Cell signaling is at the core of most biological processes from the
simplest to the most complex. In addition to unicellular organisms
possessing the essential ability to receive inputs with regard to
nutrient availability and noxious stimuli, the cells in
multicellular organisms require signaling from adjacent, as well as
distant cells to maintain normal internal function, including
growth, differentiation, and homeostasis. Conversely, the etiology
of many disease processes, such as those involving immune system
dysfunction and tumor development, have been traced to aberrant
cell signaling. Nutrients and Cell Signaling, in presenting
contributions from a wide array of experts in the field, fully
delineates the role of nutrients in cell signaling. The text
emphasizes broad concepts and covers all major groups of nutrients.
Contributors discuss the role of carbohydrates, amino acids,
lipids, vitamins, minerals, and trace elements in essential
processes such as cell proliferation, immune function, and DNA
repair. The editors have organized the work to provide select
examples organized under these contemporary research areas:
-Nuclear receptors, transcription factors, and signaling cascades
-Amino acids, lipids, and glycation -Insulin release, signaling,
and insulin resistance -Calcium-dependent signaling -Feeding and
nutrient homeostasis Nutrients and Cell Signaling answers the need
in the post-genomic era, for an authoritative resource that
provides an in-depth understanding of how these complex and dynamic
biomolecular networks control cell function. Those professionals
and students in molecular biology, nutrition, biochemistry, as well
as any branch involved with cell signaling andfunction will find
this book to be an invaluable tool in promoting both understanding
and further inquiry.
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