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Bhowani Junction is set in the wake of the partition of India, as
the British prepare to withdraw from the newly independent country.
Evoking the tensions and conflicts that accompanied the birth of
modern India, the characters struggle to find their place in the
new India that is emerging. In the last hectic days of the British
Raj, Victoria has to choose between marrying a British Army officer
or a Sikh, Ranjit, as she struggles to find her place in the new,
independent India. One of John Masters' seven novels which followed
several generations of the Savage family serving in the British
Army in India, it is Masters' most famous novel, and was made into
a film in 1956, starring Ava Gardener and Stewart Granger.
The aim of volume 7 of Human Cell Culture is to provide clear
and precise methods for growing primary cultures of adult stem
cells from various human tissues and describe culture conditions in
which these adult stem cells differentiate along their respective
lineages. The book will be of value to biomedical scientists and of
special interest to stem cell biologists and tissue engineers. Each
chapter is written by experts actively involved in growing human
adult stem cells.
Continuous cell lines derived from human cancers are the mostwidely
used resource in laboratory-based cancer research. The first 3
volumes of this series on Human Cell Culture are devoted to these
cancer cell lines. The chapters in these first 3 volumes have a
common aim. Their purpose is to address 3 questions offundamental
importance to the relevanceof human cancer cell lines as model
systems of each type of cancer: 1. Do the cell lines available
accurately represent the clinical presentation? 2. Do the cell
lines accurately represent the histopathology of the original
tumors? 3. Do the cell lines accurately represent the molecular
genetics of this type of cancer? The cancer cell lines available
are derived, in most cases, from the more aggressive and advanced
cancers. There are few cell lines derived from low grade
organ-confined cancers. This gap can be filled with conditionally
immortalized human cancer cell lines. We do not know why the
success rate for establishing cell lines is so low for some types
of cancer and so high for others. The histopathology of the tumor
of origin and the extent to which the derived cell line retains the
differentiated features of that tumor are critical. The concept
that a single cell line derived from a tumor at a particular site
is representative oftumors at that site is naive and misleading."
The human body contains many specialized tissues that are capable
of fulfilling an incredible variety of functions necessary for our
survival. This volume in the Human Cell Culture Series focuses on
mesenchymal tissues and cells. The in vitro study of mesenchymal
cells is perhaps the oldest form of human cell culture, beginning
with the culturing of fibroblasts. Fibroblasts have long been
generically described in the literature, arising from many tissue
types upon in vitro cell culture. However, recent studies, many
enabled by new molecular biology techniques, have shown
considerable diversity in fibroblast type and function, as
described within this volume. Mesenchymal tissue types that are
described within include bone, cartilage, tendons and ligaments,
muscle, adipose tissue, and skin (dermis). The proper function of
these tissues is predominantly dependent upon the proper
proliferation, differentiation, and function of the mesenchymal
cells which make up the tissue. Recent advancements in primary
human mesenchymal cell culture have led to remarkable progress in
the study of these tissues. Landmark experiments have now
demonstrated a stem cell basis for many of these tissues, and,
furthermore, significant plasticity and inter-conversion of stem
cells between these tissues, resulting in a great deal of
contemporary excitement and controversy. Newly-developed
mesenchymal cell culture techniques have even lead to novel
clinical practices for the treatment of disease.
This book describes all human leukemia-lymphoma cell lines that
have been established and that grow continuously under standardised
in vitro conditions. These lines are derived from cells belonging
to all the major hematopoietic cell lineages, i.e. B- and
T-lymphocytes, natural killer cells, granulocytic cells and
megakaryocytic cells. The clinical data, the culture conditions and
the major phenotypic features of the cell lines are described with
citations. This book is the first book describing human
leukemia-lymphoma cell lines and will be of interest to scientists
involved in the areas of hematology, oncology, immunology,
molecular biology and cytogenetics. Cancer Cell Lines, Volumes 1-3:
These 3 volumes provide a comprehensive text on the culture of
established cell lines from every type of human cancer. The volumes
provide a basic manual and reference resource for every cancer
research scientist using human cancer cells.
