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On the Warming of Houses, Paper (Paperback): John Pollard Seddon On the Warming of Houses, Paper (Paperback)
John Pollard Seddon
R312 Discovery Miles 3 120 Ships in 12 - 17 working days
In Search of Shipki La (Hardcover): John Pollard In Search of Shipki La (Hardcover)
John Pollard
R1,051 Discovery Miles 10 510 Ships in 12 - 17 working days

When a young American draft dodger from the Vietnam War disappears, his anxious parents seek the help of a Buffalo, New York, investigation company. The last coded postcard they received from their son indicated that he was hiding out in Afghanistan. The investigator photographs two bearded American young men camped in Kabul arguing with a better-dressed Englishman, but neither is the missing son. The trail goes cold. Thirty-five years later, a western Australian friend of the widowed mother uncovers the names of an Australian couple who were camped in Kabul at the time and might be able to provide clues to the young man's disappearance. The search is renewed, taking the investigators to Pakistan, the Indian Himalayas, the red-light area of Bangkok, and to the neighboring Laos.

Memoir and Letters of the Late Thomas Seddon, Artist: John Pollard Seddon Thomas Seddon Memoir and Letters of the Late Thomas Seddon, Artist
John Pollard Seddon Thomas Seddon
R843 Discovery Miles 8 430 Ships in 12 - 17 working days
The Papacy in the Age of Totalitarianism, 1914-1958 (Hardcover): John Pollard The Papacy in the Age of Totalitarianism, 1914-1958 (Hardcover)
John Pollard
R3,799 Discovery Miles 37 990 Ships in 12 - 17 working days

The Papacy in the Age of Totalitarianism, 1914-1958 examines the most momentous years in papal history. Popes Benedict XV (1914-1922), Pius XI (1922-1939), and Pius XII (1939-1958) faced the challenges of two world wars and the Cold War, and threats posed by totalitarian dictatorships like Italian Fascism, German National Socialism, and Communism in Russia and China. The wars imposed enormous strains upon the unity of Catholics and the hostility of the totalitarian regimes to Catholicism lead to the Church facing persecution and martyrdom on a scale similar to that experienced under the Roman Empire and following the French Revolution. At the same time, these were years of growth, development, and success for the papacy. Benedict healed the wounds left by the 'modernist' witch hunt of his predecessor and re-established the papacy as an influence in international affairs through his peace diplomacy during the First World War. Pius XI resolved the 'Roman Question' with Italy and put papal finances on a sounder footing. He also helped reconcile the Catholic Church and science by establishing the Pontifical Academy of Sciences and took the first steps to move the Church away from entrenched anti-Semitism. Pius XI continued his predecessor's policy of the 'indigenisation' of the missionary churches in preparation for de-colonisation. Pius XII fully embraced the media and other means of publicity, and with his infallible promulgation of the Assumption in 1950, he took papal absolutism and centralism to such heights that he has been called the 'last real pope'. Ironically, he also prepared the way for the Second Vatican Council.

Targeting the DNA Damage Response for Anti-Cancer Therapy (Hardcover, 1st ed. 2018): John Pollard, Nicola Curtin Targeting the DNA Damage Response for Anti-Cancer Therapy (Hardcover, 1st ed. 2018)
John Pollard, Nicola Curtin
R6,436 Discovery Miles 64 360 Ships in 12 - 17 working days

Over the past decade a complex role for DNA damage response (DDR) in tumorigenesis has emerged. A proficient DDR has been shown to be a primary cause for cellular resistance to the very many DNA damaging drugs, and IR, that are widely used as standard-of-care across multiple cancer types. It has also been shown that defects in this network, predominantly within the ATM mediated signaling pathway, are commonly observed in cancers and may be a primary event during tumorigenesis. Such defects may promote a genomically unstable environment, facilitating the persistence of mutations, any of which may provide a growth or survival advantage to the developing tumor. In addition, these somatic defects provide opportunities to exploit a reliance on remaining repair pathways for survival, a process which has been termed synthetic lethality. As a result of all these observations there has been a great interest in targeting the DDR to provide anti-cancer agents that may have benefit as monotherapy in cancers with high background DNA damage levels or as a means to increase the efficacy of DNA damaging drugs and IR. In this book we will review a series of important topics that are of great interest to a broad range of academic, industrial and clinical researchers, including the basic science of the DDR, its role in tumorigenesis and in dictating response to DNA damaging drugs and IR. Additionally, we will focus on the several proteins that have been targeted in attempts to provide drug candidates, each of which appear to have quite distinct profiles and could represent very different opportunities to provide patient benefit.

