Today, arylation methods are belonging to the most important reaction types in organic synthesis. Lutz Ackermann, a young and ambitious professor has gathered a number of top international authors to present the first comprehensive book on the topic.
Starting from a historical review, the book covers hot topics like Palladium-catalyzed arylation of N-H and alpha-C-H-acidic Bonds, Copper-catalyzed arylation of N-H and O-H Bonds, direct arylation reactions, carbanion aromatic synthesis, arylation reactions of alkenes, alkynes and much more.
This compact source of high quality information is indispensable to synthetic chemists and those working in the pharmaceutical and chemical industry.

Es ist wohl die Eigenart der meisten "Handbiicher", daB ihre Einzelbande nicht in numerischer Reihenfolge erscheinen. Das hat mehrere Griinde: J e mehr sich der in einem Handbuch zu bearbeitende Wissensbereich mit den verschiedensten Fachdisziplinen, z. B. der Medizin, iiberschneidet und je mehr andere Wissenschaften, wie Physik, Technik und Biologie, ihre Beitrage leisten miissen, urn so schwieriger wird eine zeitliche Koordi- nierung. Hinzu kommt u. v. a., daB manche Gebiete bereits seit einiger Zeit einen (mehr oder weniger) endgiiltigen Entwicklungsstand erreicht haben und damit handbuchmaBig zumindest schneller bearbeitet werden konnen, wahrend andere Fragestellungen ein gewisses "Abwarten" zweckmaBig und auch berechtigt erscheinen lassen. Bei einem "Handbuch der Medizinischen Radiologie" spielen diese und auch noch viele andere Gesichtspunkte verstandlicherweise hinsichtlich des Erscheinungstermins der einzelnen Bande eine ganz wesentliche Rolle. Verlag und Herausgeber freuen sich, mit dem nunmehr abgeschlossenen Band 1/1 allen Interessierten die "Basis" dieses Handbuches vorlegen zu konnen. Grundlage der gesamten Radiologie sind die ionisierenden Strahlungen selbst und namentlich die am 8. November 1895 von W. C. RONTGEN (geb. 27.3. 1845 in Lennep, gest. 10. 2. 1923 in Miinchen) entdeckten Bremsstrahlen, die ihm zu Ehren in aller Welt "Rontgenstrahlen" genannt werden, nachdem er sie selbst als X-Strahlen be- zeichnet hatte. Wegen dieser bewuBten Verkniipfung mit dem Namen von RONTGEN ist es bedauer- lich, daB man gelegentlich gerade diesen Namen des Entdeckers durch falsche Schreib- weise, wie "Roentgen" oder "Rentgen", entstellt. An dieser Stelle sei eine kurze geschichtliche Exkursion gestattet.

About this Publication: Human Dignity: Lodestar for Equality in South Africa provides an in-depth analysis of human dignity and its relationship to equality in South African law. The author argues that human dignity is the attributive key that unlocks the constitutional meaning of equality and unfair discrimination. Equality cannot be usefully debated without first asking the vital question 'Equality of what?' The answer, it is contended, must be 'human dignity'. The philosophical and Abrahamic religious roots of these constitutional concepts of dignity and equality are investigated, then further explored and illustrated in the comparative context of South African, German and Canadian constitutional jurisprudence. Clashes and tensions between rights inevitably occur when the equality and non-discrimination rights of a Bill of Rights are applied horizontally, that is between subjects of the state themselves. The human dignity of the contestants plays a vital role in resolving such tensions and conflicts. Human dignity moreover has a determining function when applying constitutionally mandated restitutionary (compensatory) equality and when determining what the legitimate extent and duration of such restitution is. These issues are also considered in a comparative constitutional context. Peer Reviews: 'Retired Justice Laurie Ackermann was one of the giants of the "Mandela Constitutional Court" appointed in 1994. His new book on human dignity matches the weight and the profundity of his judicial writing on the subject. It is an authoritative, lawyerly and commanding exposition of the value that is the key to South Africa's constitutional future-the dignity of all its peoples.' Justice Edwin Cameron, Justice of the Constitutional Court of South Africa 'In this work, the claim that it is the inherent dignity and worth of every human person that must inform the interpretation and enforcement of the constitutional right to equality is backed up, inter alia, by a useful exposition of the Kantian concept of dignity and an illuminating and context-sensitive engagement with comparative constitutional law. The author's argument is systematically developed within a range of contexts, including anti-discrimination law, disputes over the scope and limits of measures designed to remedy past injustices, and conflicts over the appropriate balance between equality and freedom in cases involving the horizontal application of the Bill of Rights. Throughout, the author presents a well-argued and robust defence of a constitutional vision which places the dignity of the individual at the heart of the Constitution's transformative project. This is an important contribution which is certain to stimulate further analysis and debate.' - Prof Henk Botha, University of Stellenbosch Law Faculty 'The most systematic, theoretically rich, and intellectually provocative treatment in the academic literature to date on the subject of human dignity in South Africa's evolving equality jurisprudence.' Prof Sandra Liebenberg, HF Oppenheimer Professor of Human Rights Law, University of Stellenbosch Law Faculty