Continuous cell lines derived from human cancers are the most
widely used resource in laboratory-based cancer research. The first
3 volumes of this series on Human Cell Culture are devoted to these
cancer cell lines. The chapters in these first 3 volumes have a
common aim. Their purpose is to address 3 questions of fundamental
importance to the relevance of human cancer cell lines as model
systems of each type of cancer: 1. Do the cell lines available
accurately represent the clinical presentation? 2. Do the cell
lines accurately represent the histopathology of the original
tumors? 3. Do the cell lines accurately represent the molecular
genetics of this type of cancer? The cancer cell lines available
are derived, in most cases, from the more aggressive and advanced
cancers. There are few cell lines derived from low grade
organ-confined cancers. This gap can be filled with conditionally
immortalized human cancer cell lines. We do not know why the
success rate for establishing cell lines is so low for some types
of cancer and so high for others. The histopathology of the tumor
of origin and the extent to which the derived cell line retains the
differentiated features of that tumor are critical. The concept
that a single cell line derived from a tumor at a particular site
is representative of tumors at that site is naive and misleading."
In 1825 William Savage is an official in the East India Company,
committed to the people of his remote district and British rule in
India. During the course of his duties he witnesses a double murder
and stumbles upon the society of the thuggee, a secret cult that
has flourished in India for 200 years and murdered over a million
people. When Savage discovers a mass grave, including the body of a
recently killed British officer, his investigation leads him to
infiltrate, while disguised, the cult. He learns their secrets but
finds himself drawn to the ecstasy of ritual killing. Can his sense
of honour prevail, can he destroy the thuggees?
Growing human cancer cells in primary culture requires patience,
intuition, care and experience. This is one of the few areas where
the wrinkled senior scientist can be more productive than the
bright young post-doc. There are few mechanical aids, no automated
procedures, and kits are unheard-of. There is no right way to do it
and every tumour is different. But this book will make it easier
Chapter 1 on characterization is essential reading. Much published
work is useless because of the failure to take two simple steps to
characterise the cells. The first step is to fully record all the
clinical data - the absence of this information can render the work
valueless. The second step is to confirm the origin of the tissue
to exclude cross contamination. The wastage of years of work can be
avoided with the use of a simple DNA preparation with a couple of
commercially-available probes. Chapter 2 describes the development
of serum-free media. This is a goal many would like to achieve,
particularly if someone else does it, as it is laborious and
empirical. Defined serum-free medium is essential for studies of
growth factors and has major advantages in the commercial
preparation of cell products and other applications."
This book describes all human leukemia-lymphoma cell lines that
have been established and that grow continuously under standardised
in vitro conditions. These lines are derived from cells belonging
to all the major hematopoietic cell lineages, i.e. B- and
T-lymphocytes, natural killer cells, granulocytic cells and
megakaryocytic cells. The clinical data, the culture conditions and
the major phenotypic features of the cell lines are described with
citations. This book is the first book describing human
leukemia-lymphoma cell lines and will be of interest to scientists
involved in the areas of hematology, oncology, immunology,
molecular biology and cytogenetics. Cancer Cell Lines, Volumes 1-3:
These 3 volumes provide a comprehensive text on the culture of
established cell lines from every type of human cancer. The volumes
provide a basic manual and reference resource for every cancer
research scientist using human cancer cells.
Continuous cell lines derived from human cancers are the mostwidely
used resource in laboratory-based cancer research. The first 3
volumes of this series on Human Cell Culture are devoted to these
cancer cell lines. The chapters in these first 3 volumes have a
common aim. Their purpose is to address 3 questions offundamental
importance to the relevanceof human cancer cell lines as model
systems of each type of cancer: 1. Do the cell lines available
accurately represent the clinical presentation? 2. Do the cell
lines accurately represent the histopathology of the original
tumors? 3. Do the cell lines accurately represent the molecular
genetics of this type of cancer? The cancer cell lines available
are derived, in most cases, from the more aggressive and advanced
cancers. There are few cell lines derived from low grade
organ-confined cancers. This gap can be filled with conditionally
immortalized human cancer cell lines. We do not know why the
success rate for establishing cell lines is so low for some types
of cancer and so high for others. The histopathology of the tumor
of origin and the extent to which the derived cell line retains the
differentiated features of that tumor are critical. The concept
that a single cell line derived from a tumor at a particular site
is representative oftumors at that site is naive and misleading."
The aim of volume 7 of Human Cell Culture is to provide clear
and precise methods for growing primary cultures of adult stem
cells from various human tissues and describe culture conditions in
which these adult stem cells differentiate along their respective
lineages. The book will be of value to biomedical scientists and of
special interest to stem cell biologists and tissue engineers. Each
chapter is written by experts actively involved in growing human
adult stem cells.
