This textbook is clearly structured with fourteen richly illustrated chapters and practical examples for easy understanding and direct implementation. The methods and findings developed in the authors' group are presented in detailed, revised chapters. Readers will find valuable updates on the molecular basis of biotechnological processes, secondary metabolite production and genetic engineering. In addition, the basic principles of important biotechnologies, as well as examples of specially designed crops that deliver improved productivity under stress conditions, are presented. This second edition sets the direction for future research on the basic aspects of plant tissue culture and its applications in the fields of secondary metabolite production and genetic engineering. It provides both general and specific information for students, teachers, academic researchers and industrial teams who are interested in new developments in plant tissue culture and its applications.

Nasal continuous positive airway pressure ventilation is the gold standard in the treatment of obstructive sleep apnea. Long-term compliance rates are about 60%. Therefore, several alternative treatment options are of special interest. Beside conservative therapies, various surgical concepts exist. The field of surgery for sleep disordered breathing has rapidly grown with new instrumentation and surgical techniques in the last 10 years. Surgeons in these fields have to attend scientific meetings, participate in workshops, and read the literature to stay up to date. In our sleep laboratories we conduct 30 polysomnographies each night. Each year, we perform almost 1,000 surgical procedures for sleep disordered breathing apart from numerous other conservative and apparative treatment modalities. Referring to our expe- ence and the present literature, we tried to give new information on surgical techniques in this second edition. The chapters are grouped in different anatomical fields of interest. We wanted to give general advice and specific new hints for the surgery of sleep disordered breathing so that the reader learns basic techniques followed by more advanced surgery. In addition to the illustrated surgical descriptions, the chapters contain informations about indications and contraindications of each surgical procedure and the postoperative care. Special interest has been dedicated to evidence-based medicine. So in each chapter, there is a table of references summarizing the effectiveness of the procedure and EBM grade.

This self-contained text is an excellent introduction to Lie groups and their actions on manifolds. The authors start with an elementary discussion of matrix groups, followed by chapters devoted to the basic structure and representation theory of finite dimensinal Lie algebras. They then turn to global issues, demonstrating the key issue of the interplay between differential geometry and Lie theory. Special emphasis is placed on homogeneous spaces and invariant geometric structures. The last section of the book is dedicated to the structure theory of Lie groups. Particularly, they focus on maximal compact subgroups, dense subgroups, complex structures, and linearity. This text is accessible to a broad range of mathematicians and graduate students; it will be useful both as a graduate textbook and as a research reference.

It must have been some feeling of frustration invoked by the genus loci of big conferences which brought Don Dougall, Mike Fowler, and me over a cup of coffee to think of organizing a small meeting on cell culture metabol ism. The basic aim was to bring people working on "primary metabolism" and those who work on "secondary metabolism" to interact with each other, hopefully to induce some new approaches to utilize the cell culture technique more efficiently in basic research and in its practical application. The out come of this was the small symposium at SchloE Rauischholzhausen near GieEen (Germany), and the reader of this small volume of articles on topics discussed will judge to what extent this aim was realized. Although F.e. Steward was unable to attend the meeting, we were happy that he contributed a review on some important turning points of the cell culture method in the past, and at the end of the book some participants of the meeting attempted some prognosis on possible future developments, summarized by Mike Fowler. It was the wish of our publisher to organize the contributions as a summary of the major topics of research of the individual groups represented at the meeting. Due to this, some readers will certainly feel that important areas of research in the cell culture field are missing. This is regrettable, but space had to be limited to keep this volume at a reasonable price."

The adv antages of those systems are counterbalanced by some important dis- vantages. For one, in heterotrophic and mixotrophic systems high concentrations of organic ingredients are required in the nutrient medium (particularly sugar at 2% or more), associated with a high risk of microbial contamination. How, and to which extent this can be avoided will be dealt with in Chapter 3. Other disadvantages are the difficulties and limitations of extrapolating results based on tissue or cell c- tures, to interpreting phenomena occurring in an intact plant during its development. It has always to be kept in mind that tissue cultures are only model systems, with all positive and negative characteristics inherent of such experimental setups. To be realistic, a direct duplication of in situ conditions in tissue culture systems is still not possible even today in the 21st century, and probably never will be. The organization of the genetic system and of basic cell structures is, however, essentially the same, and therefore tissue cultures of higher plants should be better suited as model s- tems than, e.g., cultures of algae, often employed as model systems in physiological or biochemical investigations. The domain cell and tissue culture is rather broad, and necessarily unspecif ic. In terms of practical aspects, basically five areas can be distinguished (see Figs. 1.1, 1.2 ), which here shall be briefly surveyed before being discussed later at length.

