. gonorrhoeae, the causative agent of sexually transmitted gonorrhoea. Historically, infections caused by N. gonorrhoeae were treated with antibiotics. However, the recent advent of new strains with resistance to all known antibiotics is causing such treatment regimes to fail, necessitating the need for new and more effective control strategies. In this book, leading Neisseria authorities review the most important research on pathogenic Neisseria to provide a timely overview of the field. The topics covered include: the link between pathogenesis and important metabolic pathways * vaccine development * antibiotic resistance * transcriptomics of regulatory networks * regulatory small RNAs * interactions with neutrophils * advances in humanized mouse models. An essential guide for research scientists, advanced students, clinicians, and other professionals working with Neisseria, the book is a recommended text for all microbiology libraries.

Written by one of the astronomers who 'lived the dream' of working there this book is a restrospectively expanded diary featuring the 'birth and long life' of what was a truely innovative telescope. Based on input received from people involved in its planning, building, operation, and many scientists who observed with it, the author tells this success story of The United Kingdom Infrared Telescope (UKIRT). Conceived in the mid 1970's as a cheap and cheerful light-bucket for the newly emerging field of infrared astronomy it has re-invented itself once a decade to remain at the forefront of infrared astronomy for more than 30 years. Even in 2012 / 2013, when ironically it faced almost certain closure, it remained one of the most scientifically productive telescopes in the world. Everybody, including amateur and professional astronomers, interested in real astronomy projects will enjoy reading that story and meet (again) the persons who lived it.

A decade after the confirmation of the Kuiper Belt's existence, 80 of the world's experts gathered in Chile to review what has been learned since 1992. This record of the meeting is enhanced by several specially solicited papers covering additional material not presented at the conference. The volume includes papers on the dynamics of the trans-Neptunian region, the results of deep surveys for the new objects and the evidence for an outer Edge to the Edgeworth-Kuiper belt. Physical observations of many objects are described and attempts are made to bring these data into some coherent picture of the distant solar system. The interior physics of these distant, icy objects, and the link between the Kuiper Belt and dust disks around other stars are also considered. Of particular interest is a set of papers on how the surfaces of distant asteroids are affected by various types of radiation, an area crucial to the interpretation of data being collected by large ground based telescopes.
Suitable for professional astronomers and PhD students working in the field of planetary science.

The growth of health promotion as a topic for discussion and a principle for practice is widespread, and affects all groups of health professionals. The "Healthy Cities" project, like "Health for All", was inaugurated by the World Health Organization and has informed policy throughout the world. This volume examines the application of the project in a number of countries. The contributors explore problems in the relationship between policy makers, communities and academic researchers, and discuss how the "Healthy Cities" programme affects housing policy, commmunity development, scientific interchange and health education. In addition, John Davies and Michael Kelly provide a context by tracing the history of the WHO projects, and then discuss them in the broader context of scientific and philosophical debates about modernism and post-modernism. The contributors are drawn from practitioners and scientists with wide experience in this area from the United Kingdom, Canada, Australia and the United States.

Written by one of the astronomers who 'lived the dream' of working there this book is a restrospectively expanded diary featuring the 'birth and long life' of what was a truely innovative telescope. Based on input received from people involved in its planning, building, operation, and many scientists who observed with it, the author tells this success story of The United Kingdom Infrared Telescope (UKIRT). Conceived in the mid 1970's as a cheap and cheerful light-bucket for the newly emerging field of infrared astronomy it has re-invented itself once a decade to remain at the forefront of infrared astronomy for more than 30 years. Even in 2012 / 2013, when ironically it faced almost certain closure, it remained one of the most scientifically productive telescopes in the world. Everybody, including amateur and professional astronomers, interested in real astronomy projects will enjoy reading that story and meet (again) the persons who lived it.

This selection of essays by key names in the field of ancient economies in the 'Hellenistic' age (c.330-30BCE), provides essential reading for anyone interested in the evolutionary building blocks of economic history in the eastern Mediterranean and neighbouring regions. Case studies look at management and institutions; human mobility and natural resources; the role of different agents - temples and cities, as well as rulers - in enhancing resources and circulating wealth; the levers exerted by monopolies and by disparate status groups, including slaves. An introductory essay summarizes the operational elements that drove the engines of these economies.

The Making of Modern Law: Foreign, Comparative and International Law, 1600-1926, brings together foreign, comparative, and international titles in a single resource. Its International Law component features works of some of the great legal theorists, including Gentili, Grotius, Selden, Zouche, Pufendorf, Bijnkershoek, Wolff, Vattel, Martens, Mackintosh, Wheaton, among others. The materials in this archive are drawn from three world-class American law libraries: the Yale Law Library, the George Washington University Law Library, and the Columbia Law Library.Now for the first time, these high-quality digital scans of original works are available via print-on-demand, making them readily accessible to libraries, students, independent scholars, and readers of all ages.+++++++++++++++The below data was compiled from various identification fields in the bibliographic record of this title. This data is provided as an additional tool in helping to insure edition identification: +++++++++++++++Harvard Law School LibraryLP2H009780019000101The Making of Modern Law: Primary Sources, Part II Cedartown, Ga.?]: The City?], 1900]149 p.; 23 cmUnited States