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Modeling Neuropsychiatric Disorders in Laboratory Animals serves as
a guide for students and basic investigators in the fields of
behavioral sciences, psychology, neuroscience, psychiatry, and
other professionals interested in the use of animal models in
preclinical research related to human neuropsychiatric disorders.
The text focuses on the rationale and theory of using animal
behavior, both pathological and normal, as a tool for understanding
the neural underpinnings of neuropsychiatric disorders. Chapters
contain discussions on both classical and modern views on the
validation of animal models for neuropsychiatric disorders, also
discussing the utility of endophenotypes in modeling
neuropsychiatric disease. Subsequent chapters deal with four
specific classes of disorders, including anxiety disorders,
depressive disorders, obsessive-compulsive and related disorders.
Final sections discuss the future for the development, validation,
and use of animal models in basic and preclinical research.
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