0
Your cart

Your cart is empty

Browse All Departments
  • All Departments
Price
  • R100 - R250 (1)
  • R500 - R1,000 (1)
  • R2,500 - R5,000 (3)
  • -
Status
Brand

Showing 1 - 5 of 5 matches in All Departments

Preclinical Evaluation of Antimicrobial Nanodrugs (Hardcover, 1st ed. 2020): Juan Bueno Preclinical Evaluation of Antimicrobial Nanodrugs (Hardcover, 1st ed. 2020)
Juan Bueno
R2,789 Discovery Miles 27 890 Ships in 10 - 15 working days

Translational medicine addresses the gap between research and the clinical application of new discoveries. To efficiently deliver new drugs to care centers, a preclinical evaluation, both in vitro and in vivo, is required to ensure that the most active and least toxic compounds are selected as well as to predict clinical outcome. Antimicrobial nanomedicines have been shown to have higher specificity in their therapeutic targets and the ability to serve as adjuvants, increasing the effectiveness of pre-existing immune compounds. The design and development of new standardized protocols for evaluating antimicrobial nanomedicines is needed for both the industry and clinical laboratory. These protocols must aim to evaluate laboratory activity and present models of pharmacokinetic-pharmacodynamic and toxicokinetic behavior that predict absorption and distribution. Likewise, these protocols must follow a theranostics approach, be able to detect promising formulations, diagnose the infectious disease, and determine the correct treatment to implement a personalized therapeutic behavior. Given the possibilities that nanotechnology offers, not updating to new screening platforms is inadequate as it prevents the correct application of discoveries, increasing the effect of the valley of death between innovations and their use. This book is structured to discuss the fundamentals taken into account for the design of robust, reproducible and automatable evaluation platforms. These vital platforms should enable the discovery of new medicines with which to face antimicrobial resistance (RAM), one of the great problems of our time.

Preclinical Evaluation of Antimicrobial Nanodrugs (Paperback, 1st ed. 2020): Juan Bueno Preclinical Evaluation of Antimicrobial Nanodrugs (Paperback, 1st ed. 2020)
Juan Bueno
R2,789 Discovery Miles 27 890 Ships in 10 - 15 working days

Translational medicine addresses the gap between research and the clinical application of new discoveries. To efficiently deliver new drugs to care centers, a preclinical evaluation, both in vitro and in vivo, is required to ensure that the most active and least toxic compounds are selected as well as to predict clinical outcome. Antimicrobial nanomedicines have been shown to have higher specificity in their therapeutic targets and the ability to serve as adjuvants, increasing the effectiveness of pre-existing immune compounds. The design and development of new standardized protocols for evaluating antimicrobial nanomedicines is needed for both the industry and clinical laboratory. These protocols must aim to evaluate laboratory activity and present models of pharmacokinetic-pharmacodynamic and toxicokinetic behavior that predict absorption and distribution. Likewise, these protocols must follow a theranostics approach, be able to detect promising formulations, diagnose the infectious disease, and determine the correct treatment to implement a personalized therapeutic behavior. Given the possibilities that nanotechnology offers, not updating to new screening platforms is inadequate as it prevents the correct application of discoveries, increasing the effect of the valley of death between innovations and their use. This book is structured to discuss the fundamentals taken into account for the design of robust, reproducible and automatable evaluation platforms. These vital platforms should enable the discovery of new medicines with which to face antimicrobial resistance (RAM), one of the great problems of our time.

Molecular Evolutionary Models in Drug Discovery (Paperback): Juan Bueno Molecular Evolutionary Models in Drug Discovery (Paperback)
Juan Bueno
R3,043 Discovery Miles 30 430 Ships in 12 - 17 working days

Molecular Evolutionary Models in Drug Discovery explores the application of evolutionary molecular models in drug discovery in which secondary metabolites play a fundamental role. Secondary metabolites are not produced in isolation, they are the result of the interaction of genes, metabolism and the environment. The book examines the role of secondary metabolites as leads in drug discovery and on the development of a rational bioprospecting model for new medicines based on the evolution of secondary metabolism. These evolutionary models are part of biological systems and are the most reliable expression of the functioning of living beings.

Equipos de trabajo orientados al exito - El pilar que sustenta las organizaciones competitivas (Spanish, Paperback): May... Equipos de trabajo orientados al exito - El pilar que sustenta las organizaciones competitivas (Spanish, Paperback)
May Ferreira, Juan Bueno
bundle available
R218 Discovery Miles 2 180 Ships in 10 - 15 working days
La ruta de la Transformacion Digital - Descubre las claves de la digitalizacion en la empresa (Spanish, Paperback): May... La ruta de la Transformacion Digital - Descubre las claves de la digitalizacion en la empresa (Spanish, Paperback)
May Ferreira, Juan Bueno
bundle available
R746 Discovery Miles 7 460 Ships in 10 - 15 working days
Free Delivery
Pinterest Twitter Facebook Google+
You may like...
Elecstor 18W In-Line UPS (Black)
R999 R404 Discovery Miles 4 040
Loot
Nadine Gordimer Paperback  (2)
R383 R318 Discovery Miles 3 180
Casio LW-200-7AV Watch with 10-Year…
R999 R884 Discovery Miles 8 840
Professor Snape Wizard Wand - In…
 (8)
R801 Discovery Miles 8 010
Loot
Nadine Gordimer Paperback  (2)
R383 R318 Discovery Miles 3 180
Loot
Nadine Gordimer Paperback  (2)
R383 R318 Discovery Miles 3 180
The Girl On the Train
Emily Blunt, Rebecca Ferguson, … Blu-ray disc  (1)
R61 Discovery Miles 610
Bostik Paper Glue - Clear (118ml)
R30 R23 Discovery Miles 230
Dig & Discover: Ancient Egypt - Excavate…
Hinkler Pty Ltd Kit R263 Discovery Miles 2 630
Happier Than Ever
Billie Eilish CD  (1)
R401 Discovery Miles 4 010

 

Partners