In the middle of the fourteenth century, the Franciscan friar John of Rupescissa sent a dramatic warning to his followers: the last days were coming; the apocalypse was near. Deemed insane by the Christian church, Rupescissa had spent more than a decade confined to prisons--in one case wrapped in chains and locked under a staircase--yet ill treatment could not silence the friar's apocalyptic message. Religious figures who preached the end times were hardly rare in the late Middle Ages, but Rupescissa's teachings were unique. He claimed that knowledge of the natural world, and alchemy in particular, could act as a defense against the plagues and wars of the last days. His melding of apocalyptic prophecy and quasi-scientific inquiry gave rise to a new genre of alchemical writing and a novel cosmology of heaven and earth. Most important, the friar's research represented a remarkable convergence between science and religion. In order to understand scientific knowledge today, Leah DeVun asks that we revisit Rupescissa's life and the critical events of his age--the Black Death, the Hundred Years' War, the Avignon Papacy--through his eyes. Rupescissa treated alchemy as medicine (his work was the conceptual forerunner of pharmacology) and represented the emerging technologies and views that sought to combat famine, plague, religious persecution, and war. The advances he pioneered, along with the exciting strides made by his contemporaries, shed critical light on later developments in medicine, pharmacology, and chemistry.

The Shape of Sex is a pathbreaking history of nonbinary sex, focusing on ideas and individuals who allegedly combined or crossed sex or gender categories from 200-1400 C.E. Ranging widely across premodern European thought and culture, Leah DeVun reveals how and why efforts to define "the human" so often hinged on ideas about nonbinary sex. The Shape of Sex examines a host of thinkers-theologians, cartographers, natural philosophers, lawyers, poets, surgeons, and alchemists-who used ideas about nonbinary sex as conceptual tools to order their political, cultural, and natural worlds. DeVun reconstructs the cultural landscape navigated by individuals whose sex or gender did not fit the binary alongside debates about animality, sexuality, race, religion, and human nature. The Shape of Sex charts an embrace of nonbinary sex in early Christianity, its brutal erasure at the turn of the thirteenth century, and a new enthusiasm for nonbinary transformations at the dawn of the Renaissance. Along the way, DeVun explores beliefs that Adam and Jesus were nonbinary-sexed; images of "monstrous races" in encyclopedias, maps, and illuminated manuscripts; justifications for violence against purportedly nonbinary outsiders such as Jews and Muslims; and the surgical "correction" of bodies that seemed to flout binary divisions. In a moment when questions about sex, gender, and identity have become incredibly urgent, The Shape of Sex casts new light on a complex and often contradictory past. It shows how premodern thinkers created a system of sex and embodiment that both anticipates and challenges modern beliefs about what it means to be male, female-and human.

In the middle of the fourteenth century, the Franciscan friar John of Rupescissa sent a dramatic warning to his followers: the last days were coming; the apocalypse was near. Deemed insane by the Christian church, Rupescissa had spent more than a decade confined to prisons--in one case wrapped in chains and locked under a staircase--yet ill treatment could not silence the friar's apocalyptic message.

Religious figures who preached the end times were hardly rare in the late Middle Ages, but Rupescissa's teachings were unique. He claimed that knowledge of the natural world, and alchemy in particular, could act as a defense against the plagues and wars of the last days. His melding of apocalyptic prophecy and quasi-scientific inquiry gave rise to a new genre of alchemical writing and a novel cosmology of heaven and earth. Most important, the friar's research represented a remarkable convergence between science and religion.

In order to understand scientific knowledge today, Leah DeVun asks that we revisit Rupescissa's life and the critical events of his age--the Black Death, the Hundred Years' War, the Avignon Papacy--through his eyes. Rupescissa treated alchemy as medicine (his work was the conceptual forerunner of pharmacology) and represented the emerging technologies and views that sought to combat famine, plague, religious persecution, and war. The advances he pioneered, along with the exciting strides made by his contemporaries, shed critical light on later developments in medicine, pharmacology, and chemistry.