Nasal continuous positive airway pressure ventilation is the gold standard in the treatment of obstructive sleep apnea. Long-term compliance rates are about 60%. Therefore, several alternative treatment options are of special interest. Beside conservative therapies, various surgical concepts exist. The field of surgery for sleep disordered breathing has rapidly grown with new instrumentation and surgical techniques in the last 10 years. Surgeons in these fields have to attend scientific meetings, participate in workshops, and read the literature to stay up to date. In our sleep laboratories we conduct 30 polysomnographies each night. Each year, we perform almost 1,000 surgical procedures for sleep disordered breathing apart from numerous other conservative and apparative treatment modalities. Referring to our expe- ence and the present literature, we tried to give new information on surgical techniques in this second edition. The chapters are grouped in different anatomical fields of interest. We wanted to give general advice and specific new hints for the surgery of sleep disordered breathing so that the reader learns basic techniques followed by more advanced surgery. In addition to the illustrated surgical descriptions, the chapters contain informations about indications and contraindications of each surgical procedure and the postoperative care. Special interest has been dedicated to evidence-based medicine. So in each chapter, there is a table of references summarizing the effectiveness of the procedure and EBM grade.

The aim of the Expositions is to present new and important developments in pure and applied mathematics. Well established in the community over more than two decades, the series offers a large library of mathematical works, including several important classics. The volumes supply thorough and detailed expositions of the methods and ideas essential to the topics in question. In addition, they convey their relationships to other parts of mathematics. The series is addressed to advanced readers interested in a thorough study of the subject. Editorial Board Lev Birbrair, Universidade Federal do Ceara, Fortaleza, Brasil Walter D. Neumann, Columbia University, New York, USA Markus J. Pflaum, University of Colorado, Boulder, USA Dierk Schleicher, Jacobs University, Bremen, Germany Katrin Wendland, University of Freiburg, Germany Honorary Editor Victor P. Maslov, Russian Academy of Sciences, Moscow, Russia Titles in planning include Yuri A. Bahturin, Identical Relations in Lie Algebras (2019) Yakov G. Berkovich, Lev G. Kazarin, and Emmanuel M. Zhmud', Characters of Finite Groups, Volume 2 (2019) Jorge Herbert Soares de Lira, Variational Problems for Hypersurfaces in Riemannian Manifolds (2019) Volker Mayer, Mariusz Urbanski, and Anna Zdunik, Random and Conformal Dynamical Systems (2021) Ioannis Diamantis, Bostjan Gabrovsek, Sofia Lambropoulou, and Maciej Mroczkowski, Knot Theory of Lens Spaces (2021)

Subsemigroups of finite-dimensional Lie groups that are generated by one-parameter semigroups are the subject of this book. It covers basic Lie theory for such semigroups and some closely related topics. These include ordered homogeneous manifolds, where the order is defined by a field of cones, invariant cones in Lie algebras and associated Ol'shanskii semigroups. Applications to representation theory, symplectic geometry and Hardy spaces are also given. The book is written as an efficient guide for those interested in subsemigroups of Lie groups and their applications in various fields of mathematics (see the User's guide at the end of the Introduction). Since it is essentially self-contained and leads directly to the core of the theory, the first part of the book can also serve as an introduction to the subject. The reader is merely expected to be familiar with the basic theory of Lie groups and Lie algebras.

This book provides a comprehensive state-of-the art overview on the main trends in the newest endoscopic, robotic, and minimal invasive surgical innovations. It also aims to give insight on some of the innovative ideas around Gastro-intestinal Surgery and Endoscopy to stimulate further activities. It contains established knowledge in the field of endoscopic and surgical techniques, and the integration of these new findings in updated therapeutic decision making are demonstrated. The text reviews the latest literature on the subjects and describes the decision making to establish new therapeutic options in the management of diseases applying new technologies. These new techniques are described in detail, which provide excellent back-up information for clinicians in daily practice. Written by experts in the field, Innovative Endoscopic and Surgical Technology in the GI Tract is a valuable resource of knowledge for clinicians, surgeons, nurses, technicians, students and researchers with an interest in GI- disease.