John Masters was a soldier before he became a novelist. Born in
India, he was sent to England to complete his education before
attending Sandhurst. It was there the rumour began about his
ancestry, that (in the language of the time) he 'had a touch of the
tarbrush'. This encounter with racist bigotry would be turned to
good effect in his novel, "Bhowani Junction" (later filmed with
Stewart Granger and Ava Gardner). At Sandhurst it just made him
more determined to succeed. John Masters joined a Gurhka regiment
on receiving his commission. Here, He depicts garrison life and
campaigning on the North-West Frontier.
The second part of John Masters' autobiography: how he fought with
his Gurkha regiment during World War II until his promotion to
command one of the Chindit columns behind enemy lines in Burma.
This is a moving story that culminates in him having personally to
shoot a number of wounded British soldiers who could not be
evacuated before their position was overrun by the Japanese. It is
an uncomfortable reminder that Churchill's obsession with "special
forces" squandered thousands of Allied lives in operations that
owed more to public relations than strategic calculation.
Continuous cell lines derived from human cancers are the most
widely used resource in laboratory-based cancer research. The first
3 volumes of this series on Human Cell Culture are devoted to these
cancer cell lines. The chapters in these first 3 volumes have a
common aim. Their purpose is to address 3 questions of fundamental
importance to the relevance of human cancer cell lines as model
systems of each type of cancer: 1. Do the cell lines available
accurately represent the clinical presentation? 2. Do the cell
lines accurately represent the histopathology of the original
tumors? 3. Do the cell lines accurately represent the molecular
genetics of this type of cancer? The cancer cell lines available
are derived, in most cases, from the more aggressive and advanced
cancers. There are few cell lines derived from low grade
organ-confined cancers. This gap can be filled with conditionally
immortalized human cancer cell lines. We do not know why the
success rate for establishing cell lines is so low for some types
of cancer and so high for others. The histopathology of the tumor
of origin and the extent to which the derived cell line retains the
differentiated features of that tumor are critical. The concept
that a single cell line derived from a tumor at a particular site
is representative of tumors at that site is naive and misleading."
This new edition of Animal Cell Culture covers new or updated chapters on cell authentication, serum-free culture, apoptosis assays, FISH, genetic modification, scale-up, stem cell assays, 3-dimensional culture, tissue engineering and cytotoxicity assays. Detailed protocols for a wide variety of methods provide the core of each chapter, making new methodology easily accessible. Everyone working in biological and medical research, whether in academia or a commercial organization, practising cell culture will benefit greatly from this book.
First published in 1951, The Nightrunners of Bengal is one of John
Masters' series of seven novels which followed several generations
of the Savage family serving in the British Army in India.
Nightrunners of Bengal focuses on the Indian Rebellion of 1857. The
central character, Captain Rodney Savage, is an officer in a Bengal
Native Infantry regiment, based in the fictional city of Bhowani.
When rebellion breaks out, the British community in Bengal is
shattered. Savage's empathy for the Indians is shaken, as the
British try to discover who is loyal to them and who is not. One of
the great novels of India, Nightrunners of Bengal combines John
Master's mastery of story-telling with an intuitive sense of
history. This was the first novel that Masters wrote in the series,
though not the first novel chronologically, and alongside Bhowani
Junction is one of his best-known works.
Title: The Ponderer, a series of essays; biographical, literary,
moral and critical. (Originally published in the British
Mercury.).Publisher: British Library, Historical Print EditionsThe
British Library is the national library of the United Kingdom. It
is one of the world's largest research libraries holding over 150
million items in all known languages and formats: books, journals,
newspapers, sound recordings, patents, maps, stamps, prints and
much more. Its collections include around 14 million books, along
with substantial additional collections of manuscripts and
historical items dating back as far as 300 BC.The FICTION &
PROSE LITERATURE collection includes books from the British Library
digitised by Microsoft. The collection provides readers with a
perspective of the world from some of the 18th and 19th century's
most talented writers. Written for a range of audiences, these
works are a treasure for any curious reader looking to see the
world through the eyes of ages past. Beyond the main body of works
the collection also includes song-books, comedy, and works of
satire. ++++The below data was compiled from various identification
fields in the bibliographic record of this title. This data is
provided as an additional tool in helping to insure edition
identification: ++++ British Library Evans, John Master of the
Academy Kingsdown. 1812 12 . 12269.c.3.
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