This monograph is the first of a series which is designed to present in depth timely reviews of subjects related to the blood. Insofar as each subject lends itself, the clinical aspects of each topic will be presented as fully as is appropriate, in addition to the basic features. As a consequence, the various monographs should be found useful not solely by hematologists. Depending on the nature of each topic, it is expected that these monographs will be found important by physiologists and specialists in fields other than hematology, as well as by scientists of very diverse interests. The present treatise illus trates this point. Doctors Garby and Meldon have brought together in a most useful way the spectacular advances which have been made in the last decade or two in a field of fundamental biologic impor tance. They have also brought to the discussion of this subject their own observations and interpretations as well as their profound understanding of the respiratory functions of the blood. Maxwell M. Wintrobe Salt Lake City, Utah v Preface This volume is an attempt to summarize the present state of know ledge of the respiratory functions of blood in health and disease. Though it deals fairly thoroughly with physicochemical aspects of the blood's gas transport properties and with the molecular chemis try of hemoglobin, its main emphasis is the gas transport function of the blood in vivo and modes of its disturbance in disease."

Bioenergetics is the name given to the collection of disciplines within biochemistry and physiology that aims at a description and understanding of the function of living systems. These functions include the exchange, metabolism and accumulation of matter, as well as their related energy transformations. The authors present an accessible textbook, providing the reader with the fundamental principles of the subject and how these can then be applied to practical problems. This textbook is ideal for graduate students and researchers in biochemistry, physiology and chemistry. The book should also be of interest to workers in the applied life sciences.

Bioenergetics is the name given to the collection of disciplines within biochemistry and physiology that aims at a description and understanding of the function of living systems. These functions include the exchange, metabolism and accumulation of matter, as well as their related energy transformations. The authors present an accessible textbook, providing the reader with the fundamental principles of the subject and how these can then be applied to practical problems. This textbook is ideal for graduate students and researchers in biochemistry, physiology and chemistry. The book should also be of interest to workers in the applied life sciences.