Catholicism in Modern Italy - Religion, Society and Politics since 1861 (Paperback): John Pollard Catholicism in Modern Italy - Religion, Society and Politics since 1861 (Paperback)
John Pollard
R1,648 Discovery Miles 16 480 Ships in 12 - 17 working days

John Pollard's book surveys the relationship between Catholicism and the process of change in Italy from Unification to the present day. Central to the book is the complex set of relationships between traditional religion and the forces of change. In a broad sweep, Catholicism in Modern Italy looks at the cultural, social, political and economic aspects of the Catholic church and its relationship to the different experiences across Italy over this dramatic period of change and 'modernisation'.

Catholicism in Modern Italy - Religion, Society and Politics since 1861 (Hardcover, New): John Pollard Catholicism in Modern Italy - Religion, Society and Politics since 1861 (Hardcover, New)
John Pollard
R4,275 Discovery Miles 42 750 Ships in 12 - 17 working days

John Pollard's book surveys the relationship between Catholicism and the process of change in Italy from Unification to the present day. Central to the book is the complex set of relationships between traditional religion and the forces of change. In a broad sweep, Catholicism in Modern Italy looks at the cultural, social, political and economic aspects of the Catholic church and its relationship to the different experiences across Italy over this dramatic period of change and 'modernisation'.

Shelley's political thought (Hardcover, Reprint 2015): John Pollard Guinn Shelley's political thought (Hardcover, Reprint 2015)
John Pollard Guinn
R3,402 Discovery Miles 34 020 Ships in 12 - 17 working days
The Fascist Experience in Italy (Hardcover, New): John Pollard The Fascist Experience in Italy (Hardcover, New)
John Pollard
R3,251 Discovery Miles 32 510 Ships in 12 - 17 working days

This work examines the development of Italian fascism, and surveys the themes and issues of the movement. It covers from the emergence of the united Italian state and the political, social and economic status of Italy in the 19th century, to the post-war aftermath of fascism. The book provides: analysis of printed and broadcast propaganda as well as Mussolini's journalism; documentary material, previously unavailable in English; an extensive range of other source material, including images; and thematic coverage of major topics such as the transformation of Italian agrarian and urban society and the actions of the Papacy. John Pollard includes fully integrated analysis and extensive notes on sources as well as a glossary and guide to further reading. He reassesses the status of the fascist movement as a coalition rather than a monolith and details the images of energy and violence which were crucial to the success of fascism, both within Italy and internationally.

The Fascist Experience in Italy (Paperback, New): John Pollard The Fascist Experience in Italy (Paperback, New)
John Pollard
R1,146 Discovery Miles 11 460 Ships in 12 - 17 working days


This book examines the development of Italian Fascism, and surveys the themes and issues of the movement. It covers from the emergence of the united Italian state and the political, social and economic status of Italy in the nineteenth century, to the post-war aftermath of fascism. The Fascist Experience in Italy provides:
* analysis of printed and broadcast propaganda as well as Mussolini's journalism
* new documentary material, previously unavailable in English
* an extensive range of other source material, including images
* thematic coverage of major topics such as the transformation of Italian agrarian and urban society and the actions of the Papacy.
John Pollard includes fully integrated analysis and extensive notes on sources as well as a glossary and guide to further reading. He reassesses the status of the fascist movement as a coalition rather than a monolith and details the images of energy and violence which were crucial to the success of fascism, both within Italy and internationally.

The Papacy in the Age of Totalitarianism, 1914-1958 (Paperback): John Pollard The Papacy in the Age of Totalitarianism, 1914-1958 (Paperback)
John Pollard
R1,315 Discovery Miles 13 150 Ships in 12 - 17 working days

