The present study carried out pharmaceutical dosage and API. From above study, it is concluded that testing of solid dosage form and Active Pharmaceutical ingredient or analysis of solid dosage form and Active Pharmaceutical ingredient used to well developed function of body and work properly.By the above study both drugs are present in good conditions and formed according to pharmacopoeia. These both of drugs safe can be use to treatment of disease.

Leflunomide is a drug with limited water solubility. It exhibits four polymorphic forms I, II, III, IV. In the present study, form II polymorph was formulated using form I. Form II polymorph readily dissolves in water than does form I. The crystals of form I and II polymorph were characterized by IR, DSC, XRPD. Comparison of solubility of form I and form II was done by UV Spectrophotometer. There was a significant increase in solubility of form II. Aqueous film-coated tablets of form I and form II were prepared using the same processing parameters and compared for the rate of dissolution. Form II tablets showed a significant improvement in terms of dissolution rate, drug release and solubili