|
Showing 1 - 6 of
6 matches in All Departments
Diverse in chemical nature, water soluble and lipid soluble
vitamins are essential micronutrients that react with specific
protein entities and are transported to sites for participation in
intracellular events, both at the genomic and non-genomic levels.
Thus, metabolic pathways and intracellular signaling are influenced
by vitamins or their derivatives through vitamin binding to
specific proteins. Vitamin-Binding Proteins: Functional
Consequences examines the function of various vitamins based on
this binding, as well as their role as antioxidants, leading to
effects on intracellular mechanisms. This book explores the
resulting functional consequences at the level of cells, tissues,
and organs as well as the neurological, endocrine, and immune
systems. The text addresses the effects that lead to both normal
physiological function and pharmacological activity with
significant therapeutic potential in a wide spectrum of disease
processes. Leading experts discuss various vitamins including the
function of retinoids in development, immunity, and obesity; the
role of vitamin D in the immune system, infectious processes, and
cardiovascular disease; and the effects of vitamins E, C, and K on
the vascular system. Chapters cover the therapeutic potential of
the vitamin B6 vitamer pyridoxamine and the lipid-soluble
B1analogue benfotiamine. They also describe various functions of
biotin as well as gene transcriptional regulation through biotin
and biotin-binding proteins. The text addresses folate
receptor-mediated therapeutics, vitamin B12 derivatives in tumor
targeting, and implication of ascorbic acid in different disorders.
Expounding newer areas of vitamin function, this book explores the
interface of physiological vitamin function and pharmacological
vitamin action, offering a broad perspective of possible vitamin
binding therapeutics.
Diverse in chemical nature, water soluble and lipid soluble
vitamins are essential micronutrients that react with specific
protein entities and are transported to sites for participation in
intracellular events, both at the genomic and non-genomic levels.
Thus, metabolic pathways and intracellular signaling are influenced
by vitamins or their derivatives through vitamin binding to
specific proteins. Vitamin-Binding Proteins: Functional
Consequences examines the function of various vitamins based on
this binding, as well as their role as antioxidants, leading to
effects on intracellular mechanisms. This book explores the
resulting functional consequences at the level of cells, tissues,
and organs as well as the neurological, endocrine, and immune
systems. The text addresses the effects that lead to both normal
physiological function and pharmacological activity with
significant therapeutic potential in a wide spectrum of disease
processes. Leading experts discuss various vitamins including the
function of retinoids in development, immunity, and obesity; the
role of vitamin D in the immune system, infectious processes, and
cardiovascular disease; and the effects of vitamins E, C, and K on
the vascular system. Chapters cover the therapeutic potential of
the vitamin B6 vitamer pyridoxamine and the lipid-soluble
B1analogue benfotiamine. They also describe various functions of
biotin as well as gene transcriptional regulation through biotin
and biotin-binding proteins. The text addresses folate
receptor-mediated therapeutics, vitamin B12 derivatives in tumor
targeting, and implication of ascorbic acid in different disorders.
Expounding newer areas of vitamin function, this book explores the
interface of physiological vitamin function and pharmacological
vitamin action, offering a broad perspective of possible vitamin
binding therapeutics.
Cell signaling is at the core of most biological processes from the
simplest to the most complex. In addition to unicellular organisms
possessing the essential ability to receive inputs with regard to
nutrient availability and noxious stimuli, the cells in
multicellular organisms require signaling from adjacent, as well as
distant cells to maintain normal internal function, including
growth, differentiation, and homeostasis. Conversely, the etiology
of many disease processes, such as those involving immune system
dysfunction and tumor development, have been traced to aberrant
cell signaling. Nutrients and Cell Signaling, in presenting
contributions from a wide array of experts in the field, fully
delineates the role of nutrients in cell signaling. The text
emphasizes broad concepts and covers all major groups of nutrients.
Contributors discuss the role of carbohydrates, amino acids,
lipids, vitamins, minerals, and trace elements in essential
processes such as cell proliferation, immune function, and DNA
repair. The editors have organized the work to provide select
examples organized under these contemporary research areas: Nuclear
receptors, transcription factors, and signaling cascades Amino
acids, lipids, and glycation Insulin release, signaling, and
insulin resistance Calcium-dependent signaling Feeding and nutrient
homeostasis Nutrients and Cell Signaling answers the need in the
post-genomic era, for an authoritative resource that provides an
in-depth understanding of how these complex and dynamic
biomolecular networks control cell function. Those professionals
and students in molecular biology, nutrition, biochemistry, as well
as any branch involved with cell signaling and function will find
this book to be an invaluable tool in promoting both understanding
and further inquiry.
This book was first published in 1994. Vitamins are essential
micronutrients available to animal organisms through the diet. This
book takes a fresh approach to vitamin-binding proteins, with
emphasis on the nature of the binding of the vitamin ligand to a
protein and its sequela. The role of vitamin-binding proteins as
initiators of the metabolic response is evaluated. Experts in the
field from around the world present an account of their work on the
interaction of vitamins with specific intracellular systems through
the appropriate binding proteins and how this interaction results
in the biological action of vitamins. The book will be of interest
to research workers and postgraduate students in the field of
biochemistry and nutrition.
This book was first published in 1994. Vitamins are essential
micronutrients available to animal organisms through the diet. This
book takes a fresh approach to vitamin-binding proteins, with
emphasis on the nature of the binding of the vitamin ligand to a
protein and its sequela. The role of vitamin-binding proteins as
initiators of the metabolic response is evaluated. Experts in the
field from around the world present an account of their work on the
interaction of vitamins with specific intracellular systems through
the appropriate binding proteins and how this interaction results
in the biological action of vitamins. The book will be of interest
to research workers and postgraduate students in the field of
biochemistry and nutrition.
Cell signaling is at the core of most biological processes from the
simplest to the most complex. In addition to unicellular organisms
possessing the essential ability to receive inputs with regard to
nutrient availability and noxious stimuli, the cells in
multicellular organisms require signaling from adjacent, as well as
distant cells to maintain normal internal function, including
growth, differentiation, and homeostasis. Conversely, the etiology
of many disease processes, such as those involving immune system
dysfunction and tumor development, have been traced to aberrant
cell signaling. Nutrients and Cell Signaling, in presenting
contributions from a wide array of experts in the field, fully
delineates the role of nutrients in cell signaling. The text
emphasizes broad concepts and covers all major groups of nutrients.
Contributors discuss the role of carbohydrates, amino acids,
lipids, vitamins, minerals, and trace elements in essential
processes such as cell proliferation, immune function, and DNA
repair. The editors have organized the work to provide select
examples organized under these contemporary research areas:
-Nuclear receptors, transcription factors, and signaling cascades
-Amino acids, lipids, and glycation -Insulin release, signaling,
and insulin resistance -Calcium-dependent signaling -Feeding and
nutrient homeostasis Nutrients and Cell Signaling answers the need
in the post-genomic era, for an authoritative resource that
provides an in-depth understanding of how these complex and dynamic
biomolecular networks control cell function. Those professionals
and students in molecular biology, nutrition, biochemistry, as well
as any branch involved with cell signaling andfunction will find
this book to be an invaluable tool in promoting both understanding
and further inquiry.
|
You may like...
Loot
Nadine Gordimer
Paperback
(2)
R398
R330
Discovery Miles 3 300
Sound Of Freedom
Jim Caviezel, Mira Sorvino, …
DVD
R325
R218
Discovery Miles 2 180
|