The Papacy in the Age of Totalitarianism, 1914-1958 examines the most momentous years in papal history. Popes Benedict XV (1914-1922), Pius XI (1922-1939), and Pius XII (1939-1958) faced the challenges of two world wars and the Cold War, and threats posed by totalitarian dictatorships like Italian Fascism, German National Socialism, and Communism in Russia and China. The wars imposed enormous strains upon the unity of Catholics and the hostility of the totalitarian regimes to Catholicism lead to the Church facing persecution and martyrdom on a scale similar to that experienced under the Roman Empire and following the French Revolution. At the same time, these were years of growth, development, and success for the papacy. Benedict healed the wounds left by the 'modernist' witch hunt of his predecessor and re-established the papacy as an influence in international affairs through his peace diplomacy during the First World War. Pius XI resolved the 'Roman Question' with Italy and put papal finances on a sounder footing. He also helped reconcile the Catholic Church and science by establishing the Pontifical Academy of Sciences and took the first steps to move the Church away from entrenched anti-Semitism. Pius XI continued his predecessor's policy of the 'indigenisation' of the missionary churches in preparation for de-colonisation. Pius XII fully embraced the media and other means of publicity, and with his infallible promulgation of the Assumption in 1950, he took papal absolutism and centralism to such heights that he has been called the 'last real pope'. Ironically, he also prepared the way for the Second Vatican Council.

Targeting the DNA Damage Response for Anti-Cancer Therapy (Paperback, Softcover reprint of the original 1st ed. 2018): John... Targeting the DNA Damage Response for Anti-Cancer Therapy (Paperback, Softcover reprint of the original 1st ed. 2018)
John Pollard, Nicola Curtin
R5,604 Discovery Miles 56 040 Ships in 10 - 15 working days

Over the past decade a complex role for DNA damage response (DDR) in tumorigenesis has emerged. A proficient DDR has been shown to be a primary cause for cellular resistance to the very many DNA damaging drugs, and IR, that are widely used as standard-of-care across multiple cancer types. It has also been shown that defects in this network, predominantly within the ATM mediated signaling pathway, are commonly observed in cancers and may be a primary event during tumorigenesis. Such defects may promote a genomically unstable environment, facilitating the persistence of mutations, any of which may provide a growth or survival advantage to the developing tumor. In addition, these somatic defects provide opportunities to exploit a reliance on remaining repair pathways for survival, a process which has been termed synthetic lethality. As a result of all these observations there has been a great interest in targeting the DDR to provide anti-cancer agents that may have benefit as monotherapy in cancers with high background DNA damage levels or as a means to increase the efficacy of DNA damaging drugs and IR. In this book we will review a series of important topics that are of great interest to a broad range of academic, industrial and clinical researchers, including the basic science of the DDR, its role in tumorigenesis and in dictating response to DNA damaging drugs and IR. Additionally, we will focus on the several proteins that have been targeted in attempts to provide drug candidates, each of which appear to have quite distinct profiles and could represent very different opportunities to provide patient benefit.

The Unknown Pope - Benedict XV (1912-1922) and the Pursuit of Peace (Paperback): John Pollard The Unknown Pope - Benedict XV (1912-1922) and the Pursuit of Peace (Paperback)
John Pollard
R1,405 Discovery Miles 14 050 Ships in 10 - 15 working days

Best known for his efforts to end World War I. Benedict XV was the first contemporary pope to assume the role of peacemaker, a role that has persisted in the papacy since. Although Benedict's 1917 "Peace Note" was rejected by officials, he went on to help establish Save the Children and to lead European efforts at humanitarian aid. His brief pontificate resulted in a positive reassessment of the Church's attitude towards colonialism and colonized peoples. Using previously unpublished correspondence and private papers from the Vatican archives, John Pollard has written the first biography on Benedict XV in almost half a century.

Memoir and Letters of the Late Thomas Seddon, Artist (Paperback): John Pollard Seddon Thomas Seddon Memoir and Letters of the Late Thomas Seddon, Artist (Paperback)
John Pollard Seddon Thomas Seddon
R574 Discovery Miles 5 740 Ships in 10 - 15 working days
Call Him Savage (Paperback): John Pollard Call Him Savage (Paperback)
John Pollard
R417 R361 Discovery Miles 3 610 Save R56 (13%) Ships in 10 - 15 working days
Rambles In The Rhine Provinces (Paperback): John Pollard Seddon Rambles In The Rhine Provinces (Paperback)
John Pollard Seddon
R574 Discovery Miles 5 740 Ships in 10 - 15 working days
A Visit to the Architectural Museum - Written for Students: Talbot collection of British pamphlets (Paperback): John Pollard... A Visit to the Architectural Museum - Written for Students: Talbot collection of British pamphlets (Paperback)
John Pollard Seddon, Thomas Raffles Davison
R352 Discovery Miles 3 520 Ships in 10 - 15 working days
Progress in Art and Architecture - With Precedents for Ornament (Hardcover): John Pollard Seddon Progress in Art and Architecture - With Precedents for Ornament (Hardcover)
John Pollard Seddon
R808 Discovery Miles 8 080 Ships in 10 - 15 working days
Essays And Lectures On Medical Subjects (Hardcover): John Pollard Harrison Essays And Lectures On Medical Subjects (Hardcover)
John Pollard Harrison
R851 Discovery Miles 8 510 Ships in 10 - 15 working days
Anthology of Sci-Fi V36, the Pulp Writers (Paperback): Howard Carleton Browne, John Pollard, Darius John Granger Anthology of Sci-Fi V36, the Pulp Writers (Paperback)
Howard Carleton Browne, John Pollard, Darius John Granger
R444 Discovery Miles 4 440 Ships in 10 - 15 working days
Progress in Art and Architecture - With Precedents for Ornament... (Paperback): John Pollard Seddon Progress in Art and Architecture - With Precedents for Ornament... (Paperback)
John Pollard Seddon
R490 R408 Discovery Miles 4 080 Save R82 (17%) Ships in 10 - 15 working days