Refection Positivity is a central theme at the crossroads of Lie group representations, euclidean and abstract harmonic analysis, constructive quantum field theory, and stochastic processes. This book provides the first presentation of the representation theoretic aspects of Refection Positivity and discusses its connections to those different fields on a level suitable for doctoral students and researchers in related fields. It starts with a general introduction to the ideas and methods involving refection positive Hilbert spaces and the Osterwalder--Schrader transform. It then turns to Reflection Positivity in Lie group representations. Already the case of one-dimensional groups is extremely rich. For the real line it connects naturally with Lax--Phillips scattering theory and for the circle group it provides a new perspective on the Kubo--Martin--Schwinger (KMS) condition for states of operator algebras. For Lie groups Reflection Positivity connects unitary representations of a symmetric Lie group with unitary representations of its Cartan dual Lie group. A typical example is the duality between the Euclidean group E(n) and the Poincare group P(n) of special relativity. It discusses in particular the curved context of the duality between spheres and hyperbolic spaces. Further it presents some new integration techniques for representations of Lie algebras by unbounded operators which are needed for the passage to the dual group. Positive definite functions, kernels and distributions and used throughout as a central tool.

This self-containedtext is an excellent introductionto Lie groups and their actions on manifolds. Theauthors start withan elementarydiscussion of matrix groups, followed by chapters devoted to the basic structure and representation theory of finite dimensinal Lie algebras. They then turn to global issues, demonstrating the key issue of the interplay between differential geometry and Lie theory. Special emphasis is placed on homogeneous spaces and invariant geometric structures. The last section of the book is dedicated to the structure theory of Lie groups. Particularly, they focus on maximal compact subgroups, dense subgroups, complex structures, and linearity.

This text is accessible to a broad range of mathematicians and graduate students; it will be useful both as a graduate textbook and as a research reference."

This collection of invited expository articles focuses on recent developments and trends in infinite-dimensional Lie theory, which has become one of the core areas of modern mathematics. The book is divided into three parts: infinite-dimensional Lie (super-)algebras, geometry of infinite-dimensional Lie (transformation) groups, and representation theory of infinite-dimensional Lie groups.

Part (A) is mainly concerned with the structure and representation theory of infinite-dimensional Lie algebras and contains articles on the structure of direct-limit Lie algebras, extended affine Lie algebras and loop algebras, as well as representations of loop algebras and Kac Moody superalgebras.

The articles in Part (B) examine connections between infinite-dimensional Lie theory and geometry. The topics range from infinite-dimensional groups acting on fiber bundles, corresponding characteristic classes and gerbes, to Jordan-theoretic geometries and new results on direct-limit groups.

The analytic representation theory of infinite-dimensional Lie groups is still very much underdeveloped. The articles in Part (C) develop new, promising methods based on heat kernels, multiplicity freeness, Banach Lie Poisson spaces, and infinite-dimensional generalizations of reductive Lie groups.

Contributors: B. Allison, D. Belti, W. Bertram, J. Faulkner, Ph. Gille, H. Glockner, K.-H. Neeb, E. Neher, I. Penkov, A. Pianzola, D. Pickrell, T.S. Ratiu, N.R. Scheithauer, C. Schweigert, V. Serganova, K. Styrkas, K. Waldorf, and J.A. Wolf."

Nach operativen Eingriffen am Gastrointestinaltrakt treten oft postoperative Syndrome in den Mittelpunkt. Der operativ veranderte Gastrointestinaltrakt fordert vom Endoskopiker ein besonderes Verstandnis und besondere Fahigkeiten, auch ohne Kenntnis des detaillierten Operationsberichtes, den operativen Situs zu beurteilen. In diesem Buch wird erstmalig eine Zusammenstellung von Storungen und Syndromen nach operativen Eingriffen am Gastrointestinaltrakt vorgestellt, wobei der endoskopierende Chirurg selbst die Deutung, Interpretation und gegebenenfalls die Behandlung der Befunde vornimmt. Dabei werden die endoskopischen Besonderheiten der Pathologie und Therapie des Gastrointestinaltraktes post operationem komprimiert und illustriert erlautert. Das Buch soll kompendiumartig die Aufmerksamkeit des Lesers auf potentielle postoperative Storungen und Syndrome richten und durch gezielten endoskopischen Einsatz zur Deutung und Behandlung der Befunde weisen.

Das Buch zeigt, worauf es ankommt, damit ein verbindliches Dokument zwischen Auftraggeber, Benutzer, Betreiber einerseits und Systemanalytiker, Entwerfer, Programmierer, Lieferanten andererseits entsteht. Die Darstellung orientiert sich an dem bewahrten Konzept, wie es sich in der Reihe "Know-how fur das Management" als lesefreundlich erwiesen hat: Links eine Grafik, auf der gegenuberliegenden Seite der erklarende Text, das ganze in gut handhabbaren "24 Schritten". Eine wichtige Orientierungshilfe fur alle Verantwortlichen in IT-Projekten.