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The discovery of biological activity associated with flavonoid
contaminants in vitamin C preparations from bell peppers and lemons
by Szent-Gyorgyi and his associates opened a floodgate of research
into the biological functions of this ubiquitous and diverse group
of compounds. Since then, a broad range of physiological and
biochemical activities were discovered in living systems including
most plants and animals. With the continued discovery, isolation
and identification of new natural and synthetic compounds
exhibiting biological activities, entire research programs are
devoted to wide ranging investigations to nearly every conceivable
area, from microbial and plant interaction, growth regulation and
development to physiological, genetical, medicinal actions and uses
in animals. This volume is based on presentations made at a
Symposium, titled Flavonoids in Cell Function, held during the
219'h National Meeting of the American Chemical Society held in San
Francisco, California on March 29-30, 2000. The book is not
intended to be a comprehensive treatise on flavonoid research, only
a sampling of recent results. The papers cover a range of topics
discussing various approaches to flavonoid study, starting at plant
microbe communication through analytical methods to medicinal and
systemic implications of these compounds in animal cells and
systems. The organizers would like to express their thanks to
Cargill Foods, Inc., Minneapolis, Minnesota and the Division of
Agricultural and Food Chemistry of the American Chemical Society
for financial support. A great deal of thanks is also due to the
authors without whose cooperation and patience this volume would
not be realized.
Flavonoids in the Living System: An Introduction; J.A.Manthey, B.S.
Buslig. Flavonoids and Arbucular-Mycorrhizal Fungi; H. Vierheilig,
et al the Role of Glycosylation in Flavonol-Induced Pollen
Germination; L.P. Taylor, et al. Expression of Genes for Enzymes of
the Flavonoid Biosynthetic Pathway in the Early Stages of the
Rhizobium-Legume Symbiosis; H.I. McKhann, et al. Prospects for the
Metabolic Engineering of Bioactive Flavonoids and Related
Phenylpropanoid Compounds; R.A. Dixon, et al. Flavonoid
Accumulation in Tissue and Cell Culture; Studies in Citrus and
other Plant Species; M.A. Berhow. Flavonoids of the Orange
Subfamily Aurantioideae; J.A. Manthey, K. Grohmann. Citrus
Flavonoids: A Review of Past Biological Activity Against Disease:
Discovery of New Flavonoids from Dancy Tangerine Cold Pressed Peel
Oil Solids and Leaves; A. Montanari, et al. Differentiation of Soy
Sauce Types by HPLC Profile Pattern Recognition: Isolation of Novel
Isoflavones; E. Kinoshita, et al. Induction of Oxidative Stress by
Redox Active Flavonoids; W.F. Hodnick, et al. Flavonoids in Foods
as in Vitro and in Vivo Antioxidants; J.A. Vinson. 7 Additional
Chapters. Index.
The presence of contaminant flavonoids in vitamin C preparations
from citrus fruits initially led Szent-Gyorgyi and his
collaborators to suggest that a flavonoid compound, with biological
activity for the prevention of capillary fragility, was vitamin P.
Later re search, although not disproving biological activity,
discontinued the use of the vitamin classification for these
compounds. However, the ubiquitous distribution of flavonoids in
living organisms, and the continued discovery of various activity
in biological systems makes these compounds targets of wide ranging
investigation. This volume is primarily based on a Symposium on
Flavonoids and related com pounds held during the 212th National
Meeting of the American Chemical Society held in Orlando, Florida
on August 28-29, 1996 under the sponsorship of the Division of
Agricul tural and Food Chemistry. While the book is not intended to
be a comprehensive volume on flavonoid research, the papers provide
various approaches to exploring the biological functions of
flavonoids in plants and animals, their chemical modifications for
enhanced activity, some analytical techniques, as well as their use
in food classification. A signifi cant portion is devoted to
medicinal implications of these compounds. The organizers would
like to express their appreciation to Tropicana Products, Inc.,
Bradenton, Florida, Coca-Cola Foods Division, Plymouth, Florida and
the American Chemical Society's Division of Agricultural and Food
Chemistry for financial support. Of course, the book could not be
produced without the authors, whose cooperation and pa tience is
greatly appreciated.
The discovery of biological activity associated with flavonoid
contaminants in vitamin C preparations from bell peppers and lemons
by Szent-Gyorgyi and his associates opened a floodgate of research
into the biological functions of this ubiquitous and diverse group
of compounds. Since then, a broad range of physiological and
biochemical activities were discovered in living systems including
most plants and animals. With the continued discovery, isolation
and identification of new natural and synthetic compounds
exhibiting biological activities, entire research programs are
devoted to wide ranging investigations to nearly every conceivable
area, from microbial and plant interaction, growth regulation and
development to physiological, genetical, medicinal actions and uses
in animals. This volume is based on presentations made at a
Symposium, titled Flavonoids in Cell Function, held during the
219'h National Meeting of the American Chemical Society held in San
Francisco, California on March 29-30, 2000. The book is not
intended to be a comprehensive treatise on flavonoid research, only
a sampling of recent results. The papers cover a range of topics
discussing various approaches to flavonoid study, starting at plant
microbe communication through analytical methods to medicinal and
systemic implications of these compounds in animal cells and
systems. The organizers would like to express their thanks to
Cargill Foods, Inc., Minneapolis, Minnesota and the Division of
Agricultural and Food Chemistry of the American Chemical Society
for financial support. A great deal of thanks is also due to the
authors without whose cooperation and patience this volume would
not be realized.
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