This is a reproduction of a book published before 1923. This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book. ++++ The below data was compiled from various identification fields in the bibliographic record of this title. This data is provided as an additional tool in helping to ensure edition identification: ++++ Progress In Art And Architecture: With Precedents For Ornament John Pollard Seddon D. Bogue, 1852 Art; Design; Decorative; Architecture, Gothic; Art / Design / Decorative; Decoration and ornament

Memoir and Letters of the Late Thomas Seddon, Artist (1858) (Hardcover): Thomas Seddon Memoir and Letters of the Late Thomas Seddon, Artist (1858) (Hardcover)
Thomas Seddon; Edited by John Pollard Seddon
R860 Discovery Miles 8 600 Out of stock

This scarce antiquarian book is a selection from Kessinger Publishing's Legacy Reprint Series. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment to protecting, preserving, and promoting the world's literature. Kessinger Publishing is the place to find hundreds of thousands of rare and hard-to-find books with something of interest for everyone

Rambles in the Rhine Provinces Illustrated with Chromo-Lithographs, Photographs, and Wood-Engravings. (Paperback): John Pollard... Rambles in the Rhine Provinces Illustrated with Chromo-Lithographs, Photographs, and Wood-Engravings. (Paperback)
John Pollard Seddon
R661 R557 Discovery Miles 5 570 Save R104 (16%) Ships in 10 - 15 working days

Title: Rambles in the Rhine Provinces ... Illustrated with chromo-lithographs, photographs, and wood-engravings.Publisher: British Library, Historical Print EditionsThe British Library is the national library of the United Kingdom. It is one of the world's largest research libraries holding over 150 million items in all known languages and formats: books, journals, newspapers, sound recordings, patents, maps, stamps, prints and much more. Its collections include around 14 million books, along with substantial additional collections of manuscripts and historical items dating back as far as 300 BC.The HISTORY OF EUROPE collection includes books from the British Library digitised by Microsoft. This collection includes works chronicling the development of Western civilisation to the modern age. Highlights include the development of language, political and educational systems, philosophy, science, and the arts. The selection documents periods of civil war, migration, shifts in power, Muslim expansion into Central Europe, complex feudal loyalties, the aristocracy of new nations, and European expansion into the New World. ++++The below data was compiled from various identification fields in the bibliographic record of this title. This data is provided as an additional tool in helping to insure edition identification: ++++ British Library Seddon, John Pollard; 1867]. 4 . 10240.k.11.

Rambles In The Rhine Provinces (1868) (Paperback): John Pollard Seddon Rambles In The Rhine Provinces (1868) (Paperback)
John Pollard Seddon
R748 Discovery Miles 7 480 Ships in 10 - 15 working days

This scarce antiquarian book is a selection from Kessinger Publishing's Legacy Reprint Series. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment to protecting, preserving, and promoting the world's literature. Kessinger Publishing is the place to find hundreds of thousands of rare and hard-to-find books with something of interest for everyone!

Memoir and Letters of the Late Thomas Seddon, Artist (1858) (Paperback): Thomas Seddon Memoir and Letters of the Late Thomas Seddon, Artist (1858) (Paperback)
Thomas Seddon; Edited by John Pollard Seddon
R711 Discovery Miles 7 110 Ships in 10 - 15 working days

This scarce antiquarian book is a selection from Kessinger Publishing's Legacy Reprint Series. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment to protecting, preserving, and promoting the world's literature. Kessinger Publishing is the place to find hundreds of thousands of rare and hard-to-find books with something of interest for everyone

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