Directed metalation is recognized as one of the most useful methodologies for the regio- and stereoselective generation of organometallic species, the generation of which necessarily leads to the selective formation of organic products. Cyclometalation using Li, Mn, and Pd, and directed hydrometalation and carbometalation using Al and Zn, have been utilized for regio- and/or stereoselective synthesis for decades. Recently, a new chelation-assisted methodology has been developed not only for controlling regio- and stereoselectivity of reactions, but also for accelerating reactions. In particular, chelation-methodology has been utilized as a new activation method, in which a carbon-metal bond is generated directly from a C-H bond; a reaction rarely achieved using conventional methods. A wide variety of catalytic functionalization reactions of C-H bonds by the utilization of a chelation, have been developed recently and are comprehensively discussed in this book by leading experts. In addition, new approaches to directed hydrometalation and directed carbometalation as a key step are also discussed. A unique stereo- and regioselective hydroformylation has been developed through the utilization of directed hydrometalation. The regioselective Mizoroki-Heck reaction is another example in which directed carbometalation can be used to achieve a high regioselectivity. These examples emphasize how these innovative methodologies are contributing to different fields of chemistry.

Directed metalation is recognized as one of the most useful methodologies for the regio- and stereoselective generation of organometallic species, the generation of which necessarily leads to the selective formation of organic products. Cyclometalation using Li, Mn, and Pd, and directed hydrometalation and carbometalation using Al and Zn, have been utilized for regio- and/or stereoselective synthesis for decades. Recently, a new chelation-assisted methodology has been developed not only for controlling regio- and stereoselectivity of reactions, but also for accelerating reactions. In particular, chelation-methodology has been utilized as a new activation method, in which a carbon-metal bond is generated directly from a C-H bond; a reaction rarely achieved using conventional methods. A wide variety of catalytic functionalization reactions of C-H bonds by the utilization of a chelation, have been developed recently and are comprehensively discussed in this book by leading experts. In addition, new approaches to directed hydrometalation and directed carbometalation as a key step are also discussed. A unique stereo- and regioselective hydroformylation has been developed through the utilization of directed hydrometalation. The regioselective Mizoroki-Heck reaction is another example in which directed carbometalation can be used to achieve a high regioselectivity. These examples emphasize how these innovative methodologies are contributing to different fields of chemistry.

Filling a gap in the literature, this book comprehensively reviews catalytic addition reactions of (hetero)aromatic hydrocarbons across carbon-carbon multiple bonds. In so doing, it summarizes both the scope as well as the limitations of different catalyst systems and building blocks, while highlighting their application to the synthesis of pharmaceuticals. Focusing on the latest developments, the team of authors comprising leaders in the field covers such topics as the hydroarylation of olefins, alkyne hydroarylation in the presence of transition metal catalysts, reaction of alkynes with arylboronic acids, and allene hydroarylation, as well as the synthesis of functionalized arenes and heteroaromatics. A must-have for synthetic chemists in academia and industry dealing with catalysis, organometallic chemistry, the synthesis of natural products, fine chemicals, pharmaceuticals, and organic materials.

The surname Ackerman(n) had its origins in a person's occupation and referred to a cultivator of the ground, a farmer, husbandman, or ploughman. Today, the original use of the term is obsolete but its legacy as a family name lives on in several variations including, not only Ackerman and Ackermann, but also Akerman, Eckerman, and Ockerman. The dictionary focuses on men and women who were born with the Ackerman(n) surname, in any of its many variations. Most of these people lived during the 1700s and 1800s, although some lived as early as the Middle Ages or as recently as the 1900s. Individuals are listed alphabetically by first name and known biographical information is given in the subjects' entries. Data includes, where available, information on birth, marriage, and death dates and places; the names of parents, spouses, and children; occupation; residence; religious and political affiliations; military service; and education. New to this volume is the family group section, which collects three generations (or more) of a particular family into one chapter for the researchers' easier movement through those generations. The vast majority of information contained herein is new to this volume; however, corrections and additions to Volume 1 have been included.

This dictionary focuses on individuals born with the Ackerman(n) surname, in any of its variations including: Accerman, Acerman, Acherman, Ackermen, Ackermin, Ackkermann, Acraman, Acreman, Acremen, Aikerman, Akarman, Akerman, Akkerman, Akkermans, Akreman,